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Journal Abstract Search

200 related items for PubMed ID: 16246551

  • 1. N-(4-{[4-(1H-Benzoimidazol-2-yl)-arylamino]-methyl}-phenyl)-benzamide derivatives as small molecule heparanase inhibitors.
    Xu YJ, Miao HQ, Pan W, Navarro EC, Tonra JR, Mitelman S, Camara MM, Deevi DS, Kiselyov AS, Kussie P, Wong WC, Liu H.
    Bioorg Med Chem Lett; 2006 Jan 15; 16(2):404-8. PubMed ID: 16246551
    [Abstract] [Full Text] [Related]

  • 2. 1-[4-(1H-Benzoimidazol-2-yl)-phenyl]-3-[4-(1H-benzoimidazol-2-yl)-phenyl]-urea derivatives as small molecule heparanase inhibitors.
    Pan W, Miao HQ, Xu YJ, Navarro EC, Tonra JR, Corcoran E, Lahiji A, Kussie P, Kiselyov AS, Wong WC, Liu H.
    Bioorg Med Chem Lett; 2006 Jan 15; 16(2):409-12. PubMed ID: 16246560
    [Abstract] [Full Text] [Related]

  • 3. 2,3-Dihydro-1,3-dioxo-1H-isoindole-5-carboxylic acid derivatives: a novel class of small molecule heparanase inhibitors.
    Courtney SM, Hay PA, Buck RT, Colville CS, Porter DW, Scopes DI, Pollard FC, Page MJ, Bennett JM, Hircock ML, McKenzie EA, Stubberfield CR, Turner PR.
    Bioorg Med Chem Lett; 2004 Jun 21; 14(12):3269-73. PubMed ID: 15149688
    [Abstract] [Full Text] [Related]

  • 4. Discovery of N-(2-aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide (MGCD0103), an orally active histone deacetylase inhibitor.
    Zhou N, Moradei O, Raeppel S, Leit S, Frechette S, Gaudette F, Paquin I, Bernstein N, Bouchain G, Vaisburg A, Jin Z, Gillespie J, Wang J, Fournel M, Yan PT, Trachy-Bourget MC, Kalita A, Lu A, Rahil J, MacLeod AR, Li Z, Besterman JM, Delorme D.
    J Med Chem; 2008 Jul 24; 51(14):4072-5. PubMed ID: 18570366
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  • 5. Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors.
    Onda K, Shiraki R, Ogiyama T, Yokoyama K, Momose K, Katayama N, Orita M, Yamaguchi T, Furutani M, Hamada N, Takeuchi M, Okada M, Ohta M, Tsukamoto S.
    Bioorg Med Chem; 2008 Dec 01; 16(23):10001-12. PubMed ID: 18952447
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  • 6. SAR and biological evaluation of analogues of a small molecule histone deacetylase inhibitor N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide (MGCD0103).
    Raeppel S, Zhou N, Gaudette F, Leit S, Paquin I, Larouche G, Moradei O, Fréchette S, Isakovic L, Delorme D, Fournel M, Kalita A, Lu A, Trachy-Bourget MC, Yan PT, Liu J, Rahil J, Wang J, Besterman JM, Murakami K, Li Z, Vaisburg A.
    Bioorg Med Chem Lett; 2009 Feb 01; 19(3):644-9. PubMed ID: 19114304
    [Abstract] [Full Text] [Related]

  • 7. 2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors.
    Cole AG, Bohnstedt AC, Paradkar V, Kingsbury C, Quintero JG, Park H, Lu Y, You M, Neagu I, Diller DJ, Letourneau JJ, Shao Y, James RA, Riviello CM, Ho KK, Lin TH, Wang B, Appell KC, Sills M, Quadros E, Kimble EF, Ohlmeyer MH, Webb ML.
    Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6788-92. PubMed ID: 19836234
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  • 10. Furanyl-1,3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivatives: novel classes of heparanase inhibitor.
    Courtney SM, Hay PA, Buck RT, Colville CS, Phillips DJ, Scopes DI, Pollard FC, Page MJ, Bennett JM, Hircock ML, McKenzie EA, Bhaman M, Felix R, Stubberfield CR, Turner PR.
    Bioorg Med Chem Lett; 2005 May 02; 15(9):2295-9. PubMed ID: 15837312
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  • 11. Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.
    Chen L, Li H, Liu J, Zhang L, Liu H, Jiang H.
    Bioorg Med Chem; 2007 Nov 01; 15(21):6763-74. PubMed ID: 17719791
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  • 13. Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide and its biological evaluation.
    Uto Y, Ogata T, Kiyotsuka Y, Miyazawa Y, Ueno Y, Kurata H, Deguchi T, Yamada M, Watanabe N, Takagi T, Wakimoto S, Okuyama R, Konishi M, Kurikawa N, Kono K, Osumi J.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4159-66. PubMed ID: 19541482
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  • 15. Inhibitors of GlyT1 affect glycine transport via discrete binding sites.
    Mezler M, Hornberger W, Mueller R, Schmidt M, Amberg W, Braje W, Ochse M, Schoemaker H, Behl B.
    Mol Pharmacol; 2008 Dec 01; 74(6):1705-15. PubMed ID: 18815213
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  • 16. 2-((1H-Azol-1-yl)methyl)-N-arylbenzamides: novel dual inhibitors of VEGFR-1/2 kinases.
    Kiselyov AS, Semenova M, Semenov VV, Piatnitski E.
    Bioorg Med Chem Lett; 2006 Mar 15; 16(6):1726-30. PubMed ID: 16364640
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