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150 related items for PubMed ID: 16248041

  • 1. Bis(tBuSATE) phosphotriester prodrugs of 8-azaguanosine and 6-methylpurine riboside; bis(pom) phosphotriester prodrugs of 2'-deoxy-4'-thioadenosine and its corresponding 9alpha anomer.
    Rose JD, Parker WB, Secrist JA.
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(5-7):809-13. PubMed ID: 16248041
    [Abstract] [Full Text] [Related]

  • 2. Ester prodrugs of acyclic nucleoside thiophosphonates compared to phosphonates: synthesis, antiviral activity and decomposition study.
    Roux L, Priet S, Payrot N, Weck C, Fournier M, Zoulim F, Balzarini J, Canard B, Alvarez K.
    Eur J Med Chem; 2013 May; 63():869-81. PubMed ID: 23603046
    [Abstract] [Full Text] [Related]

  • 3. Novel approaches for designing 5'-O-ester prodrugs of 3'-azido-2', 3'-dideoxythymidine (AZT).
    Parang K, Wiebe LI, Knaus EE.
    Curr Med Chem; 2000 Oct; 7(10):995-1039. PubMed ID: 10911016
    [Abstract] [Full Text] [Related]

  • 4. Design and evaluation of 5'-modified nucleoside analogs as prodrugs for an E. coli purine nucleoside phosphorylase mutant.
    Parker WB, Allan PW, Ealick SE, Sorscher EJ, Hassan AE, Silamkoti AV, Fowler AT, Waud WR, Secrist JA.
    Nucleosides Nucleotides Nucleic Acids; 2005 Oct; 24(5-7):387-92. PubMed ID: 16247956
    [Abstract] [Full Text] [Related]

  • 5. Design of new mononucleotide prodrugs: aryl (SATE) phosphotriester derivatives.
    Peyrottes S, Schlienger N, Beltran T, Lefebvre I, Pompon A, Gosselin G, Aubertin AM, Imbach JL, Périgaud C.
    Nucleosides Nucleotides Nucleic Acids; 2001 Oct; 20(4-7):315-21. PubMed ID: 11563043
    [Abstract] [Full Text] [Related]

  • 6. Metabolism and in vitro antiretroviral activities of bis(pivaloyloxymethyl) prodrugs of acyclic nucleoside phosphonates.
    Srinivas RV, Robbins BL, Connelly MC, Gong YF, Bischofberger N, Fridland A.
    Antimicrob Agents Chemother; 1993 Oct; 37(10):2247-50. PubMed ID: 8257154
    [Abstract] [Full Text] [Related]

  • 7. Design and synthesis of novel SATE derivatives of acyclic isocytosine and 9-deazaadenine C-nucleosides.
    Liu LJ, Hong JH.
    Nucleosides Nucleotides Nucleic Acids; 2010 Mar; 29(3):257-66. PubMed ID: 20408056
    [Abstract] [Full Text] [Related]

  • 8. Amidate Prodrugs of Deoxythreosyl Nucleoside Phosphonates as Dual Inhibitors of HIV and HBV Replication.
    Liu C, Dumbre SG, Pannecouque C, Huang C, Ptak RG, Murray MG, De Jonghe S, Herdewijn P.
    J Med Chem; 2016 Oct 27; 59(20):9513-9531. PubMed ID: 27748590
    [Abstract] [Full Text] [Related]

  • 9. Understanding the mode of action of L-nucleosides as antiviral agents: a molecular modeling approach.
    Lee K, Chong Y, Chu CK.
    Nucleosides Nucleotides Nucleic Acids; 2001 Oct 27; 20(4-7):385-8. PubMed ID: 11563052
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and antiviral evaluation of 2-amino-6-carbamoylpurine dioxolane nucleoside derivatives and their phosphoramidates prodrugs.
    Cho JH, Bondana L, Detorio MA, Montero C, Bassit LC, Amblard F, Coats SJ, Schinazi RF.
    Bioorg Med Chem; 2014 Dec 01; 22(23):6665-6671. PubMed ID: 25458500
    [Abstract] [Full Text] [Related]

  • 11. Enhancement of nucleoside cytotoxicity through nucleotide prodrugs.
    Rose JD, Parker WB, Someya H, Shaddix SC, Montgomery JA, Secrist JA.
    J Med Chem; 2002 Sep 26; 45(20):4505-12. PubMed ID: 12238929
    [Abstract] [Full Text] [Related]

  • 12. Intracellular delivery of nucleoside monophosphates through a reductase-mediated activation process.
    Puech F, Gosselin G, Lefebvre I, Pompon A, Aubertin AM, Kirn A, Imbach JL.
    Antiviral Res; 1993 Oct 26; 22(2-3):155-74. PubMed ID: 8279810
    [Abstract] [Full Text] [Related]

  • 13. Synthesis of 5'-methylene-phosphonate furanonucleoside prodrugs: application to D-2'-deoxy-2'-α-fluoro-2'-β-C-methyl nucleosides.
    Pradere U, Amblard F, Coats SJ, Schinazi RF.
    Org Lett; 2012 Sep 07; 14(17):4426-9. PubMed ID: 22917194
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of phosphoramidate prodrugs: ProTide approach.
    Serpi M, Madela K, Pertusati F, Slusarczyk M.
    Curr Protoc Nucleic Acid Chem; 2013 Jun 07; Chapter 15():15.5.1-15.5.15. PubMed ID: 23775807
    [Abstract] [Full Text] [Related]

  • 15. Model synthesis of nucleoside boranophosphoramidate with amino acid for prodrug purpose.
    Li P, Shaw BR.
    Nucleosides Nucleotides Nucleic Acids; 2005 Jun 07; 24(5-7):675-8. PubMed ID: 16248012
    [Abstract] [Full Text] [Related]

  • 16. Synthesis of enantiopure pseudo-L-vinylcyclopropyl nucleosides bearing quaternary carbon as potential anti-herpesvirus agent.
    Moon HR, Park AY, Kim KR, Chun MW, Jeong LS.
    Nucleosides Nucleotides Nucleic Acids; 2007 Jun 07; 26(8-9):975-8. PubMed ID: 18058520
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and biological activity of 2-fluoro adenine and 6-methyl purine nucleoside analogs as prodrugs for suicide gene therapy of cancer.
    Silamkoti AV, Allan PW, Hassan AE, Fowler AT, Sorscher EJ, Parker WB, Secrist JA.
    Nucleosides Nucleotides Nucleic Acids; 2005 Jun 07; 24(5-7):881-5. PubMed ID: 16248054
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and anti-HCV activity of a series of β-d-2'-deoxy-2'-dibromo nucleosides and their corresponding phosphoramidate prodrugs.
    Chen Z, Cox BD, Garnier-Amblard EC, McBrayer TR, Coats SJ, Schinazi RF, Amblard F.
    Bioorg Med Chem Lett; 2017 Dec 01; 27(23):5296-5299. PubMed ID: 29066308
    [Abstract] [Full Text] [Related]

  • 19. Nucleoside diphosphate prodrugs.
    Meier C, Jessen HJ, Balzarini J.
    Nucleic Acids Symp Ser (Oxf); 2008 Dec 01; (52):83-4. PubMed ID: 18776264
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and anti-HCV activity of β-d-2'-deoxy-2'-α-chloro-2'-β-fluoro and β-d-2'-deoxy-2'-α-bromo-2'-β-fluoro nucleosides and their phosphoramidate prodrugs.
    Ovadia R, Khalil A, Li H, De Schutter C, Mengshetti S, Zhou S, Bassit L, Coats SJ, Amblard F, Schinazi RF.
    Bioorg Med Chem; 2019 Feb 15; 27(4):664-676. PubMed ID: 30655167
    [Abstract] [Full Text] [Related]


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