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Journal Abstract Search

338 related items for PubMed ID: 16249345

  • 1. Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.
    Conway JG, McDonald B, Parham J, Keith B, Rusnak DW, Shaw E, Jansen M, Lin P, Payne A, Crosby RM, Johnson JH, Frick L, Lin MH, Depee S, Tadepalli S, Votta B, James I, Fuller K, Chambers TJ, Kull FC, Chamberlain SD, Hutchins JT.
    Proc Natl Acad Sci U S A; 2005 Nov 01; 102(44):16078-83. PubMed ID: 16249345
    [Abstract] [Full Text] [Related]

  • 2. Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats.
    Conway JG, Pink H, Bergquist ML, Han B, Depee S, Tadepalli S, Lin P, Crumrine RC, Binz J, Clark RL, Selph JL, Stimpson SA, Hutchins JT, Chamberlain SD, Brodie TA.
    J Pharmacol Exp Ther; 2008 Jul 01; 326(1):41-50. PubMed ID: 18434589
    [Abstract] [Full Text] [Related]

  • 3. c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis.
    Paniagua RT, Chang A, Mariano MM, Stein EA, Wang Q, Lindstrom TM, Sharpe O, Roscow C, Ho PP, Lee DM, Robinson WH.
    Arthritis Res Ther; 2010 Jul 01; 12(1):R32. PubMed ID: 20181277
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  • 4. CSF-1R inhibition attenuates ischemia-induced renal injury and fibrosis by reducing Ly6C+ M2-like macrophage infiltration.
    Deng X, Yang Q, Wang Y, Zhou C, Guo Y, Hu Z, Liao W, Xu G, Zeng R.
    Int Immunopharmacol; 2020 Nov 01; 88():106854. PubMed ID: 32771945
    [Abstract] [Full Text] [Related]

  • 5. Role for cFMS in maintaining alternative macrophage polarization in SIV infection: implications for HIV neuropathogenesis.
    Gerngross L, Lehmicke G, Belkadi A, Fischer T.
    J Neuroinflammation; 2015 Mar 25; 12():58. PubMed ID: 25886134
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  • 6. Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis.
    Crespo O, Kang SC, Daneman R, Lindstrom TM, Ho PP, Sobel RA, Steinman L, Robinson WH.
    J Clin Immunol; 2011 Dec 25; 31(6):1010-20. PubMed ID: 21847523
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  • 11. Genetic and pharmacological targeting of CSF-1/CSF-1R inhibits tumor-associated macrophages and impairs BRAF-induced thyroid cancer progression.
    Ryder M, Gild M, Hohl TM, Pamer E, Knauf J, Ghossein R, Joyce JA, Fagin JA.
    PLoS One; 2013 Dec 25; 8(1):e54302. PubMed ID: 23372702
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  • 12. Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy.
    Priceman SJ, Sung JL, Shaposhnik Z, Burton JB, Torres-Collado AX, Moughon DL, Johnson M, Lusis AJ, Cohen DA, Iruela-Arispe ML, Wu L.
    Blood; 2010 Feb 18; 115(7):1461-71. PubMed ID: 20008303
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  • 14. JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia.
    Manthey CL, Johnson DL, Illig CR, Tuman RW, Zhou Z, Baker JF, Chaikin MA, Donatelli RR, Franks CF, Zeng L, Crysler C, Chen Y, Yurkow EJ, Boczon L, Meegalla SK, Wilson KJ, Wall MJ, Chen J, Ballentine SK, Ott H, Baumann C, Lawrence D, Tomczuk BE, Molloy CJ.
    Mol Cancer Ther; 2009 Nov 18; 8(11):3151-61. PubMed ID: 19887542
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  • 15. The promotion of breast cancer metastasis caused by inhibition of CSF-1R/CSF-1 signaling is blocked by targeting the G-CSF receptor.
    Swierczak A, Cook AD, Lenzo JC, Restall CM, Doherty JP, Anderson RL, Hamilton JA.
    Cancer Immunol Res; 2014 Aug 18; 2(8):765-76. PubMed ID: 25005824
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  • 16. Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood.
    Eda H, Zhang J, Keith RH, Michener M, Beidler DR, Monahan JB.
    Cytokine; 2010 Dec 18; 52(3):215-20. PubMed ID: 20829061
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  • 17. The related adhesion focal tyrosine kinase (RAFTK) is tyrosine phosphorylated and participates in colony-stimulating factor-1/macrophage colony-stimulating factor signaling in monocyte-macrophages.
    Hatch WC, Ganju RK, Hiregowdara D, Avraham S, Groopman JE.
    Blood; 1998 May 15; 91(10):3967-73. PubMed ID: 9573036
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  • 19. A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model.
    Ohno H, Kubo K, Murooka H, Kobayashi Y, Nishitoba T, Shibuya M, Yoneda T, Isoe T.
    Mol Cancer Ther; 2006 Nov 15; 5(11):2634-43. PubMed ID: 17121910
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