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162 related items for PubMed ID: 16251304

  • 1. Amino acid mutations essential to production of an altered PBP 2X conferring high-level beta-lactam resistance in a clinical isolate of Streptococcus pneumoniae.
    Smith AM, Klugman KP.
    Antimicrob Agents Chemother; 2005 Nov; 49(11):4622-7. PubMed ID: 16251304
    [Abstract] [Full Text] [Related]

  • 2. Alterations in PBP 1A essential-for high-level penicillin resistance in Streptococcus pneumoniae.
    Smith AM, Klugman KP.
    Antimicrob Agents Chemother; 1998 Jun; 42(6):1329-33. PubMed ID: 9624469
    [Abstract] [Full Text] [Related]

  • 3. Non-Penicillin-Binding protein mediated high-level penicillin and cephalosporin resistance in a Hungarian clone of Streptococcus pneumoniae.
    Smith AM, Klugman KP.
    Microb Drug Resist; 2000 Jun; 6(2):105-10. PubMed ID: 10990264
    [Abstract] [Full Text] [Related]

  • 4. Penicillin-binding proteins 2b and 2x of Streptococcus pneumoniae are primary resistance determinants for different classes of beta-lactam antibiotics.
    Grebe T, Hakenbeck R.
    Antimicrob Agents Chemother; 1996 Apr; 40(4):829-34. PubMed ID: 8849235
    [Abstract] [Full Text] [Related]

  • 5. Identical penicillin-binding domains in penicillin-binding proteins of Streptococcus pneumoniae clinical isolates with different levels of beta-lactam resistance.
    Chesnel L, Carapito R, Croizé J, Dideberg O, Vernet T, Zapun A.
    Antimicrob Agents Chemother; 2005 Jul; 49(7):2895-902. PubMed ID: 15980366
    [Abstract] [Full Text] [Related]

  • 6. Activities of ceftobiprole and other beta-lactams against Streptococcus pneumoniae clinical isolates from the United States with defined substitutions in penicillin-binding proteins PBP 1a, PBP 2b, and PBP 2x.
    Davies TA, Shang W, Bush K.
    Antimicrob Agents Chemother; 2006 Jul; 50(7):2530-2. PubMed ID: 16801437
    [Abstract] [Full Text] [Related]

  • 7. Complete sequences of six penicillin-binding protein genes from 40 Streptococcus pneumoniae clinical isolates collected in Japan.
    Sanbongi Y, Ida T, Ishikawa M, Osaki Y, Kataoka H, Suzuki T, Kondo K, Ohsawa F, Yonezawa M.
    Antimicrob Agents Chemother; 2004 Jun; 48(6):2244-50. PubMed ID: 15155228
    [Abstract] [Full Text] [Related]

  • 8. Penicillin-Binding Protein Transpeptidase Signatures for Tracking and Predicting β-Lactam Resistance Levels in Streptococcus pneumoniae.
    Li Y, Metcalf BJ, Chochua S, Li Z, Gertz RE, Walker H, Hawkins PA, Tran T, Whitney CG, McGee L, Beall BW.
    mBio; 2016 Jun 14; 7(3):. PubMed ID: 27302760
    [Abstract] [Full Text] [Related]

  • 9. Highly variable penicillin resistance determinants PBP 2x, PBP 2b, and PBP 1a in isolates of two Streptococcus pneumoniae clonal groups, Poland 23F-16 and Poland 6B-20.
    Izdebski R, Rutschmann J, Fiett J, Sadowy E, Gniadkowski M, Hryniewicz W, Hakenbeck R.
    Antimicrob Agents Chemother; 2008 Mar 14; 52(3):1021-7. PubMed ID: 18160523
    [Abstract] [Full Text] [Related]

  • 10. Analysis of penicillin-binding protein genes of clinical isolates of Streptococcus pneumoniae with reduced susceptibility to amoxicillin.
    du Plessis M, Bingen E, Klugman KP.
    Antimicrob Agents Chemother; 2002 Aug 14; 46(8):2349-57. PubMed ID: 12121904
    [Abstract] [Full Text] [Related]

  • 11. Effects of amino acid alterations in penicillin-binding proteins (PBPs) 1a, 2b, and 2x on PBP affinities of penicillin, ampicillin, amoxicillin, cefditoren, cefuroxime, cefprozil, and cefaclor in 18 clinical isolates of penicillin-susceptible, -intermediate, and -resistant pneumococci.
    Nagai K, Davies TA, Jacobs MR, Appelbaum PC.
    Antimicrob Agents Chemother; 2002 May 14; 46(5):1273-80. PubMed ID: 11959556
    [Abstract] [Full Text] [Related]

  • 12. [Effects of amino acid substitutions of penicillin-binding proteins 2B, 1A, 2X on minimal inhibitory concentration of beta-lactams against Streptococcus pneumoniae].
    Xu M, Zhang JH, Ding YF, Tao YZ, Wang ZC.
    Zhonghua Er Ke Za Zhi; 2010 Jan 14; 48(1):60-4. PubMed ID: 20441706
    [Abstract] [Full Text] [Related]

  • 13. Interspecies recombinational events during the evolution of altered PBP 2x genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae.
    Laible G, Spratt BG, Hakenbeck R.
    Mol Microbiol; 1991 Aug 14; 5(8):1993-2002. PubMed ID: 1766375
    [Abstract] [Full Text] [Related]

  • 14. Genetic analyses of penicillin binding protein determinants in multidrug-resistant Streptococcus pneumoniae serogroup 19 CC320/271 clone with high-level resistance to third-generation cephalosporins.
    Ip M, Ang I, Liyanapathirana V, Ma H, Lai R.
    Antimicrob Agents Chemother; 2015 Jul 14; 59(7):4040-5. PubMed ID: 25918136
    [Abstract] [Full Text] [Related]

  • 15. Five independent combinations of mutations can result in low-affinity penicillin-binding protein 2x of Streptococcus pneumoniae.
    Laible G, Hakenbeck R.
    J Bacteriol; 1991 Nov 14; 173(21):6986-90. PubMed ID: 1938899
    [Abstract] [Full Text] [Related]

  • 16. Genetic diversity of penicillin-binding protein 2B and 2X genes from Streptococcus pneumoniae in South Africa.
    Smith AM, Klugman KP, Coffey TJ, Spratt BG.
    Antimicrob Agents Chemother; 1993 Sep 14; 37(9):1938-44. PubMed ID: 8239609
    [Abstract] [Full Text] [Related]

  • 17. Pneumococcal beta-lactam resistance due to a conformational change in penicillin-binding protein 2x.
    Carapito R, Chesnel L, Vernet T, Zapun A.
    J Biol Chem; 2006 Jan 20; 281(3):1771-7. PubMed ID: 16303769
    [Abstract] [Full Text] [Related]

  • 18. Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility.
    Nagano N, Nagano Y, Kimura K, Tamai K, Yanagisawa H, Arakawa Y.
    Antimicrob Agents Chemother; 2008 Dec 20; 52(12):4258-67. PubMed ID: 18809936
    [Abstract] [Full Text] [Related]

  • 19. Analysis of Amino Acid Sequences of Penicillin-Binding Proteins 1a, 2b, and 2x in Invasive Streptococcus pneumoniae Nonsusceptible to Penicillin Isolated from Children in India.
    Varghese R, Neeravi A, Subramanian N, Baskar P, Anandhan K, Veeraraghavan B.
    Microb Drug Resist; 2021 Mar 20; 27(3):311-319. PubMed ID: 32716253
    [Abstract] [Full Text] [Related]

  • 20. Penicillin-binding protein 1A, 2B, and 2X alterations in Canadian isolates of penicillin-resistant Streptococcus pneumoniae.
    Nichol KA, Zhanel GG, Hoban DJ.
    Antimicrob Agents Chemother; 2002 Oct 20; 46(10):3261-4. PubMed ID: 12234855
    [Abstract] [Full Text] [Related]

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