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Journal Abstract Search

148 related items for PubMed ID: 16257201

  • 1. Privileged structure-based quinazolinone natural product-templated libraries: identification of novel tubulin polymerization inhibitors.
    Liu JF, Wilson CJ, Ye P, Sprague K, Sargent K, Si Y, Beletsky G, Yohannes D, Ng SC.
    Bioorg Med Chem Lett; 2006 Feb; 16(3):686-90. PubMed ID: 16257201
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents.
    Lai MJ, Kuo CC, Yeh TK, Hsieh HP, Chen LT, Pan WY, Hsu KY, Chang JY, Liou JP.
    ChemMedChem; 2009 Apr; 4(4):588-93. PubMed ID: 19266513
    [Abstract] [Full Text] [Related]

  • 3. Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.
    Ouyang X, Piatnitski EL, Pattaropong V, Chen X, He HY, Kiselyov AS, Velankar A, Kawakami J, Labelle M, Smith L, Lohman J, Lee SP, Malikzay A, Fleming J, Gerlak J, Wang Y, Rosler RL, Zhou K, Mitelman S, Camara M, Surguladze D, Doody JF, Tuma MC.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1191-6. PubMed ID: 16377187
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
    Romagnoli R, Baraldi PG, Carrion MD, Lopez Cara C, Preti D, Fruttarolo F, Pavani MG, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Balzarini J, Hadfield JA, Brancale A, Hamel E.
    J Med Chem; 2007 May 03; 50(9):2273-7. PubMed ID: 17419607
    [Abstract] [Full Text] [Related]

  • 5. Indole, a core nucleus for potent inhibitors of tubulin polymerization.
    Brancale A, Silvestri R.
    Med Res Rev; 2007 Mar 03; 27(2):209-38. PubMed ID: 16788980
    [Abstract] [Full Text] [Related]

  • 6. Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data.
    Paull KD, Lin CM, Malspeis L, Hamel E.
    Cancer Res; 1992 Jul 15; 52(14):3892-900. PubMed ID: 1617665
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
    Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Hsieh HP, Hamel E.
    J Med Chem; 2008 Mar 13; 51(5):1464-8. PubMed ID: 18260616
    [Abstract] [Full Text] [Related]

  • 8. Design and synthesis of a quinazolinone natural product-templated library with cytotoxic activity.
    Liu JF, Kaselj M, Isome Y, Ye P, Sargent K, Sprague K, Cherrak D, Wilson CJ, Si Y, Yohannes D, Ng SC.
    J Comb Chem; 2006 Mar 13; 8(1):7-10. PubMed ID: 16398546
    [No Abstract] [Full Text] [Related]

  • 9. Antimitotic activity of lobaric acid and a new benzofuran, sakisacaulon A from Stereocaulon sasakii.
    Morita H, Tsuchiya T, Kishibe K, Noya S, Shiro M, Hirasawa Y.
    Bioorg Med Chem Lett; 2009 Jul 01; 19(13):3679-81. PubMed ID: 19481447
    [Abstract] [Full Text] [Related]

  • 10. Effects of alpha-substitutions on structure and biological activity of anticancer chalcones.
    Lawrence NJ, Patterson RP, Ooi LL, Cook D, Ducki S.
    Bioorg Med Chem Lett; 2006 Nov 15; 16(22):5844-8. PubMed ID: 16949281
    [Abstract] [Full Text] [Related]

  • 11. Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product.
    Wipf P, Graham TH, Vogt A, Sikorski RP, Ducruet AP, Lazo JS.
    Chem Biol Drug Des; 2006 Jan 15; 67(1):66-73. PubMed ID: 16492150
    [Abstract] [Full Text] [Related]

  • 12. Structure-based identification of the binding site for the hemiasterlin analogue HTI-286 on tubulin.
    Ravi M, Zask A, Rush TS.
    Biochemistry; 2005 Dec 06; 44(48):15871-9. PubMed ID: 16313189
    [Abstract] [Full Text] [Related]

  • 13. Synthesis of novel diaryl ethers and their evaluation as antimitotic agents.
    In JK, Lee MS, Yang JE, Kwak JH, Lee H, Boovanahalli SK, Lee K, Kim SJ, Moon SK, Lee S, Choi NS, Ahn SK, Jung JK.
    Bioorg Med Chem Lett; 2007 Mar 15; 17(6):1799-802. PubMed ID: 17276056
    [Abstract] [Full Text] [Related]

  • 14. Novel carbazole and acyl-indole antimitotics.
    Barta TE, Barabasz AF, Foley BE, Geng L, Hall SE, Hanson GJ, Jenks M, Ma W, Rice JW, Veal J.
    Bioorg Med Chem Lett; 2009 Jun 01; 19(11):3078-80. PubMed ID: 19394222
    [Abstract] [Full Text] [Related]

  • 15. Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin.
    Kuznetsov G, TenDyke K, Towle MJ, Cheng H, Liu J, Marsh JP, Schiller SE, Spyvee MR, Yang H, Seletsky BM, Shaffer CJ, Marceau V, Yao Y, Suh EM, Campagna S, Fang FG, Kowalczyk JJ, Littlefield BA.
    Mol Cancer Ther; 2009 Oct 01; 8(10):2852-60. PubMed ID: 19825803
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and biological evaluation of 6H-pyrido[2',1':2,3]imidazo[4,5-c]isoquinolin-5(6H)-ones as antimitotic agents and inhibitors of tubulin polymerization.
    Meng T, Wang W, Zhang Z, Ma L, Zhang Y, Miao Z, Shen J.
    Bioorg Med Chem; 2014 Jan 15; 22(2):848-55. PubMed ID: 24360827
    [Abstract] [Full Text] [Related]

  • 17. Benzopyridooxathiazepine derivatives as novel potent antimitotic agents.
    Gallet S, Flouquet N, Carato P, Pfeiffer B, Renard P, Léonce S, Pierré A, Berthelot P, Lebegue N.
    Bioorg Med Chem; 2009 Feb 01; 17(3):1132-8. PubMed ID: 19162484
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and biological evaluation of cinnamido linked pyrrolo[2,1-c][1,4]benzodiazepines as antimitotic agents.
    Kamal A, Balakishan G, Ramakrishna G, Shaik TB, Sreekanth K, Balakrishna M, Rajender, Dastagiri D, Kalivendi SV.
    Eur J Med Chem; 2010 Sep 01; 45(9):3870-84. PubMed ID: 20554354
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and biological activity of 7-phenyl-6,9-dihydro-3H-pyrrolo[3,2-f]quinolin-9-ones: a new class of antimitotic agents devoid of aromatase activity.
    Gasparotto V, Castagliuolo I, Chiarelotto G, Pezzi V, Montanaro D, Brun P, Palù G, Viola G, Ferlin MG.
    J Med Chem; 2006 Mar 23; 49(6):1910-5. PubMed ID: 16539377
    [Abstract] [Full Text] [Related]

  • 20. Novel Natural Product- and Privileged Scaffold-Based Tubulin Inhibitors Targeting the Colchicine Binding Site.
    Dong M, Liu F, Zhou H, Zhai S, Yan B.
    Molecules; 2016 Oct 15; 21(10):. PubMed ID: 27754459
    [Abstract] [Full Text] [Related]

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