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Journal Abstract Search

399 related items for PubMed ID: 16258022

  • 1. DNA repair enzyme, O6-methylguanine DNA methyltransferase, modulates cytotoxicity of camptothecin-derived topoisomerase I inhibitors.
    Kuo CC, Liu JF, Chang JY.
    J Pharmacol Exp Ther; 2006 Feb; 316(2):946-54. PubMed ID: 16258022
    [Abstract] [Full Text] [Related]

  • 2. Transcriptional repression of O6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N'-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells.
    Ma LC, Kuo CC, Liu JF, Chen LT, Chang JY.
    Mol Pharmacol; 2008 Aug; 74(2):517-26. PubMed ID: 18492797
    [Abstract] [Full Text] [Related]

  • 3. Novel mutation of topoisomerase I in rendering cells resistant to camptothecin.
    Chang JY, Liu JF, Juang SH, Liu TW, Chen LT.
    Cancer Res; 2002 Jul 01; 62(13):3716-21. PubMed ID: 12097280
    [Abstract] [Full Text] [Related]

  • 4. Expression of human O6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents.
    Wu ZN, Chan CL, Eastman A, Bresnick E.
    Cancer Res; 1992 Jan 01; 52(1):32-5. PubMed ID: 1727384
    [Abstract] [Full Text] [Related]

  • 5. Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents.
    Kokkinakis DM, Ahmed MM, Delgado R, Fruitwala MM, Mohiuddin M, Albores-Saavedra J.
    Cancer Res; 1997 Dec 01; 57(23):5360-8. PubMed ID: 9393761
    [Abstract] [Full Text] [Related]

  • 6. Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents.
    Srivenugopal KS, Shou J, Mullapudi SR, Lang FF, Rao JS, Ali-Osman F.
    Clin Cancer Res; 2001 May 01; 7(5):1398-409. PubMed ID: 11350911
    [Abstract] [Full Text] [Related]

  • 7. The novel poly(ADP-Ribose) polymerase inhibitor, AG14361, sensitizes cells to topoisomerase I poisons by increasing the persistence of DNA strand breaks.
    Smith LM, Willmore E, Austin CA, Curtin NJ.
    Clin Cancer Res; 2005 Dec 01; 11(23):8449-57. PubMed ID: 16322308
    [Abstract] [Full Text] [Related]

  • 8. Topoisomerase I alteration in a camptothecin-resistant cell line derived from Chinese hamster DC3F cells in culture.
    Tanizawa A, Pommier Y.
    Cancer Res; 1992 Apr 01; 52(7):1848-54. PubMed ID: 1312902
    [Abstract] [Full Text] [Related]

  • 9. Modulation of 1,3-bis-(2-chloroethyl)-1-nitrosourea resistance in human tumor cells using hammerhead ribozymes designed to degrade O6-methylguanine DNA methyltransferase mRNA.
    Zhang Q, Ohannesian DW, Kreklau EL, Erickson LC.
    J Pharmacol Exp Ther; 2001 Jul 01; 298(1):141-7. PubMed ID: 11408535
    [Abstract] [Full Text] [Related]

  • 10. Extraneuronal monoamine transporter expression and DNA repair vis-à-vis 2-chloroethyl-3-sarcosinamide-1-nitrosourea cytotoxicity in human tumor cell lines.
    Chen ZP, Remack J, Brent TP, Mohr G, Panasci LC.
    Clin Cancer Res; 1999 Dec 01; 5(12):4186-90. PubMed ID: 10632359
    [Abstract] [Full Text] [Related]

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  • 12. Altered topoisomerase I expression in two subclones of human CEM leukemia selected for resistance to camptothecin.
    Kapoor R, Slade DL, Fujimori A, Pommier Y, Harker WG.
    Oncol Res; 1995 Dec 01; 7(2):83-95. PubMed ID: 7579731
    [Abstract] [Full Text] [Related]

  • 13. Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer cell line.
    Urasaki Y, Laco GS, Pourquier P, Takebayashi Y, Kohlhagen G, Gioffre C, Zhang H, Chatterjee D, Pantazis P, Pommier Y.
    Cancer Res; 2001 Mar 01; 61(5):1964-9. PubMed ID: 11280753
    [Abstract] [Full Text] [Related]

  • 14. Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells.
    Holm C, Covey JM, Kerrigan D, Pommier Y.
    Cancer Res; 1989 Nov 15; 49(22):6365-8. PubMed ID: 2553254
    [Abstract] [Full Text] [Related]

  • 15. Cross-resistance to camptothecin analogues in a mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase I alterations.
    Yang CJ, Horton JK, Cowan KH, Schneider E.
    Cancer Res; 1995 Sep 15; 55(18):4004-9. PubMed ID: 7664272
    [Abstract] [Full Text] [Related]

  • 16. Bone marrow-derived cells exhibiting lung epithelial cell characteristics are enriched in vivo using methylguanine DNA methyltransferase-mediated drug resistance.
    Reese JS, Roth JC, Gerson SL.
    Stem Cells; 2008 Mar 15; 26(3):675-81. PubMed ID: 18192231
    [Abstract] [Full Text] [Related]

  • 17. Camptothecin-resistant mutants of Chinese hamster ovary cells containing a resistant form of topoisomerase I.
    Gupta RS, Gupta R, Eng B, Lock RB, Ross WE, Hertzberg RP, Caranfa MJ, Johnson RK.
    Cancer Res; 1988 Nov 15; 48(22):6404-10. PubMed ID: 2846151
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  • 19. Strand- and sequence-specific attenuation of N-methyl-N'-nitro-N-nitrosoguanidine-induced G.C to A.T transitions by expression of human 6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells.
    Yang JL, Hsieh FP, Lee PC, Tseng HJ.
    Cancer Res; 1994 Jul 15; 54(14):3857-63. PubMed ID: 8033107
    [Abstract] [Full Text] [Related]

  • 20. Identification of mutations at DNA topoisomerase I responsible for camptothecin resistance.
    Wang LF, Ting CY, Lo CK, Su JS, Mickley LA, Fojo AT, Whang-Peng J, Hwang J.
    Cancer Res; 1997 Apr 15; 57(8):1516-22. PubMed ID: 9108454
    [Abstract] [Full Text] [Related]

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