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242 related items for PubMed ID: 16258364

  • 1. Nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-XL, (-)-Gossypol, enhances biological effect of genistein against BxPC-3 human pancreatic cancer cell line.
    Mohammad RM, Wang S, Banerjee S, Wu X, Chen J, Sarkar FH.
    Pancreas; 2005 Nov; 31(4):317-24. PubMed ID: 16258364
    [Abstract] [Full Text] [Related]

  • 2. Cisplatin-induced antitumor activity is potentiated by the soy isoflavone genistein in BxPC-3 pancreatic tumor xenografts.
    Mohammad RM, Banerjee S, Li Y, Aboukameel A, Kucuk O, Sarkar FH.
    Cancer; 2006 Mar 15; 106(6):1260-8. PubMed ID: 16475211
    [Abstract] [Full Text] [Related]

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  • 4. Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma.
    Mohammad RM, Wang S, Aboukameel A, Chen B, Wu X, Chen J, Al-Katib A.
    Mol Cancer Ther; 2005 Jan 15; 4(1):13-21. PubMed ID: 15657349
    [Abstract] [Full Text] [Related]

  • 5. Inactivation of nuclear factor kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells.
    Li Y, Ahmed F, Ali S, Philip PA, Kucuk O, Sarkar FH.
    Cancer Res; 2005 Aug 01; 65(15):6934-42. PubMed ID: 16061678
    [Abstract] [Full Text] [Related]

  • 6. Induction of apoptosis and antitumor effects of a small molecule inhibitor of Bcl-2 and Bcl-xl, gossypol acetate, in multiple myeloma in vitro and in vivo.
    Lin J, Wu Y, Yang D, Zhao Y.
    Oncol Rep; 2013 Aug 01; 30(2):731-8. PubMed ID: 23708869
    [Abstract] [Full Text] [Related]

  • 7. Bcl-xL inhibition by molecular-targeting drugs sensitizes human pancreatic cancer cells to TRAIL.
    Hari Y, Harashima N, Tajima Y, Harada M.
    Oncotarget; 2015 Dec 08; 6(39):41902-15. PubMed ID: 26506422
    [Abstract] [Full Text] [Related]

  • 8. In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer.
    Banerjee S, Zhang Y, Wang Z, Che M, Chiao PJ, Abbruzzese JL, Sarkar FH.
    Int J Cancer; 2007 Feb 15; 120(4):906-17. PubMed ID: 17131310
    [Abstract] [Full Text] [Related]

  • 9. Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells.
    Wang Z, Zhang Y, Li Y, Banerjee S, Liao J, Sarkar FH.
    Mol Cancer Ther; 2006 Mar 15; 5(3):483-93. PubMed ID: 16546962
    [Abstract] [Full Text] [Related]

  • 10. Bcl-2/Bcl-xL inhibitor navitoclax increases the antitumor effect of Chk1 inhibitor prexasertib by inducing apoptosis in pancreatic cancer cells via inhibition of Bcl-xL but not Bcl-2.
    Morimoto Y, Takada K, Takeuchi O, Watanabe K, Hirohara M, Hamamoto T, Masuda Y.
    Mol Cell Biochem; 2020 Sep 15; 472(1-2):187-198. PubMed ID: 32567031
    [Abstract] [Full Text] [Related]

  • 11. Potentiation of the effect of erlotinib by genistein in pancreatic cancer: the role of Akt and nuclear factor-kappaB.
    El-Rayes BF, Ali S, Ali IF, Philip PA, Abbruzzese J, Sarkar FH.
    Cancer Res; 2006 Nov 01; 66(21):10553-9. PubMed ID: 17079479
    [Abstract] [Full Text] [Related]

  • 12. In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells.
    Oliver CL, Bauer JA, Wolter KG, Ubell ML, Narayan A, O'Connell KM, Fisher SG, Wang S, Wu X, Ji M, Carey TE, Bradford CR.
    Clin Cancer Res; 2004 Nov 15; 10(22):7757-63. PubMed ID: 15570010
    [Abstract] [Full Text] [Related]

  • 13. Hyperoside induces apoptosis and inhibits growth in pancreatic cancer via Bcl-2 family and NF-κB signaling pathway both in vitro and in vivo.
    Li Y, Wang Y, Li L, Kong R, Pan S, Ji L, Liu H, Chen H, Sun B.
    Tumour Biol; 2016 Jun 15; 37(6):7345-55. PubMed ID: 26676634
    [Abstract] [Full Text] [Related]

  • 14. Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa.
    Meng Y, Tang W, Dai Y, Wu X, Liu M, Ji Q, Ji M, Pienta K, Lawrence T, Xu L.
    Mol Cancer Ther; 2008 Jul 15; 7(7):2192-202. PubMed ID: 18645028
    [Abstract] [Full Text] [Related]

  • 15. Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer.
    Banerjee S, Zhang Y, Ali S, Bhuiyan M, Wang Z, Chiao PJ, Philip PA, Abbruzzese J, Sarkar FH.
    Cancer Res; 2005 Oct 01; 65(19):9064-72. PubMed ID: 16204081
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of nuclear factor kappab activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells.
    Wang Z, Zhang Y, Banerjee S, Li Y, Sarkar FH.
    Int J Cancer; 2006 Apr 15; 118(8):1930-6. PubMed ID: 16284950
    [Abstract] [Full Text] [Related]

  • 17. Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family.
    Ohno I, Eibl G, Odinokova I, Edderkaoui M, Damoiseaux RD, Yazbec M, Abrol R, Goddard WA, Yokosuka O, Pandol SJ, Gukovskaya AS.
    Am J Physiol Gastrointest Liver Physiol; 2010 Jan 15; 298(1):G63-73. PubMed ID: 19762431
    [Abstract] [Full Text] [Related]

  • 18. Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells.
    Srivastava SK, Singh SV.
    Carcinogenesis; 2004 Sep 15; 25(9):1701-9. PubMed ID: 15117814
    [Abstract] [Full Text] [Related]

  • 19. Preclinical studies of apogossypolone, a novel pan inhibitor of bcl-2 and mcl-1, synergistically potentiates cytotoxic effect of gemcitabine in pancreatic cancer cells.
    Banerjee S, Choi M, Aboukameel A, Wang Z, Mohammad M, Chen J, Yang D, Sarkar FH, Mohammad RM.
    Pancreas; 2010 Apr 15; 39(3):323-31. PubMed ID: 19823097
    [Abstract] [Full Text] [Related]

  • 20. Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2.
    Lei X, Chen Y, Du G, Yu W, Wang X, Qu H, Xia B, He H, Mao J, Zong W, Liao X, Mehrpour M, Hao X, Chen Q.
    FASEB J; 2006 Oct 15; 20(12):2147-9. PubMed ID: 16935937
    [Abstract] [Full Text] [Related]

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