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Journal Abstract Search

217 related items for PubMed ID: 16259761

  • 1. Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT(1A) receptor.
    Perrone R, Berardi F, Colabufo NA, Lacivita E, Larizza C, Leopoldo M, Tortorella V.
    J Pharm Pharmacol; 2005 Oct; 57(10):1319-27. PubMed ID: 16259761
    [Abstract] [Full Text] [Related]

  • 2. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Niso M, Perrone R, Tortorella V.
    J Med Chem; 2004 Dec 16; 47(26):6616-24. PubMed ID: 15588097
    [Abstract] [Full Text] [Related]

  • 3. New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
    Jurczyk S, Kołaczkowski M, Maryniak E, Zajdel P, Pawłowski M, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E, Bojarski AJ, Charakchieva-Minol S, Duszyńska B, Nowak G, Maciag D.
    J Med Chem; 2004 May 06; 47(10):2659-66. PubMed ID: 15115407
    [Abstract] [Full Text] [Related]

  • 4. New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation.
    Fiorino F, Perissutti E, Severino B, Santagada V, Cirillo D, Terracciano S, Massarelli P, Bruni G, Collavoli E, Renner C, Caliendo G.
    J Med Chem; 2005 Aug 25; 48(17):5495-503. PubMed ID: 16107148
    [Abstract] [Full Text] [Related]

  • 5. Allosteric modulation of 5-HT(1A) receptors by zinc: Binding studies.
    Barrondo S, Sallés J.
    Neuropharmacology; 2009 Feb 25; 56(2):455-62. PubMed ID: 18951909
    [Abstract] [Full Text] [Related]

  • 6. Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT7 and 5-HT1A receptors.
    Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Perrone R, Tortorella V.
    J Pharm Pharmacol; 2004 Feb 25; 56(2):247-55. PubMed ID: 15005884
    [Abstract] [Full Text] [Related]

  • 7. Differential effects of the 5-hydroxytryptamine (5-HT)1A receptor inverse agonists Rec 27/0224 and Rec 27/0074 on electrophysiological responses to 5-HT1A receptor activation in rat dorsal raphe nucleus and hippocampus in vitro.
    Corradetti R, Mlinar B, Falsini C, Pugliese AM, Cilia A, Destefani C, Testa R.
    J Pharmacol Exp Ther; 2005 Oct 25; 315(1):109-17. PubMed ID: 15951403
    [Abstract] [Full Text] [Related]

  • 8. Novel class of arylpiperazines containing N-acylated amino acids: their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation.
    Zajdel P, Subra G, Bojarski AJ, Duszyńska B, Tatarczyńska E, Nikiforuk A, Chojnacka-Wójcik E, Pawłowski M, Martinez J.
    Bioorg Med Chem; 2007 Apr 15; 15(8):2907-19. PubMed ID: 17321139
    [Abstract] [Full Text] [Related]

  • 9. Stress-induced hyperthermia and basal body temperature are mediated by different 5-HT(1A) receptor populations: a study in SERT knockout rats.
    Olivier JD, Cools AR, Olivier B, Homberg JR, Cuppen E, Ellenbroek BA.
    Eur J Pharmacol; 2008 Aug 20; 590(1-3):190-7. PubMed ID: 18606402
    [Abstract] [Full Text] [Related]

  • 10. Benzimidazole derivatives. Part 5: design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands.
    López-Rodríguez ML, Benhamú B, Morcillo MJ, Tejada I, Avila D, Marco I, Schiapparelli L, Frechilla D, Del Río J.
    Bioorg Med Chem; 2004 Oct 01; 12(19):5181-91. PubMed ID: 15351401
    [Abstract] [Full Text] [Related]

  • 11. Indolebutylamines as selective 5-HT(1A) agonists.
    Heinrich T, Böttcher H, Bartoszyk GD, Greiner HE, Seyfried CA, Van Amsterdam C.
    J Med Chem; 2004 Sep 09; 47(19):4677-83. PubMed ID: 15341483
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors.
    Orús L, Pérez-Silanes S, Oficialdegui AM, Martínez-Esparza J, Del Castillo JC, Mourelle M, Langer T, Guccione S, Donzella G, Krovat EM, Poptodorov K, Lasheras B, Ballaz S, Hervías I, Tordera R, Del Río J, Monge A.
    J Med Chem; 2002 Sep 12; 45(19):4128-39. PubMed ID: 12213056
    [Abstract] [Full Text] [Related]

  • 13. Studies toward the discovery of the next generation of antidepressants. Part 6: Dual 5-HT1A receptor and serotonin transporter affinity within a class of arylpiperazinyl-cyclohexyl indole derivatives.
    Zhou D, Zhou P, Evrard DA, Meagher K, Webb M, Harrison BL, Huryn DM, Golembieski J, Hornby GA, Schechter LE, Smith DL, Andree TH, Mewshaw RE.
    Bioorg Med Chem; 2008 Jul 15; 16(14):6707-23. PubMed ID: 18571421
    [Abstract] [Full Text] [Related]

  • 14. Structure-affinity relationship studies on arylpiperazine derivatives related to quipazine as serotonin transporter ligands. Molecular basis of the selectivity SERT/5HT3 receptor.
    Cappelli A, Giuliani G, Gallelli A, Valenti S, Anzini M, Mennuni L, Makovec F, Cupello A, Vomero S.
    Bioorg Med Chem; 2005 May 16; 13(10):3455-60. PubMed ID: 15848758
    [Abstract] [Full Text] [Related]

  • 15. 1,3-Dioxolane-based ligands as rigid analogues of naftopidil: structure-affinity/activity relationships at alpha1 and 5-HT1A receptors.
    Sorbi C, Franchini S, Tait A, Prandi A, Gallesi R, Angeli P, Marucci G, Pirona L, Poggesi E, Brasili L.
    ChemMedChem; 2009 Mar 16; 4(3):393-9. PubMed ID: 19152363
    [Abstract] [Full Text] [Related]

  • 16. Studies toward the discovery of the next generation of antidepressants. 3. Dual 5-HT1A and serotonin transporter affinity within a class of N-aryloxyethylindolylalkylamines.
    Mewshaw RE, Zhou D, Zhou P, Shi X, Hornby G, Spangler T, Scerni R, Smith D, Schechter LE, Andree TH.
    J Med Chem; 2004 Jul 15; 47(15):3823-42. PubMed ID: 15239661
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, anticonvulsant activity and 5-HT1A, 5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione.
    Obniska J, Kołaczkowski M, Bojarski AJ, Duszyńska B.
    Eur J Med Chem; 2006 Jul 15; 41(7):874-81. PubMed ID: 16600439
    [Abstract] [Full Text] [Related]

  • 18. N-[omega-[4-(2-methoxyphenyl)-1-piperazinyl]alkyl]-2-quinolinamines as high-affinity fluorescent 5-HT1A receptor ligands.
    Lacivita E, Leopoldo M.
    J Med Chem; 2008 Mar 13; 51(5):1492-5. PubMed ID: 18269229
    [Abstract] [Full Text] [Related]

  • 19. Role of peripheral 5-HT1A receptors in detrusor over activity associated with partial bladder outlet obstruction in female rats.
    Mittra S, Malhotra S, Naruganahalli KS, Chugh A.
    Eur J Pharmacol; 2007 Apr 30; 561(1-3):189-93. PubMed ID: 17320854
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and pharmacological evaluation of new arylpiperazines N-[4-[4-(aryl) piperazine-1-yl]-phenyl]-amine derivatives: putative role of 5-HT1A receptors.
    Khatri M, Rai SK, Alam S, Vij A, Tiwari M.
    Bioorg Med Chem; 2009 Mar 01; 17(5):1890-7. PubMed ID: 19223188
    [Abstract] [Full Text] [Related]

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