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Journal Abstract Search

214 related items for PubMed ID: 16262250

  • 1. Molecular interactions of nonpeptide agonists and antagonists with the melanocortin-4 receptor.
    Fleck BA, Chen C, Yang W, Huntley R, Markison S, Nickolls SA, Foster AC, Hoare SR.
    Biochemistry; 2005 Nov 08; 44(44):14494-508. PubMed ID: 16262250
    [Abstract] [Full Text] [Related]

  • 2. Substituted NDP-MSH peptides paired with mutant melanocortin-4 receptors demonstrate the role of transmembrane 6 in receptor activation.
    Fleck BA, Ling N, Chen C.
    Biochemistry; 2007 Sep 18; 46(37):10473-83. PubMed ID: 17713970
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  • 3. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A, Wang XS, Joseph CG, Xiang Z, Bauzo RM, Scott JW, Sorensen NB, Shaw AM, Millard WJ, Richards NG, Haskell-Luevano C.
    J Med Chem; 2004 Apr 22; 47(9):2194-207. PubMed ID: 15084118
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  • 4. Receptor-antagonist interactions in the complexes of agouti and agouti-related protein with human melanocortin 1 and 4 receptors.
    Chai BX, Pogozheva ID, Lai YM, Li JY, Neubig RR, Mosberg HI, Gantz I.
    Biochemistry; 2005 Mar 08; 44(9):3418-31. PubMed ID: 15736952
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  • 5. Ligand affinity for amino-terminal and juxtamembrane domains of the corticotropin releasing factor type I receptor: regulation by G-protein and nonpeptide antagonists.
    Hoare SR, Sullivan SK, Schwarz DA, Ling N, Vale WW, Crowe PD, Grigoriadis DE.
    Biochemistry; 2004 Apr 06; 43(13):3996-4011. PubMed ID: 15049707
    [Abstract] [Full Text] [Related]

  • 6. Molecular determinants of melanocortin 4 receptor ligand binding and MC4/MC3 receptor selectivity.
    Nickolls SA, Cismowski MI, Wang X, Wolff M, Conlon PJ, Maki RA.
    J Pharmacol Exp Ther; 2003 Mar 06; 304(3):1217-27. PubMed ID: 12604699
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  • 9. Overlapping, nonidentical binding sites of different classes of nonpeptide antagonists for the human gonadotropin-releasing hormone receptor.
    Betz SF, Reinhart GJ, Lio FM, Chen C, Struthers RS.
    J Med Chem; 2006 Jan 26; 49(2):637-47. PubMed ID: 16420049
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  • 12. Single amino acid residue determinants of non-peptide antagonist binding to the corticotropin-releasing factor1 (CRF1) receptor.
    Hoare SR, Brown BT, Santos MA, Malany S, Betz SF, Grigoriadis DE.
    Biochem Pharmacol; 2006 Jul 14; 72(2):244-55. PubMed ID: 16750175
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  • 13. Multimeric alpha-MSH has increased efficacy to activate the melanocortin MC4 receptor.
    Tiesjema B, Merkestein M, Garner KM, de Krom M, Adan RA.
    Eur J Pharmacol; 2008 May 06; 585(1):24-30. PubMed ID: 18378226
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  • 14. Interactions of human melanocortin 4 receptor with nonpeptide and peptide agonists.
    Pogozheva ID, Chai BX, Lomize AL, Fong TM, Weinberg DH, Nargund RP, Mulholland MW, Gantz I, Mosberg HI.
    Biochemistry; 2005 Aug 30; 44(34):11329-41. PubMed ID: 16114870
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  • 15. Recognition of privileged structures by G-protein coupled receptors.
    Bondensgaard K, Ankersen M, Thøgersen H, Hansen BS, Wulff BS, Bywater RP.
    J Med Chem; 2004 Feb 12; 47(4):888-99. PubMed ID: 14761190
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  • 19. Novel pharmacological MC4R agonists can efficiently activate mutated MC4R from obese patient with impaired endogenous agonist response.
    Roubert P, Dubern B, Plas P, Lubrano-Berthelier C, Alihi R, Auger F, Deoliveira DB, Dong JZ, Basdevant A, Thurieau C, Clément K.
    J Endocrinol; 2010 Nov 12; 207(2):177-83. PubMed ID: 20696697
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