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106 related items for PubMed ID: 16267027

  • 1. N-benzyladriamycin-14-valerate (AD198) induces apoptosis through protein kinase C-delta-induced phosphorylation of phospholipid scramblase 3.
    He Y, Liu J, Durrant D, Yang HS, Sweatman T, Lothstein L, Lee RM.
    Cancer Res; 2005 Nov 01; 65(21):10016-23. PubMed ID: 16267027
    [Abstract] [Full Text] [Related]

  • 2. Phosphorylation of mitochondrial phospholipid scramblase 3 by protein kinase C-delta induces its activation and facilitates mitochondrial targeting of tBid.
    He Y, Liu J, Grossman D, Durrant D, Sweatman T, Lothstein L, Epand RF, Epand RM, Lee RM.
    J Cell Biochem; 2007 Aug 01; 101(5):1210-21. PubMed ID: 17226776
    [Abstract] [Full Text] [Related]

  • 3. Phospholipid scramblase 3 is the mitochondrial target of protein kinase C delta-induced apoptosis.
    Liu J, Chen J, Dai Q, Lee RM.
    Cancer Res; 2003 Mar 15; 63(6):1153-6. PubMed ID: 12649167
    [Abstract] [Full Text] [Related]

  • 4. Role of phospholipid scramblase 3 in the regulation of tumor necrosis factor-alpha-induced apoptosis.
    Liu J, Epand RF, Durrant D, Grossman D, Chi NW, Epand RM, Lee RM.
    Biochemistry; 2008 Apr 15; 47(15):4518-29. PubMed ID: 18358005
    [Abstract] [Full Text] [Related]

  • 5. Hyperthermia-induced apoptosis in Tca8113 cells is inhibited by heat shock protein 27 through blocking phospholipid scramblase 3 phosphorylation.
    Jiang W, Bian L, Ma LJ, Tang RZ, Xun S, He YW.
    Int J Hyperthermia; 2010 Apr 15; 26(6):523-37. PubMed ID: 20569108
    [Abstract] [Full Text] [Related]

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  • 8. Protein kinase PKC delta and c-Abl are required for mitochondrial apoptosis induction by genotoxic stress in the absence of p53, p73 and Fas receptor.
    Lasfer M, Davenne L, Vadrot N, Alexia C, Sadji-Ouatas Z, Bringuier AF, Feldmann G, Pessayre D, Reyl-Desmars F.
    FEBS Lett; 2006 May 15; 580(11):2547-52. PubMed ID: 16631755
    [Abstract] [Full Text] [Related]

  • 9. Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induced mitochondrial pathway to apoptosis and caspase activation is potentiated by phospholipid scramblase-3.
    Ndebele K, Gona P, Jin TG, Benhaga N, Chalah A, Degli-Esposti M, Khosravi-Far R.
    Apoptosis; 2008 Jul 15; 13(7):845-56. PubMed ID: 18491232
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  • 10. Association of protein kinase C delta and phospholipid scramblase 3 in hippocampal mitochondria correlates with neuronal vulnerability to brain ischemia.
    Kowalczyk JE, Beresewicz M, Gajkowska B, Zabłocka B.
    Neurochem Int; 2009 Jul 15; 55(1-3):157-63. PubMed ID: 19428821
    [Abstract] [Full Text] [Related]

  • 11. N-Benzyladriamycin-14-valerate (AD 198) cytotoxicty circumvents Bcr-Abl anti-apoptotic signaling in human leukemia cells and also potentiates imatinib cytotoxicity.
    Lothstein L, Savranskaya L, Sweatman TW.
    Leuk Res; 2007 Aug 15; 31(8):1085-95. PubMed ID: 17187856
    [Abstract] [Full Text] [Related]

  • 12. Phospholipid scramblase-3 regulates cardiolipin de novo biosynthesis and its resynthesis in growing HeLa cells.
    Van Q, Liu J, Lu B, Feingold KR, Shi Y, Lee RM, Hatch GM.
    Biochem J; 2007 Jan 01; 401(1):103-9. PubMed ID: 16939411
    [Abstract] [Full Text] [Related]

  • 13. Novel extranuclear-targeted anthracyclines override the antiapoptotic functions of Bcl-2 and target protein kinase C pathways to induce apoptosis.
    Barrett CM, Lewis FL, Roaten JB, Sweatman TW, Israel M, Cleveland JL, Lothstein L.
    Mol Cancer Ther; 2002 May 01; 1(7):469-81. PubMed ID: 12479265
    [Abstract] [Full Text] [Related]

  • 14. Rottlerin induces pro-apoptotic endoplasmic reticulum stress through the protein kinase C-delta-independent pathway in human colon cancer cells.
    Lim JH, Park JW, Kim SH, Choi YH, Choi KS, Kwon TK.
    Apoptosis; 2008 Nov 01; 13(11):1378-85. PubMed ID: 18807195
    [Abstract] [Full Text] [Related]

  • 15. FTY720 induces apoptosis in hepatocellular carcinoma cells through activation of protein kinase C delta signaling.
    Hung JH, Lu YS, Wang YC, Ma YH, Wang DS, Kulp SK, Muthusamy N, Byrd JC, Cheng AL, Chen CS.
    Cancer Res; 2008 Feb 15; 68(4):1204-12. PubMed ID: 18281497
    [Abstract] [Full Text] [Related]

  • 16. Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells.
    Lim JH, Park JW, Choi KS, Park YB, Kwon TK.
    Carcinogenesis; 2009 May 15; 30(5):729-36. PubMed ID: 19037087
    [Abstract] [Full Text] [Related]

  • 17. The localization of protein kinase Cdelta in different subcellular sites affects its proapoptotic and antiapoptotic functions and the activation of distinct downstream signaling pathways.
    Gomel R, Xiang C, Finniss S, Lee HK, Lu W, Okhrimenko H, Brodie C.
    Mol Cancer Res; 2007 Jun 15; 5(6):627-39. PubMed ID: 17579121
    [Abstract] [Full Text] [Related]

  • 18. N-benzyladriamycin-14-valerate (AD 198) activates protein kinase C-delta holoenzyme to trigger mitochondrial depolarization and cytochrome c release independently of permeability transition pore opening and Ca2+ influx.
    Lothstein L, Savranskaya L, Barrett CM, Israel M, Sweatman TW.
    Anticancer Drugs; 2006 Jun 15; 17(5):495-502. PubMed ID: 16702805
    [Abstract] [Full Text] [Related]

  • 19. Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-associated p38 mitogen-activated protein kinase.
    Boudreau RT, Conrad DM, Hoskin DW.
    Cell Signal; 2007 Jan 15; 19(1):139-51. PubMed ID: 16844342
    [Abstract] [Full Text] [Related]

  • 20. Acinus-provoked protein kinase C delta isoform activation is essential for apoptotic chromatin condensation.
    Hu Y, Liu Z, Yang SJ, Ye K.
    Cell Death Differ; 2007 Dec 15; 14(12):2035-46. PubMed ID: 17721436
    [Abstract] [Full Text] [Related]

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