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338 related items for PubMed ID: 16272172

  • 1. ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells.
    Xu C, Shen G, Yuan X, Kim JH, Gopalkrishnan A, Keum YS, Nair S, Kong AN.
    Carcinogenesis; 2006 Mar; 27(3):437-45. PubMed ID: 16272172
    [Abstract] [Full Text] [Related]

  • 2. Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells.
    Xu C, Shen G, Chen C, Gélinas C, Kong AN.
    Oncogene; 2005 Jun 30; 24(28):4486-95. PubMed ID: 15856023
    [Abstract] [Full Text] [Related]

  • 3. Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2.
    Xu C, Yuan X, Pan Z, Shen G, Kim JH, Yu S, Khor TO, Li W, Ma J, Kong AN.
    Mol Cancer Ther; 2006 Aug 30; 5(8):1918-26. PubMed ID: 16928811
    [Abstract] [Full Text] [Related]

  • 4. c-jun/AP-1 activation does not affect the antiproliferative activity of phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent.
    Yao S, Zhang Y, Li J.
    Mol Carcinog; 2006 Aug 30; 45(8):605-12. PubMed ID: 16652374
    [Abstract] [Full Text] [Related]

  • 5. Phenethyl isothiocyanate-induced apoptosis in p53-deficient PC-3 human prostate cancer cell line is mediated by extracellular signal-regulated kinases.
    Xiao D, Singh SV.
    Cancer Res; 2002 Jul 01; 62(13):3615-9. PubMed ID: 12097262
    [Abstract] [Full Text] [Related]

  • 6. Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells.
    Cho SD, Li G, Hu H, Jiang C, Kang KS, Lee YS, Kim SH, Lu J.
    Nutr Cancer; 2005 Jul 01; 52(2):213-24. PubMed ID: 16201852
    [Abstract] [Full Text] [Related]

  • 7. Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates.
    Chen YR, Wang W, Kong AN, Tan TH.
    J Biol Chem; 1998 Jan 16; 273(3):1769-75. PubMed ID: 9430725
    [Abstract] [Full Text] [Related]

  • 8. Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1.
    Yu R, Jiao JJ, Duh JL, Tan TH, Kong AN.
    Cancer Res; 1996 Jul 01; 56(13):2954-9. PubMed ID: 8674048
    [Abstract] [Full Text] [Related]

  • 9. The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells.
    Hu R, Kim BR, Chen C, Hebbar V, Kong AN.
    Carcinogenesis; 2003 Aug 01; 24(8):1361-7. PubMed ID: 12819185
    [Abstract] [Full Text] [Related]

  • 10. Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
    Xiao D, Johnson CS, Trump DL, Singh SV.
    Mol Cancer Ther; 2004 May 01; 3(5):567-75. PubMed ID: 15141014
    [Abstract] [Full Text] [Related]

  • 11. Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl isothiocyanate (PEITC).
    Keum YS, Owuor ED, Kim BR, Hu R, Kong AN.
    Pharm Res; 2003 Sep 01; 20(9):1351-6. PubMed ID: 14567627
    [Abstract] [Full Text] [Related]

  • 12. The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and sulforaphane in human non-small lung cancer cells.
    Mi L, Wang X, Govind S, Hood BL, Veenstra TD, Conrads TP, Saha DT, Goldman R, Chung FL.
    Cancer Res; 2007 Jul 01; 67(13):6409-16. PubMed ID: 17616701
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis.
    Yang YM, Conaway CC, Chiao JW, Wang CX, Amin S, Whysner J, Dai W, Reinhardt J, Chung FL.
    Cancer Res; 2002 Jan 01; 62(1):2-7. PubMed ID: 11782348
    [Abstract] [Full Text] [Related]

  • 14. Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium.
    Chuang SM, Wang IC, Yang JL.
    Carcinogenesis; 2000 Jul 01; 21(7):1423-32. PubMed ID: 10874022
    [Abstract] [Full Text] [Related]

  • 15. Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells.
    Yeh CT, Yen GC.
    Carcinogenesis; 2005 Dec 01; 26(12):2138-48. PubMed ID: 16033772
    [Abstract] [Full Text] [Related]

  • 16. Benzyl isothiocyanate promotes miR-99a expression through ERK/AP-1-dependent pathway in bladder cancer cells.
    Tsai TF, Chen PC, Lin YC, Chou KY, Chen HE, Ho CY, Lin JF, Hwang TI.
    Environ Toxicol; 2020 Jan 01; 35(1):47-54. PubMed ID: 31587482
    [Abstract] [Full Text] [Related]

  • 17. 10-formyltetrahydrofolate dehydrogenase-induced c-Jun-NH2-kinase pathways diverge at the c-Jun-NH2-kinase substrate level in cells with different p53 status.
    Ghose S, Oleinik NV, Krupenko NI, Krupenko SA.
    Mol Cancer Res; 2009 Jan 01; 7(1):99-107. PubMed ID: 19147541
    [Abstract] [Full Text] [Related]

  • 18. CXCR4 is a novel target of cancer chemopreventative isothiocyanates in prostate cancer cells.
    Sakao K, Vyas AR, Chinni SR, Amjad AI, Parikh R, Singh SV.
    Cancer Prev Res (Phila); 2015 May 01; 8(5):365-74. PubMed ID: 25712054
    [Abstract] [Full Text] [Related]

  • 19. Role of mitogen-activated protein kinases in phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells.
    Xiao D, Choi S, Lee YJ, Singh SV.
    Mol Carcinog; 2005 Jul 01; 43(3):130-40. PubMed ID: 15880419
    [Abstract] [Full Text] [Related]

  • 20. Phenylethyl isothiocyanate induces apoptotic signaling via suppressing phosphatase activity against c-Jun N-terminal kinase.
    Chen YR, Han J, Kori R, Kong AN, Tan TH.
    J Biol Chem; 2002 Oct 18; 277(42):39334-42. PubMed ID: 12171915
    [Abstract] [Full Text] [Related]

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