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623 related items for PubMed ID: 16280046

  • 1. Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells.
    Baugher PJ, Krishnamoorthy L, Price JE, Dharmawardhane SF.
    Breast Cancer Res; 2005; 7(6):R965-74. PubMed ID: 16280046
    [Abstract] [Full Text] [Related]

  • 2. RAC1 GTP-ase signals Wnt-beta-catenin pathway mediated integrin-directed metastasis-associated tumor cell phenotypes in triple negative breast cancers.
    De P, Carlson JH, Jepperson T, Willis S, Leyland-Jones B, Dey N.
    Oncotarget; 2017 Jan 10; 8(2):3072-3103. PubMed ID: 27902969
    [Abstract] [Full Text] [Related]

  • 3. Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
    Morrison Joly M, Williams MM, Hicks DJ, Jones B, Sanchez V, Young CD, Sarbassov DD, Muller WJ, Brantley-Sieders D, Cook RS.
    Breast Cancer Res; 2017 Jun 30; 19(1):74. PubMed ID: 28666462
    [Abstract] [Full Text] [Related]

  • 4. Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines.
    Gest C, Joimel U, Huang L, Pritchard LL, Petit A, Dulong C, Buquet C, Hu CQ, Mirshahi P, Laurent M, Fauvel-Lafève F, Cazin L, Vannier JP, Lu H, Soria J, Li H, Varin R, Soria C.
    BMC Cancer; 2013 Feb 06; 13():63. PubMed ID: 23388133
    [Abstract] [Full Text] [Related]

  • 5. Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion.
    Chan AY, Coniglio SJ, Chuang YY, Michaelson D, Knaus UG, Philips MR, Symons M.
    Oncogene; 2005 Nov 24; 24(53):7821-9. PubMed ID: 16027728
    [Abstract] [Full Text] [Related]

  • 6. Regulation of breast cancer cell motility by T-cell lymphoma invasion and metastasis-inducing protein.
    Adams HC, Chen R, Liu Z, Whitehead IP.
    Breast Cancer Res; 2010 Nov 24; 12(5):R69. PubMed ID: 20819206
    [Abstract] [Full Text] [Related]

  • 7. Increased diacylglycerol kinase ζ expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion.
    Cai K, Mulatz K, Ard R, Nguyen T, Gee SH.
    BMC Cancer; 2014 Mar 19; 14():208. PubMed ID: 24646293
    [Abstract] [Full Text] [Related]

  • 8. Estrogen and resveratrol regulate Rac and Cdc42 signaling to the actin cytoskeleton of metastatic breast cancer cells.
    Azios NG, Krishnamoorthy L, Harris M, Cubano LA, Cammer M, Dharmawardhane SF.
    Neoplasia; 2007 Feb 19; 9(2):147-58. PubMed ID: 17356711
    [Abstract] [Full Text] [Related]

  • 9. The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells.
    Paradiso A, Cardone RA, Bellizzi A, Bagorda A, Guerra L, Tommasino M, Casavola V, Reshkin SJ.
    Breast Cancer Res; 2004 Feb 19; 6(6):R616-28. PubMed ID: 15535843
    [Abstract] [Full Text] [Related]

  • 10. Rho family GTPases, Rac and Cdc42, control the localization of neonatal dentate granule cells during brain development.
    Ito H, Morishita R, Mizuno M, Tabata H, Nagata KI.
    Hippocampus; 2019 Jul 19; 29(7):569-578. PubMed ID: 30387892
    [Abstract] [Full Text] [Related]

  • 11. Enhanced intrinsic migration of aggressive breast cancer cells by inhibition of Rac1 GTPase.
    Zuo Y, Shields SK, Chakraborty C.
    Biochem Biophys Res Commun; 2006 Dec 15; 351(2):361-7. PubMed ID: 17064663
    [Abstract] [Full Text] [Related]

  • 12. Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells.
    Hajdo-Milasinović A, Ellenbroek SI, van Es S, van der Vaart B, Collard JG.
    J Cell Sci; 2007 Feb 15; 120(Pt 4):555-66. PubMed ID: 17244648
    [Abstract] [Full Text] [Related]

  • 13. PAK is required for the disruption of E-cadherin adhesion by the small GTPase Rac.
    Lozano E, Frasa MA, Smolarczyk K, Knaus UG, Braga VM.
    J Cell Sci; 2008 Apr 01; 121(Pt 7):933-8. PubMed ID: 18319303
    [Abstract] [Full Text] [Related]

  • 14. Rac3-mediated transformation requires multiple effector pathways.
    Keller PJ, Gable CM, Wing MR, Cox AD.
    Cancer Res; 2005 Nov 01; 65(21):9883-90. PubMed ID: 16267012
    [Abstract] [Full Text] [Related]

  • 15. Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer.
    Humphries-Bickley T, Castillo-Pichardo L, Hernandez-O'Farrill E, Borrero-Garcia LD, Forestier-Roman I, Gerena Y, Blanco M, Rivera-Robles MJ, Rodriguez-Medina JR, Cubano LA, Vlaar CP, Dharmawardhane S.
    Mol Cancer Ther; 2017 May 01; 16(5):805-818. PubMed ID: 28450422
    [Abstract] [Full Text] [Related]

  • 16. Redundant functions of Rac GTPases in inner ear morphogenesis.
    Grimsley-Myers CM, Sipe CW, Wu DK, Lu X.
    Dev Biol; 2012 Feb 15; 362(2):172-86. PubMed ID: 22182523
    [Abstract] [Full Text] [Related]

  • 17. The Rac3 GTPase in Neuronal Development, Neurodevelopmental Disorders, and Cancer.
    de Curtis I.
    Cells; 2019 Sep 11; 8(9):. PubMed ID: 31514269
    [Abstract] [Full Text] [Related]

  • 18. Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis.
    Monypenny J, Zicha D, Higashida C, Oceguera-Yanez F, Narumiya S, Watanabe N.
    Mol Cell Biol; 2009 May 11; 29(10):2730-47. PubMed ID: 19273601
    [Abstract] [Full Text] [Related]

  • 19. Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration.
    Wells CM, Walmsley M, Ooi S, Tybulewicz V, Ridley AJ.
    J Cell Sci; 2004 Mar 01; 117(Pt 7):1259-68. PubMed ID: 14996945
    [Abstract] [Full Text] [Related]

  • 20. IBP regulates epithelial-to-mesenchymal transition and the motility of breast cancer cells via Rac1, RhoA and Cdc42 signaling pathways.
    Zhang Z, Yang M, Chen R, Su W, Li P, Chen S, Chen Z, Chen A, Li S, Hu C.
    Oncogene; 2014 Jun 26; 33(26):3374-82. PubMed ID: 23975422
    [Abstract] [Full Text] [Related]

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