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Journal Abstract Search

309 related items for PubMed ID: 1628536

  • 1. The role of leukocyte-generated reactive metabolites in the pathogenesis of idiosyncratic drug reactions.
    Uetrecht JP.
    Drug Metab Rev; 1992; 24(3):299-366. PubMed ID: 1628536
    [Abstract] [Full Text] [Related]

  • 2. Drug metabolism by leukocytes and its role in drug-induced lupus and other idiosyncratic drug reactions.
    Uetrecht J.
    Crit Rev Toxicol; 1990; 20(4):213-35. PubMed ID: 2178625
    [Abstract] [Full Text] [Related]

  • 3. Prediction of a new drug's potential to cause idiosyncratic reactions.
    Uetrecht J.
    Curr Opin Drug Discov Devel; 2001 Jan; 4(1):55-9. PubMed ID: 11727323
    [Abstract] [Full Text] [Related]

  • 4. Metabolism of drugs by activated leukocytes: implications for drug-induced lupus and other drug hypersensitivity reactions.
    Uetrecht J.
    Adv Exp Med Biol; 1991 Jan; 283():121-32. PubMed ID: 2068978
    [Abstract] [Full Text] [Related]

  • 5. Mechanism of hypersensitivity reactions: proposed involvement of reactive metabolites generated by activated leukocytes.
    Uetrecht J.
    Trends Pharmacol Sci; 1989 Nov; 10(11):463-7. PubMed ID: 2692259
    [Abstract] [Full Text] [Related]

  • 6. The danger hypothesis applied to idiosyncratic drug reactions.
    Li J, Uetrecht JP.
    Handb Exp Pharmacol; 2010 Nov; (196):493-509. PubMed ID: 20020274
    [Abstract] [Full Text] [Related]

  • 7. Metabolism of hydralazine by activated leukocytes: implications for hydralazine induced lupus.
    Hofstra AH, Matassa LC, Uetrecht JP.
    J Rheumatol; 1991 Nov; 18(11):1673-80. PubMed ID: 1664857
    [Abstract] [Full Text] [Related]

  • 8. Metabolism of isoniazid by activated leukocytes. Possible role in drug-induced lupus.
    Hofstra AH, Li-Muller SM, Uetrecht JP.
    Drug Metab Dispos; 1992 Nov; 20(2):205-10. PubMed ID: 1352211
    [Abstract] [Full Text] [Related]

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  • 10. Metabolism of ticlopidine by activated neutrophils: implications for ticlopidine-induced agranulocytosis.
    Liu ZC, Uetrecht JP.
    Drug Metab Dispos; 2000 Jul; 28(7):726-30. PubMed ID: 10859143
    [Abstract] [Full Text] [Related]

  • 11. In vitro and animal models of drug-induced blood dyscrasias.
    Ip J, Uetrecht JP.
    Environ Toxicol Pharmacol; 2006 Feb; 21(2):135-40. PubMed ID: 21783650
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  • 14. N-chlorination of sulfamethoxazole and dapsone by the myeloperoxidase system.
    Uetrecht JP, Shear NH, Zahid N.
    Drug Metab Dispos; 1993 Feb; 21(5):830-4. PubMed ID: 7902244
    [Abstract] [Full Text] [Related]

  • 15. Blood dyscrasias secondary to non-steroidal anti-inflammatory drugs.
    Miescher PA.
    Med Toxicol; 1986 Feb; 1 Suppl 1():57-70. PubMed ID: 3547002
    [Abstract] [Full Text] [Related]

  • 16. Oxidation of a metabolite of indomethacin (Desmethyldeschlorobenzoylindomethacin) to reactive intermediates by activated neutrophils, hypochlorous acid, and the myeloperoxidase system.
    Ju C, Uetrecht JP.
    Drug Metab Dispos; 1998 Jul; 26(7):676-80. PubMed ID: 9660850
    [Abstract] [Full Text] [Related]

  • 17. Idiosyncratic drug reactions: possible role of reactive metabolites generated by leukocytes.
    Uetrecht JP.
    Pharm Res; 1989 Apr; 6(4):265-73. PubMed ID: 2664753
    [Abstract] [Full Text] [Related]

  • 18. Structural alert/reactive metabolite concept as applied in medicinal chemistry to mitigate the risk of idiosyncratic drug toxicity: a perspective based on the critical examination of trends in the top 200 drugs marketed in the United States.
    Stepan AF, Walker DP, Bauman J, Price DA, Baillie TA, Kalgutkar AS, Aleo MD.
    Chem Res Toxicol; 2011 Sep 19; 24(9):1345-410. PubMed ID: 21702456
    [Abstract] [Full Text] [Related]

  • 19. Peroxidase-mediated bioactivation of hydroxylated metabolites of carbamazepine and phenytoin.
    Lu W, Uetrecht JP.
    Drug Metab Dispos; 2008 Aug 19; 36(8):1624-36. PubMed ID: 18463199
    [Abstract] [Full Text] [Related]

  • 20. Drug bioactivation and protein adduct formation in the pathogenesis of drug-induced toxicity.
    Park BK, Laverty H, Srivastava A, Antoine DJ, Naisbitt D, Williams DP.
    Chem Biol Interact; 2011 Jun 30; 192(1-2):30-6. PubMed ID: 20846520
    [Abstract] [Full Text] [Related]

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