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Journal Abstract Search

144 related items for PubMed ID: 16288019

  • 1. Disruption of protein kinase a regulation causes immortalization and dysregulation of D-type cyclins.
    Nadella KS, Kirschner LS.
    Cancer Res; 2005 Nov 15; 65(22):10307-15. PubMed ID: 16288019
    [Abstract] [Full Text] [Related]

  • 2. Use of mouse models to understand the molecular basis of tissue-specific tumorigenesis in the Carney complex.
    Kirschner LS.
    J Intern Med; 2009 Jul 15; 266(1):60-8. PubMed ID: 19522826
    [Abstract] [Full Text] [Related]

  • 3. Inactivation of the Carney complex gene 1 (protein kinase A regulatory subunit 1A) inhibits SMAD3 expression and TGF beta-stimulated apoptosis in adrenocortical cells.
    Ragazzon B, Cazabat L, Rizk-Rabin M, Assie G, Groussin L, Fierrard H, Perlemoine K, Martinez A, Bertherat J.
    Cancer Res; 2009 Sep 15; 69(18):7278-84. PubMed ID: 19738044
    [Abstract] [Full Text] [Related]

  • 4. Depletion of type IA regulatory subunit (RIalpha) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency.
    Mavrakis M, Lippincott-Schwartz J, Stratakis CA, Bossis I.
    Hum Mol Genet; 2006 Oct 01; 15(19):2962-71. PubMed ID: 16963469
    [Abstract] [Full Text] [Related]

  • 5. A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions.
    Griffin KJ, Kirschner LS, Matyakhina L, Stergiopoulos SG, Robinson-White A, Lenherr SM, Weinberg FD, Claflin ES, Batista D, Bourdeau I, Voutetakis A, Sandrini F, Meoli EM, Bauer AJ, Cho-Chung YS, Bornstein SR, Carney JA, Stratakis CA.
    J Med Genet; 2004 Dec 01; 41(12):923-31. PubMed ID: 15591278
    [Abstract] [Full Text] [Related]

  • 6. Compensatory stabilization of RIIbeta protein, cell cycle deregulation, and growth arrest in colon and prostate carcinoma cells by antisense-directed down-regulation of protein kinase A RIalpha protein.
    Nesterova M, Noguchi K, Park YG, Lee YN, Cho-Chung YS.
    Clin Cancer Res; 2000 Sep 01; 6(9):3434-41. PubMed ID: 10999726
    [Abstract] [Full Text] [Related]

  • 7. Regulatory subunit type I-alpha of protein kinase A (PRKAR1A): a tumor-suppressor gene for sporadic thyroid cancer.
    Sandrini F, Matyakhina L, Sarlis NJ, Kirschner LS, Farmakidis C, Gimm O, Stratakis CA.
    Genes Chromosomes Cancer; 2002 Oct 01; 35(2):182-92. PubMed ID: 12203783
    [Abstract] [Full Text] [Related]

  • 8. Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors.
    Griffin KJ, Kirschner LS, Matyakhina L, Stergiopoulos S, Robinson-White A, Lenherr S, Weinberg FD, Claflin E, Meoli E, Cho-Chung YS, Stratakis CA.
    Cancer Res; 2004 Dec 15; 64(24):8811-5. PubMed ID: 15604237
    [Abstract] [Full Text] [Related]

  • 9. Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.
    Yin Z, Jones GN, Towns WH, Zhang X, Abel ED, Binkley PF, Jarjoura D, Kirschner LS.
    Circulation; 2008 Mar 18; 117(11):1414-22. PubMed ID: 18316483
    [Abstract] [Full Text] [Related]

  • 10. A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues.
    Kirschner LS, Kusewitt DF, Matyakhina L, Towns WH, Carney JA, Westphal H, Stratakis CA.
    Cancer Res; 2005 Jun 01; 65(11):4506-14. PubMed ID: 15930266
    [Abstract] [Full Text] [Related]

  • 11. Proliferation of transformed somatotroph cells related to low or absent expression of protein kinase a regulatory subunit 1A protein.
    Lania AG, Mantovani G, Ferrero S, Pellegrini C, Bondioni S, Peverelli E, Braidotti P, Locatelli M, Zavanone ML, Ferrante E, Bosari S, Beck-Peccoz P, Spada A.
    Cancer Res; 2004 Dec 15; 64(24):9193-8. PubMed ID: 15604292
    [Abstract] [Full Text] [Related]

  • 12. Molecular and functional analysis of PRKAR1A and its locus (17q22-24) in sporadic adrenocortical tumors: 17q losses, somatic mutations, and protein kinase A expression and activity.
    Bertherat J, Groussin L, Sandrini F, Matyakhina L, Bei T, Stergiopoulos S, Papageorgiou T, Bourdeau I, Kirschner LS, Vincent-Dejean C, Perlemoine K, Gicquel C, Bertagna X, Stratakis CA.
    Cancer Res; 2003 Sep 01; 63(17):5308-19. PubMed ID: 14500362
    [Abstract] [Full Text] [Related]

  • 13. Molecular cloning, chromosomal localization of human peripheral-type benzodiazepine receptor and PKA regulatory subunit type 1A (PRKAR1A)-associated protein PAP7, and studies in PRKAR1A mutant cells and tissues.
    Liu J, Matyakhina L, Han Z, Sandrini F, Bei T, Stratakis CA, Papadopoulos V.
    FASEB J; 2003 Jun 01; 17(9):1189-91. PubMed ID: 12692076
    [Abstract] [Full Text] [Related]

  • 14. Evidence that PKA activity is constitutively activated in human GH-secreting adenoma cells in a patient with Carney complex harbouring a PRKAR1A mutation.
    Takano K, Yasufuku-Takano J, Morita K, Mori S, Takei M, Osamura RY, Teramoto A, Fujita T.
    Clin Endocrinol (Oxf); 2009 May 01; 70(5):769-75. PubMed ID: 19178533
    [Abstract] [Full Text] [Related]

  • 15. Chemoprevention with protein kinase A RIalpha antisense in DMBA-mammary carcinogenesis.
    Nesterova MV, Cho-Chung YS.
    Ann N Y Acad Sci; 2005 Nov 01; 1058():255-64. PubMed ID: 16394142
    [Abstract] [Full Text] [Related]

  • 16. Molecular and immunohistochemical investigation of protein kinase a regulatory subunit type 1A (PRKAR1A) in odontogenic myxomas.
    Perdigão PF, Stergiopoulos SG, De Marco L, Matyakhina L, Boikos SA, Gomez RS, Pimenta FJ, Stratakis CA.
    Genes Chromosomes Cancer; 2005 Oct 01; 44(2):204-11. PubMed ID: 16001434
    [Abstract] [Full Text] [Related]

  • 17. Evidence that leptin through STAT and CREB signaling enhances cyclin D1 expression and promotes human endometrial cancer proliferation.
    Catalano S, Giordano C, Rizza P, Gu G, Barone I, Bonofiglio D, Giordano F, Malivindi R, Gaccione D, Lanzino M, De Amicis F, Andò S.
    J Cell Physiol; 2009 Mar 01; 218(3):490-500. PubMed ID: 18988190
    [Abstract] [Full Text] [Related]

  • 18. Inherited disposition to cardiac myxoma development.
    Wilkes D, Charitakis K, Basson CT.
    Nat Rev Cancer; 2006 Feb 01; 6(2):157-65. PubMed ID: 16491075
    [Abstract] [Full Text] [Related]

  • 19. PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex.
    Robinson-White A, Meoli E, Stergiopoulos S, Horvath A, Boikos S, Bossis I, Stratakis CA.
    J Clin Endocrinol Metab; 2006 Jun 01; 91(6):2380-8. PubMed ID: 16569736
    [Abstract] [Full Text] [Related]

  • 20. Mechanisms of deficient type I protein kinase A activity in lupus T lymphocytes.
    Kammer GM, Laxminarayana D, Khan IU.
    Int Rev Immunol; 2004 Jun 01; 23(3-4):225-44. PubMed ID: 15204086
    [Abstract] [Full Text] [Related]

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