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Journal Abstract Search


573 related items for PubMed ID: 16288909

  • 1. Clemastine, a conventional antihistamine, is a high potency inhibitor of the HERG K+ channel.
    Ridley JM, Milnes JT, Hancox JC, Witchel HJ.
    J Mol Cell Cardiol; 2006 Jan; 40(1):107-18. PubMed ID: 16288909
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  • 2. Inhibition of HERG K+ current and prolongation of the guinea-pig ventricular action potential by 4-aminopyridine.
    Ridley JM, Milnes JT, Zhang YH, Witchel HJ, Hancox JC.
    J Physiol; 2003 Jun 15; 549(Pt 3):667-72. PubMed ID: 12740430
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  • 3. H(1) antihistamine drug promethazine directly blocks hERG K(+) channel.
    Jo SH, Hong HK, Chong SH, Lee HS, Choe H.
    Pharmacol Res; 2009 Nov 15; 60(5):429-37. PubMed ID: 19497368
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  • 4. Molecular interaction of droperidol with human ether-a-go-go-related gene channels: prolongation of action potential duration without inducing early afterdepolarization.
    Schwoerer AP, Blütner C, Brandt S, Binder S, Siebrands CC, Ehmke H, Friederich P.
    Anesthesiology; 2007 May 15; 106(5):967-76. PubMed ID: 17457128
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  • 5. Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel.
    Park MH, Lee SH, Chu DH, Won KH, Choi BH, Choe H, Jo SH.
    J Pharmacol Sci; 2013 Sep 20; 123(1):67-77. PubMed ID: 24005046
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  • 8. Ranolazine inhibition of hERG potassium channels: drug-pore interactions and reduced potency against inactivation mutants.
    Du C, Zhang Y, El Harchi A, Dempsey CE, Hancox JC.
    J Mol Cell Cardiol; 2014 Sep 20; 74(100):220-30. PubMed ID: 24877995
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  • 9. Inhibition of the HERG K+ channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656.
    Ridley JM, Milnes JT, Duncan RS, McPate MJ, James AF, Witchel HJ, Hancox JC.
    FEBS Lett; 2006 Apr 03; 580(8):1999-2005. PubMed ID: 16542653
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  • 10. Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin.
    Duncan RS, McPate MJ, Ridley JM, Gao Z, James AF, Leishman DJ, Leaney JL, Witchel HJ, Hancox JC.
    Biochem Pharmacol; 2007 Aug 01; 74(3):425-37. PubMed ID: 17560554
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  • 12. Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline.
    Teschemacher AG, Seward EP, Hancox JC, Witchel HJ.
    Br J Pharmacol; 1999 Sep 01; 128(2):479-85. PubMed ID: 10510461
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  • 14. Altered gating of HERG potassium channels by cobalt and lanthanum.
    Sanchez-Chapula JA, Sanguinetti MC.
    Pflugers Arch; 2000 Jun 01; 440(2):264-74. PubMed ID: 10898527
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  • 15. Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action.
    Thomas D, Hammerling BC, Wu K, Wimmer AB, Ficker EK, Kirsch GE, Kochan MC, Wible BA, Scholz EP, Zitron E, Kathöfer S, Kreye VA, Katus HA, Schoels W, Karle CA, Kiehn J.
    Br J Pharmacol; 2004 Jun 01; 142(3):485-94. PubMed ID: 15148258
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  • 17. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
    Davie C, Pierre-Valentin J, Pollard C, Standen N, Mitcheson J, Alexander P, Thong B.
    J Cardiovasc Electrophysiol; 2004 Nov 01; 15(11):1302-9. PubMed ID: 15574182
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