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Journal Abstract Search

354 related items for PubMed ID: 16288954

  • 1. The Na+ binding channel of human coagulation proteases: novel insights on the structure and allosteric modulation revealed by molecular surface analysis.
    Silva FP, Antunes OA, de Alencastro RB, De Simone SG.
    Biophys Chem; 2006 Feb 01; 119(3):282-94. PubMed ID: 16288954
    [Abstract] [Full Text] [Related]

  • 2. S1 subsite in snake venom thrombin-like enzymes: can S1 subsite lipophilicity be used to sort binding affinities of trypsin-like enzymes to small-molecule inhibitors?
    Silva FP, De-Simone SG.
    Bioorg Med Chem; 2004 May 15; 12(10):2571-87. PubMed ID: 15110839
    [Abstract] [Full Text] [Related]

  • 3. Na+ site in blood coagulation factor IXa: effect on catalysis and factor VIIIa binding.
    Schmidt AE, Stewart JE, Mathur A, Krishnaswamy S, Bajaj SP.
    J Mol Biol; 2005 Jul 01; 350(1):78-91. PubMed ID: 15913649
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  • 4. Regulation of the catalytic function of coagulation factor VIIa by a conformational linkage of surface residue Glu 154 to the active site.
    Shobe J, Dickinson CD, Ruf W.
    Biochemistry; 1999 Mar 02; 38(9):2745-51. PubMed ID: 10052945
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  • 5. Contribution of explicit solvent effects to the binding affinity of small-molecule inhibitors in blood coagulation factor serine proteases.
    Abel R, Salam NK, Shelley J, Farid R, Friesner RA, Sherman W.
    ChemMedChem; 2011 Jun 06; 6(6):1049-66. PubMed ID: 21506273
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  • 6. Energetics of thrombin-thrombomodulin interaction.
    Vindigni A, White CE, Komives EA, Di Cera E.
    Biochemistry; 1997 Jun 03; 36(22):6674-81. PubMed ID: 9184147
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  • 8. In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.
    Costanzo MJ, Almond HR, Hecker LR, Schott MR, Yabut SC, Zhang HC, Andrade-Gordon P, Corcoran TW, Giardino EC, Kauffman JA, Lewis JM, de Garavilla L, Haertlein BJ, Maryanoff BE.
    J Med Chem; 2005 Mar 24; 48(6):1984-2008. PubMed ID: 15771442
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  • 9. Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants.
    Hopfner KP, Brandstetter H, Karcher A, Kopetzki E, Huber R, Engh RA, Bode W.
    EMBO J; 1997 Nov 17; 16(22):6626-35. PubMed ID: 9362477
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  • 10. Molecular Interactions of Thrombin.
    Tulinsky A.
    Semin Thromb Hemost; 1996 Nov 17; 22(2):117-24. PubMed ID: 8807707
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  • 13. The influence of sodium ion binding on factor IXa activity.
    Gopalakrishna K, Rezaie AR.
    Thromb Haemost; 2006 Jun 17; 95(6):936-41. PubMed ID: 16732371
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  • 14. Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex.
    Fuentes-Prior P, Iwanaga Y, Huber R, Pagila R, Rumennik G, Seto M, Morser J, Light DR, Bode W.
    Nature; 2000 Mar 30; 404(6777):518-25. PubMed ID: 10761923
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  • 16. Rational engineering of activity and specificity in a serine protease.
    Dang QD, Guinto ER, di Cera E.
    Nat Biotechnol; 1997 Feb 30; 15(2):146-9. PubMed ID: 9035139
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  • 18. High resolution crystal structures of free thrombin in the presence of K(+) reveal the molecular basis of monovalent cation selectivity and an inactive slow form.
    Carrell CJ, Bush LA, Mathews FS, Di Cera E.
    Biophys Chem; 2006 Jun 01; 121(3):177-84. PubMed ID: 16487650
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