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Journal Abstract Search

110 related items for PubMed ID: 16290140

  • 1. Identification of Darmstoff analogs as selective agonists and antagonists of lysophosphatidic acid receptors.
    Gududuru V, Zeng K, Tsukahara R, Makarova N, Fujiwara Y, Pigg KR, Baker DL, Tigyi G, Miller DD.
    Bioorg Med Chem Lett; 2006 Jan 15; 16(2):451-6. PubMed ID: 16290140
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands.
    Durgam GG, Tsukahara R, Makarova N, Walker MD, Fujiwara Y, Pigg KR, Baker DL, Sardar VM, Parrill AL, Tigyi G, Miller DD.
    Bioorg Med Chem Lett; 2006 Feb 15; 16(3):633-40. PubMed ID: 16263282
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin.
    Durgam GG, Virag T, Walker MD, Tsukahara R, Yasuda S, Liliom K, van Meeteren LA, Moolenaar WH, Wilke N, Siess W, Tigyi G, Miller DD.
    J Med Chem; 2005 Jul 28; 48(15):4919-30. PubMed ID: 16033271
    [Abstract] [Full Text] [Related]

  • 4. Phosphonothioate and fluoromethylene phosphonate analogues of cyclic phosphatidic acid: Novel antagonists of lysophosphatidic acid receptors.
    Xu Y, Jiang G, Tsukahara R, Fujiwara Y, Tigyi G, Prestwich GD.
    J Med Chem; 2006 Aug 24; 49(17):5309-15. PubMed ID: 16913720
    [Abstract] [Full Text] [Related]

  • 5. Subtype-selective antagonists of lysophosphatidic Acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques.
    Rother E, Brandl R, Baker DL, Goyal P, Gebhard H, Tigyi G, Siess W.
    Circulation; 2003 Aug 12; 108(6):741-7. PubMed ID: 12885756
    [Abstract] [Full Text] [Related]

  • 6. Lysophosphatidic acid-induced platelet shape change revealed through LPA(1-5) receptor-selective probes and albumin.
    Khandoga AL, Fujiwara Y, Goyal P, Pandey D, Tsukahara R, Bolen A, Guo H, Wilke N, Liu J, Valentine WJ, Durgam GG, Miller DD, Jiang G, Prestwich GD, Tigyi G, Siess W.
    Platelets; 2008 Sep 12; 19(6):415-27. PubMed ID: 18925509
    [Abstract] [Full Text] [Related]

  • 7. Initial structure-activity relationships of lysophosphatidic acid receptor antagonists: discovery of a high-affinity LPA1/LPA3 receptor antagonist.
    Heasley BH, Jarosz R, Lynch KR, Macdonald TL.
    Bioorg Med Chem Lett; 2004 Jun 07; 14(11):2735-40. PubMed ID: 15125924
    [Abstract] [Full Text] [Related]

  • 8. Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity.
    Qian L, Xu Y, Hasegawa Y, Aoki J, Mills GB, Prestwich GD.
    J Med Chem; 2003 Dec 18; 46(26):5575-8. PubMed ID: 14667211
    [Abstract] [Full Text] [Related]

  • 9. A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3 receptor-selective antagonist.
    Heasley BH, Jarosz R, Carter KM, Van SJ, Lynch KR, Macdonald TL.
    Bioorg Med Chem Lett; 2004 Aug 02; 14(15):4069-74. PubMed ID: 15225728
    [Abstract] [Full Text] [Related]

  • 10. Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors.
    Xu Y, Tanaka M, Arai H, Aoki J, Prestwich GD.
    Bioorg Med Chem Lett; 2004 Nov 01; 14(21):5323-8. PubMed ID: 15454220
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid.
    Gupte R, Siddam A, Lu Y, Li W, Fujiwara Y, Panupinthu N, Pham TC, Baker DL, Parrill AL, Gotoh M, Murakami-Murofushi K, Kobayashi S, Mills GB, Tigyi G, Miller DD.
    Bioorg Med Chem Lett; 2010 Dec 15; 20(24):7525-8. PubMed ID: 21051230
    [Abstract] [Full Text] [Related]

  • 12. Darmstoff analogues. 3. Actions of choline esters of acetal phosphatidic acids on visceral smooth muscle.
    Marx MH, Wiley RA, Satchell DG, Maguire MH.
    J Med Chem; 1989 Jun 15; 32(6):1319-22. PubMed ID: 2724301
    [Abstract] [Full Text] [Related]

  • 13. Phosphorothioate analogues of alkyl lysophosphatidic acid as LPA3 receptor-selective agonists.
    Qian L, Xu Y, Simper T, Jiang G, Aoki J, Umezu-Goto M, Arai H, Yu S, Mills GB, Tsukahara R, Makarova N, Fujiwara Y, Tigyi G, Prestwich GD.
    ChemMedChem; 2006 Mar 15; 1(3):376-83. PubMed ID: 16892372
    [Abstract] [Full Text] [Related]

  • 14. Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist.
    McIntyre TM, Pontsler AV, Silva AR, St Hilaire A, Xu Y, Hinshaw JC, Zimmerman GA, Hama K, Aoki J, Arai H, Prestwich GD.
    Proc Natl Acad Sci U S A; 2003 Jan 07; 100(1):131-6. PubMed ID: 12502787
    [Abstract] [Full Text] [Related]

  • 15. [Cyclic phosphatidic acids and their analogues--unique lipid mediators].
    Grzelczyk A, Koziołkiewicz M.
    Postepy Biochem; 2012 Jan 07; 58(3):327-43. PubMed ID: 23373418
    [Abstract] [Full Text] [Related]

  • 16. Protean agonism of the lysophosphatidic acid receptor-1 with Ki16425 reduces nerve growth factor-induced neurite outgrowth in pheochromocytoma 12 cells.
    Moughal NA, Waters CM, Valentine WJ, Connell M, Richardson JC, Tigyi G, Pyne S, Pyne NJ.
    J Neurochem; 2006 Sep 07; 98(6):1920-9. PubMed ID: 16945108
    [Abstract] [Full Text] [Related]

  • 17. Phosphorothioate analogs of sn-2 radyl lysophosphatidic acid (LPA): metabolically stabilized LPA receptor agonists.
    Jiang G, Inoue A, Aoki J, Prestwich GD.
    Bioorg Med Chem Lett; 2013 Mar 15; 23(6):1865-9. PubMed ID: 23395664
    [Abstract] [Full Text] [Related]

  • 18. Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids.
    Waku T, Shiraki T, Oyama T, Fujimoto Y, Maebara K, Kamiya N, Jingami H, Morikawa K.
    J Mol Biol; 2009 Jan 09; 385(1):188-99. PubMed ID: 18977231
    [Abstract] [Full Text] [Related]

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