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PUBMED FOR HANDHELDS

Journal Abstract Search


182 related items for PubMed ID: 16297626

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  • 2. The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists.
    Porter DW, Bradley M, Brown Z, Charlton SJ, Cox B, Hunt P, Janus D, Lewis S, Oakley P, O'Connor D, Reilly J, Smith N, Press NJ.
    Bioorg Med Chem Lett; 2014 Aug 01; 24(15):3285-90. PubMed ID: 24974342
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  • 6. Hit-to-lead studies: the discovery of potent, orally bioavailable triazolethiol CXCR2 receptor antagonists.
    Baxter A, Bennion C, Bent J, Boden K, Brough S, Cooper A, Kinchin E, Kindon N, McInally T, Mortimore M, Roberts B, Unitt J.
    Bioorg Med Chem Lett; 2003 Aug 18; 13(16):2625-8. PubMed ID: 12873480
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  • 9. Diaminocyclobutenediones as potent and orally bioavailable CXCR2 receptor antagonists: SAR in the phenolic amide region.
    Aki C, Chao J, Ferreira JA, Dwyer MP, Yu Y, Chao J, Merritt RJ, Lai G, Wu M, Hipkin RW, Fan X, Gonsiorek W, Fosseta J, Rindgen D, Fine J, Lundell D, Taveras AG, Biju P.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4446-9. PubMed ID: 19525110
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  • 13. Discovery of imidazole vinyl pyrimidines as a novel class of kinase inhibitors which inhibit Tie-2 and are orally bioavailable.
    Buttar D, Edge M, Emery SC, Fitzek M, Forder C, Griffen A, Hayter B, Hayward CF, Hopcroft PJ, Luke RW, Page K, Stawpert J, Wright A.
    Bioorg Med Chem Lett; 2008 Aug 15; 18(16):4723-6. PubMed ID: 18676144
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  • 16. Potent achiral agonists of the growth hormone secretagogue (ghrelin) receptor. Part 2: Lead optimisation.
    Witherington J, Abberley L, Briggs MA, Collis K, Dean DK, Gaiba A, King NP, Kraus H, Shuker N, Steadman JG, Takle AK, Sanger G, Wadsworth G, Butler S, McKay F, Muir A, Winborn K, Heightman TD.
    Bioorg Med Chem Lett; 2008 Mar 15; 18(6):2203-5. PubMed ID: 18316188
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  • 19. Evaluation of a series of bicyclic CXCR2 antagonists.
    Walters I, Austin C, Austin R, Bonnert R, Cage P, Christie M, Ebden M, Gardiner S, Grahames C, Hill S, Hunt F, Jewell R, Lewis S, Martin I, David Nicholls, David Robinson.
    Bioorg Med Chem Lett; 2008 Jan 15; 18(2):798-803. PubMed ID: 18240390
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  • 20. C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists.
    Chao J, Taveras AG, Chao J, Aki C, Dwyer M, Yu Y, Purakkattle B, Rindgen D, Jakway J, Hipkin W, Fosetta J, Fan X, Lundell D, Fine J, Minnicozzi M, Phillips J, Merritt JR.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3778-83. PubMed ID: 17459706
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