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125 related items for PubMed ID: 16313189
1. Structure-based identification of the binding site for the hemiasterlin analogue HTI-286 on tubulin. Ravi M, Zask A, Rush TS. Biochemistry; 2005 Dec 06; 44(48):15871-9. PubMed ID: 16313189 [Abstract] [Full Text] [Related]
6. Tumor cells resistant to a microtubule-depolymerizing hemiasterlin analogue, HTI-286, have mutations in alpha- or beta-tubulin and increased microtubule stability. Poruchynsky MS, Kim JH, Nogales E, Annable T, Loganzo F, Greenberger LM, Sackett DL, Fojo T. Biochemistry; 2004 Nov 09; 43(44):13944-54. PubMed ID: 15518543 [Abstract] [Full Text] [Related]
7. The tubulin-bound structure of the antimitotic drug tubulysin. Kubicek K, Grimm SK, Orts J, Sasse F, Carlomagno T. Angew Chem Int Ed Engl; 2010 Jun 28; 49(28):4809-12. PubMed ID: 20496362 [No Abstract] [Full Text] [Related]
9. Localization of the antimitotic peptide and depsipeptide binding site on beta-tubulin. Mitra A, Sept D. Biochemistry; 2004 Nov 09; 43(44):13955-62. PubMed ID: 15518544 [Abstract] [Full Text] [Related]
10. Absolute configurations of tubulin inhibitors taltobulin (HTI-286) and HTI-042 characterized by X-ray diffraction analysis and NMR studies. Niu C, Ho DM, Williamson RT, Zask A, Ayral-Kaloustian S. Bioorg Med Chem Lett; 2010 Mar 01; 20(5):1535-8. PubMed ID: 20137930 [Abstract] [Full Text] [Related]
11. The betaI/betaIII-tubulin isoforms and their complexes with antimitotic agents. Docking and molecular dynamics studies. Magnani M, Ortuso F, Soro S, Alcaro S, Tramontano A, Botta M. FEBS J; 2006 Jul 01; 273(14):3301-10. PubMed ID: 16803461 [Abstract] [Full Text] [Related]
13. Synthesis and biological activity of analogues of the antimicrotubule agent N,beta,beta-trimethyl-L-phenylalanyl-N(1)-[(1S,2E)-3-carboxy-1-isopropylbut-2-enyl]- N(1),3-dimethyl-L-valinamide (HTI-286). Zask A, Birnberg G, Cheung K, Kaplan J, Niu C, Norton E, Suayan R, Yamashita A, Cole D, Tang Z, Krishnamurthy G, Williamson R, Khafizova G, Musto S, Hernandez R, Annable T, Yang X, Discafani C, Beyer C, Greenberger LM, Loganzo F, Ayral-Kaloustian S. J Med Chem; 2004 Sep 09; 47(19):4774-86. PubMed ID: 15341492 [Abstract] [Full Text] [Related]
14. Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines. Ouyang X, Piatnitski EL, Pattaropong V, Chen X, He HY, Kiselyov AS, Velankar A, Kawakami J, Labelle M, Smith L, Lohman J, Lee SP, Malikzay A, Fleming J, Gerlak J, Wang Y, Rosler RL, Zhou K, Mitelman S, Camara M, Surguladze D, Doody JF, Tuma MC. Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1191-6. PubMed ID: 16377187 [Abstract] [Full Text] [Related]
15. Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria. Khalil MW, Sasse F, Lünsdorf H, Elnakady YA, Reichenbach H. Chembiochem; 2006 Apr 01; 7(4):678-83. PubMed ID: 16491500 [Abstract] [Full Text] [Related]
16. The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography. Nettles JH, Li H, Cornett B, Krahn JM, Snyder JP, Downing KH. Science; 2004 Aug 06; 305(5685):866-9. PubMed ID: 15297674 [Abstract] [Full Text] [Related]
17. The binding of vinca domain agents to tubulin: structural and biochemical studies. Cormier A, Knossow M, Wang C, Gigant B. Methods Cell Biol; 2010 Aug 06; 95():373-90. PubMed ID: 20466145 [Abstract] [Full Text] [Related]
18. A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin. Xia S, Kenesky CS, Rucker PV, Smith AB, Orr GA, Horwitz SB. Biochemistry; 2006 Oct 03; 45(39):11762-75. PubMed ID: 17002277 [Abstract] [Full Text] [Related]
19. Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin. Kuznetsov G, TenDyke K, Towle MJ, Cheng H, Liu J, Marsh JP, Schiller SE, Spyvee MR, Yang H, Seletsky BM, Shaffer CJ, Marceau V, Yao Y, Suh EM, Campagna S, Fang FG, Kowalczyk JJ, Littlefield BA. Mol Cancer Ther; 2009 Oct 03; 8(10):2852-60. PubMed ID: 19825803 [Abstract] [Full Text] [Related]
20. Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors. Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Hsieh HP, Hamel E. J Med Chem; 2008 Mar 13; 51(5):1464-8. PubMed ID: 18260616 [Abstract] [Full Text] [Related] Page: [Next] [New Search]