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Journal Abstract Search


423 related items for PubMed ID: 16317705

  • 1. Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes.
    Dent P, Fang Y, Gupta S, Studer E, Mitchell C, Spiegel S, Hylemon PB.
    Hepatology; 2005 Dec; 42(6):1291-9. PubMed ID: 16317705
    [Abstract] [Full Text] [Related]

  • 2. Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes.
    Fang Y, Han SI, Mitchell C, Gupta S, Studer E, Grant S, Hylemon PB, Dent P.
    Hepatology; 2004 Oct; 40(4):961-71. PubMed ID: 15382121
    [Abstract] [Full Text] [Related]

  • 3. Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.
    Studer E, Zhou X, Zhao R, Wang Y, Takabe K, Nagahashi M, Pandak WM, Dent P, Spiegel S, Shi R, Xu W, Liu X, Bohdan P, Zhang L, Zhou H, Hylemon PB.
    Hepatology; 2012 Jan; 55(1):267-76. PubMed ID: 21932398
    [Abstract] [Full Text] [Related]

  • 4. Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes.
    Rao YP, Studer EJ, Stravitz RT, Gupta S, Qiao L, Dent P, Hylemon PB.
    Hepatology; 2002 Feb; 35(2):307-14. PubMed ID: 11826403
    [Abstract] [Full Text] [Related]

  • 5. Tauroursodeoxycholic acid protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways.
    Schoemaker MH, Conde de la Rosa L, Buist-Homan M, Vrenken TE, Havinga R, Poelstra K, Haisma HJ, Jansen PL, Moshage H.
    Hepatology; 2004 Jun; 39(6):1563-73. PubMed ID: 15185297
    [Abstract] [Full Text] [Related]

  • 6. Bile acids enhance the activity of the insulin receptor and glycogen synthase in primary rodent hepatocytes.
    Han SI, Studer E, Gupta S, Fang Y, Qiao L, Li W, Grant S, Hylemon PB, Dent P.
    Hepatology; 2004 Feb; 39(2):456-63. PubMed ID: 14767998
    [Abstract] [Full Text] [Related]

  • 7. Pertussis toxin, an inhibitor of G(αi) PCR, inhibits bile acid- and cytokine-induced apoptosis in primary rat hepatocytes.
    Karimian G, Buist-Homan M, Faber KN, Moshage H.
    PLoS One; 2012 Feb; 7(8):e43156. PubMed ID: 22900098
    [Abstract] [Full Text] [Related]

  • 8. Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53.
    Qiao L, McKinstry R, Gupta S, Gilfor D, Windle JJ, Hylemon PB, Grant S, Fisher PB, Dent P.
    Hepatology; 2002 Jul; 36(1):39-48. PubMed ID: 12085347
    [Abstract] [Full Text] [Related]

  • 9. Betagamma subunits of G(i/o) suppress EGF-induced ERK5 phosphorylation, whereas ERK1/2 phosphorylation is enhanced.
    Obara Y, Okano Y, Ono S, Yamauchi A, Hoshino T, Kurose H, Nakahata N.
    Cell Signal; 2008 Jul; 20(7):1275-83. PubMed ID: 18407464
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of insulin/IGF-1 receptor signaling enhances bile acid toxicity in primary hepatocytes.
    Dent P, Han SI, Mitchell C, Studer E, Yacoub A, Grandis J, Grant S, Krystal GW, Hylemon PB.
    Biochem Pharmacol; 2005 Nov 25; 70(11):1685-96. PubMed ID: 16207485
    [Abstract] [Full Text] [Related]

  • 11. Acetoacetate activation of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in primary cultured rat hepatocytes: role of oxidative stress.
    Abdelmegeed MA, Kim SK, Woodcroft KJ, Novak RF.
    J Pharmacol Exp Ther; 2004 Aug 25; 310(2):728-36. PubMed ID: 15051799
    [Abstract] [Full Text] [Related]

  • 12. Farnesoid X receptor activation by chenodeoxycholic acid induces detoxifying enzymes through AMP-activated protein kinase and extracellular signal-regulated kinase 1/2-mediated phosphorylation of CCAAT/enhancer binding protein β.
    Noh K, Kim YM, Kim YW, Kim SG.
    Drug Metab Dispos; 2011 Aug 25; 39(8):1451-9. PubMed ID: 21596890
    [Abstract] [Full Text] [Related]

  • 13. Toxicity and intracellular accumulation of bile acids in sandwich-cultured rat hepatocytes: role of glycine conjugates.
    Chatterjee S, Bijsmans IT, van Mil SW, Augustijns P, Annaert P.
    Toxicol In Vitro; 2014 Mar 25; 28(2):218-30. PubMed ID: 24211540
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes.
    Qiao L, Yacoub A, Studer E, Gupta S, Pei XY, Grant S, Hylemon PB, Dent P.
    Hepatology; 2002 Apr 25; 35(4):779-89. PubMed ID: 11915023
    [Abstract] [Full Text] [Related]

  • 15. Pregnane X receptor activation protects rat hepatocytes against deoxycholic acid-induced apoptosis.
    Zucchini-Pascal N, de Sousa G, Pizzol J, Rahmani R.
    Liver Int; 2010 Feb 25; 30(2):284-97. PubMed ID: 19737350
    [Abstract] [Full Text] [Related]

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  • 17. Chenodeoxycholic acid and taurochenodexycholic acid induce anti-apoptotic cIAP-1 expression in human hepatocytes.
    Hirano F, Haneda M, Makino I.
    J Gastroenterol Hepatol; 2006 Dec 25; 21(12):1807-13. PubMed ID: 17074018
    [Abstract] [Full Text] [Related]

  • 18. Control of PDGF-induced reactive oxygen species (ROS) generation and signal transduction in human lens epithelial cells.
    Chen KC, Zhou Y, Zhang W, Lou MF.
    Mol Vis; 2007 Mar 14; 13():374-87. PubMed ID: 17392688
    [Abstract] [Full Text] [Related]

  • 19. Conjugated bile acids regulate hepatocyte glycogen synthase activity in vitro and in vivo via Galphai signaling.
    Fang Y, Studer E, Mitchell C, Grant S, Pandak WM, Hylemon PB, Dent P.
    Mol Pharmacol; 2007 Apr 14; 71(4):1122-8. PubMed ID: 17200418
    [Abstract] [Full Text] [Related]

  • 20. L-leucine increases [3H]-thymidine incorporation in chicken hepatocytes: involvement of the PKC, PI3K/Akt, ERK1/2, and mTOR signaling pathways.
    Lee MY, Jo SD, Lee JH, Han HJ.
    J Cell Biochem; 2008 Dec 15; 105(6):1410-9. PubMed ID: 18980246
    [Abstract] [Full Text] [Related]


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