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Journal Abstract Search

222 related items for PubMed ID: 16335921

  • 1. Further structure-activity relationship studies of piperidine-based monoamine transporter inhibitors: effects of piperidine ring stereochemistry on potency. Identification of norepinephrine transporter selective ligands and broad-spectrum transporter inhibitors.
    He R, Kurome T, Giberson KM, Johnson KM, Kozikowski AP.
    J Med Chem; 2005 Dec 15; 48(25):7970-9. PubMed ID: 16335921
    [Abstract] [Full Text] [Related]

  • 2. Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors.
    Tamiz AP, Zhang J, Flippen-Anderson JL, Zhang M, Johnson KM, Deschaux O, Tella S, Kozikowski AP.
    J Med Chem; 2000 Mar 23; 43(6):1215-22. PubMed ID: 10737754
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  • 3. Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity.
    Greiner E, Boos TL, Prisinzano TE, De Martino MG, Zeglis B, Dersch CM, Marcus J, Partilla JS, Rothman RB, Jacobson AE, Rice KC.
    J Med Chem; 2006 Mar 09; 49(5):1766-72. PubMed ID: 16509591
    [Abstract] [Full Text] [Related]

  • 4. Further studies on conformationally constrained tricyclic tropane analogues and their uptake inhibition at monoamine transporter sites: synthesis of (Z)-9-(substituted arylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes as a novel class of serotonin transporter inhibitors.
    Zhang A, Zhou G, Hoepping A, Mukhopadhyaya J, Johnson KM, Zhang M, Kozikowski AP.
    J Med Chem; 2002 Apr 25; 45(9):1930-41. PubMed ID: 11960503
    [Abstract] [Full Text] [Related]

  • 5. Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors.
    Tamiz AP, Bandyopadhyay BC, Zhang J, Flippen-Anderson JL, Zhang M, Wang CZ, Johnson KM, Tella S, Kozikowski AP.
    J Med Chem; 2001 May 10; 44(10):1615-22. PubMed ID: 11334571
    [Abstract] [Full Text] [Related]

  • 6. Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters.
    Kolhatkar R, Cook CD, Ghorai SK, Deschamps J, Beardsley PM, Reith ME, Dutta AK.
    J Med Chem; 2004 Oct 07; 47(21):5101-13. PubMed ID: 15456254
    [Abstract] [Full Text] [Related]

  • 7. Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.
    Orjales A, Mosquera R, Toledo A, Pumar MC, García N, Cortizo L, Labeaga L, Innerárity A.
    J Med Chem; 2003 Dec 04; 46(25):5512-32. PubMed ID: 14640559
    [Abstract] [Full Text] [Related]

  • 8. Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization.
    Zhou J, He R, Johnson KM, Ye Y, Kozikowski AP.
    J Med Chem; 2004 Nov 18; 47(24):5821-4. PubMed ID: 15537337
    [Abstract] [Full Text] [Related]

  • 9. Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.
    Kolhatkar RB, Ghorai SK, George C, Reith ME, Dutta AK.
    J Med Chem; 2003 May 22; 46(11):2205-15. PubMed ID: 12747792
    [Abstract] [Full Text] [Related]

  • 10. D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action.
    Dutta AK, Ghosh B, Biswas S, Reith ME.
    Eur J Pharmacol; 2008 Jul 28; 589(1-3):73-9. PubMed ID: 18561912
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  • 13. SAR studies of piperidine-based analogues of cocaine. 4. Effect of N-modification and ester replacement.
    Petukhov PA, Zhang J, Kozikowski AP, Wang CZ, Ye YP, Johnson KM, Tella SR.
    J Med Chem; 2002 Jul 18; 45(15):3161-70. PubMed ID: 12109901
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  • 14. Structure-activity relationships for a novel series of citalopram (1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) analogues at monoamine transporters.
    Zhang P, Cyriac G, Kopajtic T, Zhao Y, Javitch JA, Katz JL, Newman AH.
    J Med Chem; 2010 Aug 26; 53(16):6112-21. PubMed ID: 20672825
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  • 15. Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.
    Dutta AK, Fei XS, Beardsley PM, Newman JL, Reith ME.
    J Med Chem; 2001 Mar 15; 44(6):937-48. PubMed ID: 11300876
    [Abstract] [Full Text] [Related]

  • 16. Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter.
    Hoepping A, Johnson KM, George C, Flippen-Anderson J, Kozikowski AP.
    J Med Chem; 2000 May 18; 43(10):2064-71. PubMed ID: 10821718
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  • 18. Synthesis, monoamine transporter binding, properties, and functional monoamine uptake activity of 3beta-[4-methylphenyl and 4-chlorophenyl]-2 beta-[5-(substituted phenyl)thiazol-2-yl]tropanes.
    Gong PK, Blough BE, Brieaddy LE, Huang X, Kuhar MJ, Navarro HA, Carroll FI.
    J Med Chem; 2007 Jul 26; 50(15):3686-95. PubMed ID: 17602602
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  • 20. Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone.
    McLaughlin G, Morris N, Kavanagh PV, Power JD, Dowling G, Twamley B, O'Brien J, Talbot B, Walther D, Partilla JS, Baumann MH, Brandt SD.
    Drug Test Anal; 2017 Mar 26; 9(3):358-368. PubMed ID: 27524685
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