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373 related items for PubMed ID: 16354697

  • 1. Focal adhesion kinase is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA.
    Tsutsumi R, Takahashi A, Azuma T, Higashi H, Hatakeyama M.
    Mol Cell Biol; 2006 Jan; 26(1):261-76. PubMed ID: 16354697
    [Abstract] [Full Text] [Related]

  • 2. The CagA protein of Helicobacter pylori is translocated into epithelial cells and binds to SHP-2 in human gastric mucosa.
    Yamazaki S, Yamakawa A, Ito Y, Ohtani M, Higashi H, Hatakeyama M, Azuma T.
    J Infect Dis; 2003 Jan 15; 187(2):334-7. PubMed ID: 12552462
    [Abstract] [Full Text] [Related]

  • 3. Influence of EPIYA-repeat polymorphism on the phosphorylation-dependent biological activity of Helicobacter pylori CagA.
    Naito M, Yamazaki T, Tsutsumi R, Higashi H, Onoe K, Yamazaki S, Azuma T, Hatakeyama M.
    Gastroenterology; 2006 Apr 15; 130(4):1181-90. PubMed ID: 16618412
    [Abstract] [Full Text] [Related]

  • 4. Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity.
    Saadat I, Higashi H, Obuse C, Umeda M, Murata-Kamiya N, Saito Y, Lu H, Ohnishi N, Azuma T, Suzuki A, Ohno S, Hatakeyama M.
    Nature; 2007 May 17; 447(7142):330-3. PubMed ID: 17507984
    [Abstract] [Full Text] [Related]

  • 5. Attenuation of Helicobacter pylori CagA x SHP-2 signaling by interaction between CagA and C-terminal Src kinase.
    Tsutsumi R, Higashi H, Higuchi M, Okada M, Hatakeyama M.
    J Biol Chem; 2003 Feb 07; 278(6):3664-70. PubMed ID: 12446738
    [Abstract] [Full Text] [Related]

  • 6. Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion.
    Suzuki M, Mimuro H, Suzuki T, Park M, Yamamoto T, Sasakawa C.
    J Exp Med; 2005 Nov 07; 202(9):1235-47. PubMed ID: 16275761
    [Abstract] [Full Text] [Related]

  • 7. CagA phosphorylation-dependent MMP-9 expression in gastric epithelial cells.
    Nam YH, Ryu E, Lee D, Shim HJ, Lee YC, Lee ST.
    Helicobacter; 2011 Aug 07; 16(4):276-83. PubMed ID: 21762266
    [Abstract] [Full Text] [Related]

  • 8. The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation.
    Selbach M, Moese S, Hurwitz R, Hauck CR, Meyer TF, Backert S.
    EMBO J; 2003 Feb 03; 22(3):515-28. PubMed ID: 12554652
    [Abstract] [Full Text] [Related]

  • 9. SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein.
    Higashi H, Tsutsumi R, Muto S, Sugiyama T, Azuma T, Asaka M, Hatakeyama M.
    Science; 2002 Jan 25; 295(5555):683-6. PubMed ID: 11743164
    [Abstract] [Full Text] [Related]

  • 10. Helicobacter pylori CagA -- a bacterial intruder conspiring gastric carcinogenesis.
    Hatakeyama M.
    Int J Cancer; 2006 Sep 15; 119(6):1217-23. PubMed ID: 16557568
    [Abstract] [Full Text] [Related]

  • 11. Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation.
    Higashi H, Nakaya A, Tsutsumi R, Yokoyama K, Fujii Y, Ishikawa S, Higuchi M, Takahashi A, Kurashima Y, Teishikata Y, Tanaka S, Azuma T, Hatakeyama M.
    J Biol Chem; 2004 Apr 23; 279(17):17205-16. PubMed ID: 14963045
    [Abstract] [Full Text] [Related]

  • 12. Deregulation of SHP-2 tyrosine phosphatase by the Helicobacter pylori virulence factor CagA.
    Hatakeyama M.
    Keio J Med; 2002 Dec 23; 51 Suppl 2():26-32. PubMed ID: 12528933
    [Abstract] [Full Text] [Related]

  • 13. EPIYA motif is a membrane-targeting signal of Helicobacter pylori virulence factor CagA in mammalian cells.
    Higashi H, Yokoyama K, Fujii Y, Ren S, Yuasa H, Saadat I, Murata-Kamiya N, Azuma T, Hatakeyama M.
    J Biol Chem; 2005 Jun 17; 280(24):23130-7. PubMed ID: 15831497
    [Abstract] [Full Text] [Related]

  • 14. The effects of cure of Helicobacter pylori infection on the signal transduction of gastric epithelial cells.
    Azuma T, Yamazaki S, Yamakawa A, Ito Y, Ohtani M, Dojo M, Yamazaki Y, Higashi H, Hatakeyama M.
    Aliment Pharmacol Ther; 2003 Jul 17; 18 Suppl 1():39-44. PubMed ID: 12925139
    [Abstract] [Full Text] [Related]

  • 15. Helicobacter pylori CagA interacts with E-cadherin and deregulates the beta-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells.
    Murata-Kamiya N, Kurashima Y, Teishikata Y, Yamahashi Y, Saito Y, Higashi H, Aburatani H, Akiyama T, Peek RM, Azuma T, Hatakeyama M.
    Oncogene; 2007 Jul 12; 26(32):4617-26. PubMed ID: 17237808
    [Abstract] [Full Text] [Related]

  • 16. Phosphorylation of Helicobacter pylori CagA by c-Abl leads to cell motility.
    Poppe M, Feller SM, Römer G, Wessler S.
    Oncogene; 2007 May 24; 26(24):3462-72. PubMed ID: 17160020
    [Abstract] [Full Text] [Related]

  • 17. Interaction between the Helicobacter pylori CagA and alpha-Pix in gastric epithelial AGS cells.
    Baek HY, Lim JW, Kim H.
    Ann N Y Acad Sci; 2007 Jan 24; 1096():18-23. PubMed ID: 17405911
    [Abstract] [Full Text] [Related]

  • 18. Orchestration of aberrant epithelial signaling by Helicobacter pylori CagA.
    Peek RM.
    Sci STKE; 2005 Mar 29; 2005(277):pe14. PubMed ID: 15798102
    [Abstract] [Full Text] [Related]

  • 19. Activation of Abl by Helicobacter pylori: a novel kinase for CagA and crucial mediator of host cell scattering.
    Tammer I, Brandt S, Hartig R, König W, Backert S.
    Gastroenterology; 2007 Apr 29; 132(4):1309-19. PubMed ID: 17408661
    [Abstract] [Full Text] [Related]

  • 20. Oncogenic mechanisms of the Helicobacter pylori CagA protein.
    Hatakeyama M.
    Nat Rev Cancer; 2004 Sep 29; 4(9):688-94. PubMed ID: 15343275
    [Abstract] [Full Text] [Related]

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