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99 related items for PubMed ID: 16354762

  • 1. How batrachotoxin modifies the sodium channel permeation pathway: computer modeling and site-directed mutagenesis.
    Wang SY, Mitchell J, Tikhonov DB, Zhorov BS, Wang GK.
    Mol Pharmacol; 2006 Mar; 69(3):788-95. PubMed ID: 16354762
    [Abstract] [Full Text] [Related]

  • 2. Serine-401 as a batrachotoxin- and local anesthetic-sensing residue in the human cardiac Na+ channel.
    Wang SY, Tikhonov DB, Zhorov BS, Mitchell J, Wang GK.
    Pflugers Arch; 2007 May; 454(2):277-87. PubMed ID: 17205354
    [Abstract] [Full Text] [Related]

  • 3. A phenylalanine residue at segment D3-S6 in Nav1.4 voltage-gated Na(+) channels is critical for pyrethroid action.
    Wang SY, Barile M, Wang GK.
    Mol Pharmacol; 2001 Sep; 60(3):620-8. PubMed ID: 11502895
    [Abstract] [Full Text] [Related]

  • 4. Irreversible block of cardiac mutant Na+ channels by batrachotoxin.
    Wang SY, Tikhonov DB, Mitchell J, Zhorov BS, Wang GK.
    Channels (Austin); 2007 Sep; 1(3):179-88. PubMed ID: 18690024
    [Abstract] [Full Text] [Related]

  • 5. Residues in Na(+) channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities.
    Wang SY, Nau C, Wang GK.
    Biophys J; 2000 Sep; 79(3):1379-87. PubMed ID: 10969000
    [Abstract] [Full Text] [Related]

  • 6. Disparate role of Na(+) channel D2-S6 residues in batrachotoxin and local anesthetic action.
    Wang SY, Barile M, Wang GK.
    Mol Pharmacol; 2001 May; 59(5):1100-7. PubMed ID: 11306693
    [Abstract] [Full Text] [Related]

  • 7. Point mutations in segment I-S6 render voltage-gated Na+ channels resistant to batrachotoxin.
    Wang SY, Wang GK.
    Proc Natl Acad Sci U S A; 1998 Mar 03; 95(5):2653-8. PubMed ID: 9482942
    [Abstract] [Full Text] [Related]

  • 8. Batrachotoxin-resistant Na+ channels derived from point mutations in transmembrane segment D4-S6.
    Wang SY, Wang GK.
    Biophys J; 1999 Jun 03; 76(6):3141-9. PubMed ID: 10354438
    [Abstract] [Full Text] [Related]

  • 9. The batrachotoxin receptor on the voltage-gated sodium channel is guarded by the channel activation gate.
    Li HL, Hadid D, Ragsdale DS.
    Mol Pharmacol; 2002 Apr 03; 61(4):905-12. PubMed ID: 11901230
    [Abstract] [Full Text] [Related]

  • 10. Altered stereoselectivity of cocaine and bupivacaine isomers in normal and batrachotoxin-modified Na+ channels.
    Wang GK, Wang SY.
    J Gen Physiol; 1992 Dec 03; 100(6):1003-20. PubMed ID: 1336539
    [Abstract] [Full Text] [Related]

  • 11. Time-dependent block and resurgent tail currents induced by mouse beta4(154-167) peptide in cardiac Na+ channels.
    Wang GK, Edrich T, Wang SY.
    J Gen Physiol; 2006 Mar 03; 127(3):277-89. PubMed ID: 16505148
    [Abstract] [Full Text] [Related]

  • 12. Point mutations at L1280 in Nav1.4 channel D3-S6 modulate binding affinity and stereoselectivity of bupivacaine enantiomers.
    Nau C, Wang SY, Wang GK.
    Mol Pharmacol; 2003 Jun 03; 63(6):1398-406. PubMed ID: 12761351
    [Abstract] [Full Text] [Related]

  • 13. Veratridine block of rat skeletal muscle Nav1.4 sodium channels in the inner vestibule.
    Wang GK, Wang SY.
    J Physiol; 2003 May 01; 548(Pt 3):667-75. PubMed ID: 12626674
    [Abstract] [Full Text] [Related]

  • 14. Tryptophan substitution of a putative D4S6 gating hinge alters slow inactivation in cardiac sodium channels.
    Wang SY, Russell C, Wang GK.
    Biophys J; 2005 Jun 01; 88(6):3991-9. PubMed ID: 15805167
    [Abstract] [Full Text] [Related]

  • 15. Structural determinants of quaternary ammonium blockers for batrachotoxin-modified Na+ channels.
    Wang GK, Simon R, Bell D, Mok WM, Wang SY.
    Mol Pharmacol; 1993 Sep 01; 44(3):667-76. PubMed ID: 8396721
    [Abstract] [Full Text] [Related]

  • 16. Single rat muscle Na+ channel mutation confers batrachotoxin autoresistance found in poison-dart frog Phyllobates terribilis.
    Wang SY, Wang GK.
    Proc Natl Acad Sci U S A; 2017 Sep 26; 114(39):10491-10496. PubMed ID: 28874544
    [Abstract] [Full Text] [Related]

  • 17. An inner pore residue (Asn406) in the Nav1.5 channel controls slow inactivation and enhances mibefradil block to T-type Ca2+ channel levels.
    McNulty MM, Kyle JW, Lipkind GM, Hanck DA.
    Mol Pharmacol; 2006 Nov 26; 70(5):1514-23. PubMed ID: 16885209
    [Abstract] [Full Text] [Related]

  • 18. Modification of cardiac Na+ channels by batrachotoxin: effects on gating, kinetics, and local anesthetic binding.
    Wasserstrom JA, Liberty K, Kelly J, Santucci P, Myers M.
    Biophys J; 1993 Jul 26; 65(1):386-95. PubMed ID: 8396458
    [Abstract] [Full Text] [Related]

  • 19. A tryptophan residue (W736) in the amino-terminus of the P-segment of domain II is involved in pore formation in Na(v)1.4 voltage-gated sodium channels.
    Carbonneau E, Vijayaragavan K, Chahine M.
    Pflugers Arch; 2002 Oct 26; 445(1):18-24. PubMed ID: 12397382
    [Abstract] [Full Text] [Related]

  • 20. State-dependent access to the batrachotoxin receptor on the sodium channel.
    De Leon L, Ragsdale DS.
    Neuroreport; 2003 Jul 18; 14(10):1353-6. PubMed ID: 12876472
    [Abstract] [Full Text] [Related]

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