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186 related items for PubMed ID: 16357944

  • 1. Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations.
    Nakada S, Katsuki Y, Imoto I, Yokoyama T, Nagasawa M, Inazawa J, Mizutani S.
    J Clin Invest; 2006 Jan; 116(1):80-9. PubMed ID: 16357944
    [Abstract] [Full Text] [Related]

  • 2. MLL rearrangements are induced by low doses of etoposide in human fetal hematopoietic stem cells.
    Moneypenny CG, Shao J, Song Y, Gallagher EP.
    Carcinogenesis; 2006 Apr; 27(4):874-81. PubMed ID: 16377807
    [Abstract] [Full Text] [Related]

  • 3. Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11).
    Domer PH, Head DR, Renganathan N, Raimondi SC, Yang E, Atlas M.
    Leukemia; 1995 Aug; 9(8):1305-12. PubMed ID: 7643617
    [Abstract] [Full Text] [Related]

  • 4. The broken MLL gene is frequently located outside the inherent chromosome territory in human lymphoid cells treated with DNA topoisomerase II poison etoposide.
    Glukhov SI, Rubtsov MA, Alexeyevsky DA, Alexeevski AV, Razin SV, Iarovaia OV.
    PLoS One; 2013 Aug; 8(9):e75871. PubMed ID: 24086652
    [Abstract] [Full Text] [Related]

  • 5. Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions.
    Sung PA, Libura J, Richardson C.
    DNA Repair (Amst); 2006 Sep 08; 5(9-10):1109-18. PubMed ID: 16809075
    [Abstract] [Full Text] [Related]

  • 6. ATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot.
    Sun J, Oma Y, Harata M, Kono K, Shima H, Kinomura A, Ikura T, Suzuki H, Mizutani S, Kanaar R, Tashiro S.
    PLoS One; 2010 Oct 27; 5(10):e13554. PubMed ID: 21048951
    [Abstract] [Full Text] [Related]

  • 7. [Combination of interphase- and metaphase-fluorescence in situ hybridization to identify 11q23/MLL abnormalities in acute leukemia patients].
    Zhao XC, Li CW, Dai Y, Liu XP, Qin S, Liu SH, Mi YC, Wang JX.
    Zhonghua Xue Ye Xue Za Zhi; 2006 Oct 27; 27(10):682-6. PubMed ID: 17343201
    [Abstract] [Full Text] [Related]

  • 8. The MLL gene and translocations involving chromosomal band 11q23 in acute leukemia.
    De Braekeleer M, Morel F, Le Bris MJ, Herry A, Douet-Guilbert N.
    Anticancer Res; 2005 Oct 27; 25(3B):1931-44. PubMed ID: 16158928
    [Abstract] [Full Text] [Related]

  • 9. Leukaemia-specific chromosome damage detected by comet with fluorescence in situ hybridization (comet-FISH).
    Escobar PA, Smith MT, Vasishta A, Hubbard AE, Zhang L.
    Mutagenesis; 2007 Sep 27; 22(5):321-7. PubMed ID: 17575318
    [Abstract] [Full Text] [Related]

  • 10. Detection of 11q23/MLL rearrangements in infant leukemias with fluorescence in situ hybridization and molecular analysis.
    Martinez-Climent JA, Thirman MJ, Espinosa R, Le Beau MM, Rowley JD.
    Leukemia; 1995 Aug 27; 9(8):1299-304. PubMed ID: 7643616
    [Abstract] [Full Text] [Related]

  • 11. Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint.
    Liu H, Takeda S, Kumar R, Westergard TD, Brown EJ, Pandita TK, Cheng EH, Hsieh JJ.
    Nature; 2010 Sep 16; 467(7313):343-6. PubMed ID: 20818375
    [Abstract] [Full Text] [Related]

  • 12. Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity.
    Cowell IG, Sondka Z, Smith K, Lee KC, Manville CM, Sidorczuk-Lesthuruge M, Rance HA, Padget K, Jackson GH, Adachi N, Austin CA.
    Proc Natl Acad Sci U S A; 2012 Jun 05; 109(23):8989-94. PubMed ID: 22615413
    [Abstract] [Full Text] [Related]

  • 13. Pediatric T-cell acute lymphoblastic leukemia with aberrations of both MLL loci.
    Quigley DI, Wolff DJ.
    Cancer Genet Cytogenet; 2006 Jul 01; 168(1):77-9. PubMed ID: 16772125
    [Abstract] [Full Text] [Related]

  • 14. Rearrangements involving chromosome band 11Q23 in acute leukaemia.
    Rowley JD.
    Semin Cancer Biol; 1993 Dec 01; 4(6):377-85. PubMed ID: 8142623
    [Abstract] [Full Text] [Related]

  • 15. Three-way translocation involving MLL, MLLT1, and a novel third partner, NRXN1, in a patient with acute lymphoblastic leukemia and t(2;19;11) (p12;p13.3;q23).
    Lee SG, Park TS, Won SC, Song J, Lee KA, Choi JR, Marschalek R, Meyer C.
    Cancer Genet Cytogenet; 2010 Feb 01; 197(1):32-8. PubMed ID: 20113834
    [Abstract] [Full Text] [Related]

  • 16. Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.
    Lovett BD, Strumberg D, Blair IA, Pang S, Burden DA, Megonigal MD, Rappaport EF, Rebbeck TR, Osheroff N, Pommier YG, Felix CA.
    Biochemistry; 2001 Feb 06; 40(5):1159-70. PubMed ID: 11170441
    [Abstract] [Full Text] [Related]

  • 17. Application of fluorescence in situ hybridisation to study the relationship between cytotoxicity, chromosome aberrations, and changes in chromosome number after treatment with the topoisomerase II inhibitor amsacrine.
    Ferguson LR, Whiteside G, Holdaway KM, Baguley BC.
    Environ Mol Mutagen; 1996 Feb 06; 27(4):255-62. PubMed ID: 8665870
    [Abstract] [Full Text] [Related]

  • 18. Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors.
    Megonigal MD, Cheung NK, Rappaport EF, Nowell PC, Wilson RB, Jones DH, Addya K, Leonard DG, Kushner BH, Williams TM, Lange BJ, Felix CA.
    Proc Natl Acad Sci U S A; 2000 Mar 14; 97(6):2814-9. PubMed ID: 10706619
    [Abstract] [Full Text] [Related]

  • 19. Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations.
    Drexler HG, Quentmeier H, MacLeod RA.
    Leukemia; 2004 Feb 14; 18(2):227-32. PubMed ID: 14671638
    [Abstract] [Full Text] [Related]

  • 20. Cloning of cDNAs of the MLL gene that detect DNA rearrangements and altered RNA transcripts in human leukemic cells with 11q23 translocations.
    McCabe NR, Burnett RC, Gill HJ, Thirman MJ, Mbangkollo D, Kipiniak M, van Melle E, Ziemin-van der Poel S, Rowley JD, Diaz MO.
    Proc Natl Acad Sci U S A; 1992 Dec 15; 89(24):11794-8. PubMed ID: 1465401
    [Abstract] [Full Text] [Related]


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