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Journal Abstract Search


226 related items for PubMed ID: 16359169

  • 1. Identification of N-(hydroxymethyl) norcotinine as a major product of cytochrome P450 2A6, but not cytochrome P450 2A13-catalyzed cotinine metabolism.
    Brown KM, von Weymarn LB, Murphy SE.
    Chem Res Toxicol; 2005 Dec; 18(12):1792-8. PubMed ID: 16359169
    [Abstract] [Full Text] [Related]

  • 2. Characterization of multiple products of cytochrome P450 2A6-catalyzed cotinine metabolism.
    Murphy SE, Johnson LM, Pullo DA.
    Chem Res Toxicol; 1999 Jul; 12(7):639-45. PubMed ID: 10409404
    [Abstract] [Full Text] [Related]

  • 3. N-glucuronidation of trans-3'-hydroxycotinine by human liver microsomes.
    Kuehl GE, Murphy SE.
    Chem Res Toxicol; 2003 Dec; 16(12):1502-6. PubMed ID: 14680362
    [Abstract] [Full Text] [Related]

  • 4. Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.
    Yamanaka H, Nakajima M, Katoh M, Kanoh A, Tamura O, Ishibashi H, Yokoi T.
    Drug Metab Dispos; 2005 Jan; 33(1):23-30. PubMed ID: 15470160
    [Abstract] [Full Text] [Related]

  • 5. Nicotine 5'-oxidation and methyl oxidation by P450 2A enzymes.
    Murphy SE, Raulinaitis V, Brown KM.
    Drug Metab Dispos; 2005 Aug; 33(8):1166-73. PubMed ID: 15860657
    [Abstract] [Full Text] [Related]

  • 6. Simultaneous determination of nicotine, cotinine, norcotinine, and trans-3'-hydroxycotinine in human oral fluid using solid phase extraction and gas chromatography-mass spectrometry.
    Kim I, Darwin WD, Huestis MA.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2005 Jan 25; 814(2):233-40. PubMed ID: 15639444
    [Abstract] [Full Text] [Related]

  • 7. Metabolites of nicotine in rat brain after peripheral nicotine administration. Cotinine, nornicotine, and norcotinine.
    Crooks PA, Li M, Dwoskin LP.
    Drug Metab Dispos; 1997 Jan 25; 25(1):47-54. PubMed ID: 9010629
    [Abstract] [Full Text] [Related]

  • 8. Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes.
    Nakajima M, Yamamoto T, Nunoya K, Yokoi T, Nagashima K, Inoue K, Funae Y, Shimada N, Kamataki T, Kuroiwa Y.
    J Pharmacol Exp Ther; 1996 May 25; 277(2):1010-5. PubMed ID: 8627511
    [Abstract] [Full Text] [Related]

  • 9. Determination of the nicotine metabolites cotinine and trans-3'-hydroxycotinine in biologic fluids of smokers and non-smokers using liquid chromatography-tandem mass spectrometry: biomarkers for tobacco smoke exposure and for phenotyping cytochrome P450 2A6 activity.
    Jacob P, Yu L, Duan M, Ramos L, Yturralde O, Benowitz NL.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2011 Feb 01; 879(3-4):267-76. PubMed ID: 21208832
    [Abstract] [Full Text] [Related]

  • 10. Evidence for urinary excretion of glucuronide conjugates of nicotine, cotinine, and trans-3'-hydroxycotinine in smokers.
    Byrd GD, Chang KM, Greene JM, deBethizy JD.
    Drug Metab Dispos; 1992 Feb 01; 20(2):192-7. PubMed ID: 1352209
    [Abstract] [Full Text] [Related]

  • 11. Effects of watercress consumption on urinary metabolites of nicotine in smokers.
    Hecht SS, Carmella SG, Murphy SE.
    Cancer Epidemiol Biomarkers Prev; 1999 Oct 01; 8(10):907-13. PubMed ID: 10548320
    [Abstract] [Full Text] [Related]

  • 12. Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites.
    Avent KM, DeVoss JJ, Gillam EM.
    Chem Res Toxicol; 2006 Jul 01; 19(7):914-20. PubMed ID: 16841959
    [Abstract] [Full Text] [Related]

  • 13. Biotransformation of primary nicotine metabolites. II. Metabolism of [3H]-S-(-)-cotinine in the guinea pig: determination of in vivo urinary metabolites by high-performance liquid-radiochromatography.
    Cundy KC, Crooks PA.
    Xenobiotica; 1987 Jul 01; 17(7):785-92. PubMed ID: 3660848
    [Abstract] [Full Text] [Related]

  • 14. Female sex and oral contraceptive use accelerate nicotine metabolism.
    Benowitz NL, Lessov-Schlaggar CN, Swan GE, Jacob P.
    Clin Pharmacol Ther; 2006 May 01; 79(5):480-8. PubMed ID: 16678549
    [Abstract] [Full Text] [Related]

  • 15. CYP2C19 Plays a Major Role in the Hepatic N-Oxidation of Cotinine.
    Perez-Paramo YX, Watson CJW, Chen G, Lazarus P.
    Drug Metab Dispos; 2023 Jan 01; 51(1):29-37. PubMed ID: 35197312
    [Abstract] [Full Text] [Related]

  • 16. [Concentration of cotinine and trans-3'-hydroxycotinine and its glucuronides in urine of smoking pregnant women].
    Kedziora H, Florek E, Piekoszewski W, Breborowicz GH, Anholcer A, Gomółka E, Kulza M, Stanek A.
    Przegl Lek; 2007 Jan 01; 64(10):740-6. PubMed ID: 18409299
    [Abstract] [Full Text] [Related]

  • 17. Effect of nicotine and nicotine metabolites on angiotensin-converting enzyme in human endothelial cells.
    Ljungberg LU, Persson K.
    Endothelium; 2008 Jan 01; 15(5-6):239-45. PubMed ID: 19065315
    [Abstract] [Full Text] [Related]

  • 18. Pharmacokinetics of nicotine, cotinine, and 3'-hydroxycotinine in cigarette smokers.
    Scherer G, Jarczyk L, Heller WD, Biber A, Neurath GB, Adlkofer F.
    Klin Wochenschr; 1988 Jan 01; 66 Suppl 11():5-11. PubMed ID: 3184779
    [Abstract] [Full Text] [Related]

  • 19. Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-butanone metabolism by cytochrome P450 2B6.
    Dicke KE, Skrlin SM, Murphy SE.
    Drug Metab Dispos; 2005 Dec 01; 33(12):1760-4. PubMed ID: 16174803
    [Abstract] [Full Text] [Related]

  • 20. Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation.
    Lerman C, Tyndale R, Patterson F, Wileyto EP, Shields PG, Pinto A, Benowitz N.
    Clin Pharmacol Ther; 2006 Jun 01; 79(6):600-8. PubMed ID: 16765148
    [Abstract] [Full Text] [Related]


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