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Journal Abstract Search

193 related items for PubMed ID: 16359840

  • 1. In vitro methods in human drug biotransformation research: implications for cancer chemotherapy.
    Hariparsad N, Sane RS, Strom SC, Desai PB.
    Toxicol In Vitro; 2006 Mar; 20(2):135-53. PubMed ID: 16359840
    [Abstract] [Full Text] [Related]

  • 2. Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo.
    Gómez-Lechón MJ, Castell JV, Donato MT.
    Chem Biol Interact; 2007 May 20; 168(1):30-50. PubMed ID: 17134688
    [Abstract] [Full Text] [Related]

  • 3. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
    Kalgutkar AS, Hatch HL, Kosea F, Nguyen HT, Choo EF, McClure KF, Taylor TJ, Henne KR, Kuperman AV, Dombroski MA, Letavic MA.
    Biopharm Drug Dispos; 2006 Nov 20; 27(8):371-86. PubMed ID: 16944451
    [Abstract] [Full Text] [Related]

  • 4. [Development of antituberculous drugs: current status and future prospects].
    Tomioka H, Namba K.
    Kekkaku; 2006 Dec 20; 81(12):753-74. PubMed ID: 17240921
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  • 7. Role of human liver microsomes in in vitro metabolism of drugs-a review.
    Asha S, Vidyavathi M.
    Appl Biochem Biotechnol; 2010 Mar 20; 160(6):1699-722. PubMed ID: 19582595
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  • 8. Assessment of three human in vitro systems in the generation of major human excretory and circulating metabolites.
    Dalvie D, Obach RS, Kang P, Prakash C, Loi CM, Hurst S, Nedderman A, Goulet L, Smith E, Bu HZ, Smith DA.
    Chem Res Toxicol; 2009 Feb 20; 22(2):357-68. PubMed ID: 19146377
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  • 9. Human hepatocytes: isolation, cryopreservation and applications in drug development.
    Li AP.
    Chem Biol Interact; 2007 May 20; 168(1):16-29. PubMed ID: 17270162
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  • 10. Extrapolation of preclinical pharmacokinetic data to therapeutic drug use.
    Rahmani R, Richard B, Fabre G, Cano JP.
    Xenobiotica; 1988 Jan 20; 18 Suppl 1():71-88. PubMed ID: 3344591
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  • 11. [Drug interactions in medical oncology].
    Ishiguro H, Koshiji M, Morizane T, Taniai H, Enatsu S, Fujimoto T, Nambu Y.
    Gan To Kagaku Ryoho; 2009 May 20; 36(5):879-85. PubMed ID: 19461200
    [Abstract] [Full Text] [Related]

  • 12. Lenalidomide: in vitro evaluation of the metabolism and assessment of cytochrome P450 inhibition and induction.
    Kumar G, Lau H, Laskin O.
    Cancer Chemother Pharmacol; 2009 May 20; 63(6):1171-5. PubMed ID: 19030860
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  • 14. [Preclinical data as basis for the design of clinical studies].
    Fichtner I.
    Onkologie; 2008 May 20; 31 Suppl 2():34-8. PubMed ID: 18487867
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  • 15. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
    EFSA GMO Panel Working Group on Animal Feeding Trials.
    Food Chem Toxicol; 2008 Mar 20; 46 Suppl 1():S2-70. PubMed ID: 18328408
    [Abstract] [Full Text] [Related]

  • 16. Pharmacokinetics and metabolism of vinca alkaloids.
    Rahmani R, Zhou XJ.
    Cancer Surv; 1993 Mar 20; 17():269-81. PubMed ID: 8137344
    [Abstract] [Full Text] [Related]

  • 17. Cytochrome P450s in the development of target-based anticancer drugs.
    Purnapatre K, Khattar SK, Saini KS.
    Cancer Lett; 2008 Jan 18; 259(1):1-15. PubMed ID: 18053638
    [Abstract] [Full Text] [Related]

  • 18. [Timeline from discovery of 5-FU to development of an oral anticancer agent S-1 and its drug concept].
    Shirasaka T, Taguchi T.
    Gan To Kagaku Ryoho; 2006 Jun 18; 33 Suppl 1():4-18. PubMed ID: 16897967
    [Abstract] [Full Text] [Related]

  • 19. Predictability of the in vivo metabolism of verapamil from in vitro data: contribution of individual metabolic pathways and stereoselective aspects.
    Kroemer HK, Echizen H, Heidemann H, Eichelbaum M.
    J Pharmacol Exp Ther; 1992 Mar 18; 260(3):1052-7. PubMed ID: 1545377
    [Abstract] [Full Text] [Related]

  • 20. In vitro metabolism of rivaroxaban, an oral, direct factor Xa inhibitor, in liver microsomes and hepatocytes of rats, dogs, and humans.
    Lang D, Freudenberger C, Weinz C.
    Drug Metab Dispos; 2009 May 18; 37(5):1046-55. PubMed ID: 19196846
    [Abstract] [Full Text] [Related]

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