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Journal Abstract Search

228 related items for PubMed ID: 16360707

  • 1. Phenylsulphonyl urenyl chalcone derivatives as dual inhibitors of cyclo-oxygenase-2 and 5-lipoxygenase.
    Araico A, Terencio MC, Alcaraz MJ, Domínguez JN, León C, Ferrándiz ML.
    Life Sci; 2006 May 15; 78(25):2911-8. PubMed ID: 16360707
    [Abstract] [Full Text] [Related]

  • 2. Synthesis of 1,5-diarylpyrazol-3-propanoic acids towards inhibition of cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4 formation.
    Ergün BC, Nuñez MT, Labeaga L, Ledo F, Darlington J, Bain G, Cakir B, Banoglu E.
    Arzneimittelforschung; 2010 May 15; 60(8):497-505. PubMed ID: 20863006
    [Abstract] [Full Text] [Related]

  • 3. Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile.
    Argentieri DC, Ritchie DM, Ferro MP, Kirchner T, Wachter MP, Anderson DW, Rosenthale ME, Capetola RJ.
    J Pharmacol Exp Ther; 1994 Dec 15; 271(3):1399-408. PubMed ID: 7996452
    [Abstract] [Full Text] [Related]

  • 4. Dual inhibition of 5-lipoxygenase/cyclooxygenase by a reconstituted homeopathic remedy; possible explanation for clinical efficacy and favourable gastrointestinal tolerability.
    Jäggi R, Würgler U, Grandjean F, Weiser M.
    Inflamm Res; 2004 Apr 15; 53(4):150-7. PubMed ID: 15060721
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors.
    Cusan C, Spalluto G, Prato M, Adams M, Bodensieck A, Bauer R, Tubaro A, Bernardi P, Da Ros T.
    Farmaco; 2005 Apr 15; 60(4):327-32. PubMed ID: 15848208
    [Abstract] [Full Text] [Related]

  • 6. Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production.
    Chen CS, Tan CM, Huang CH, Chang LC, Wang JP, Cheng FC, Chern JW.
    Bioorg Med Chem; 2010 Jan 15; 18(2):597-604. PubMed ID: 20056549
    [Abstract] [Full Text] [Related]

  • 7. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation.
    Kirchner T, Argentieri DC, Barbone AG, Singer M, Steber M, Ansell J, Beers SA, Wachter MP, Wu W, Malloy E, Stewart A, Ritchie DM.
    J Pharmacol Exp Ther; 1997 Aug 15; 282(2):1094-101. PubMed ID: 9262379
    [Abstract] [Full Text] [Related]

  • 8. Inhibitory effect of Panax notoginseng on nitric oxide synthase, cyclo-oxygenase-2 and neutrophil functions.
    Jin UH, Park SG, Suh SJ, Kim JK, Kim DS, Moon SK, Lee YC, Park WH, Kim CH.
    Phytother Res; 2007 Feb 15; 21(2):142-8. PubMed ID: 17128437
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN, Chen QH, Knaus EE.
    J Med Chem; 2006 Mar 09; 49(5):1668-83. PubMed ID: 16509583
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and anti-inflammatory activity of chalcone derivatives.
    Herencia F, Ferrándiz ML, Ubeda A, Domínguez JN, Charris JE, Lobo GM, Alcaraz MJ.
    Bioorg Med Chem Lett; 1998 May 19; 8(10):1169-74. PubMed ID: 9871729
    [Abstract] [Full Text] [Related]

  • 11. CP-66,248, a new anti-inflammatory agent, is a potent inhibitor of leukotriene B4 and prostanoid synthesis in human polymorphonuclear leucocytes in vitro.
    Moilanen E, Alanko J, Asmawi MZ, Vapaatalo H.
    Eicosanoids; 1988 May 19; 1(1):35-9. PubMed ID: 2856170
    [Abstract] [Full Text] [Related]

  • 12. Evaluation of the anti-inflammatory and analgesic activity of Me-UCH9, a dual cyclooxygenase-2/5-lipoxygenase inhibitor.
    Araico A, Terencio MC, Alcaraz MJ, Domínguez JN, León C, Ferrándiz ML.
    Life Sci; 2007 May 16; 80(23):2108-2117. PubMed ID: 17490689
    [Abstract] [Full Text] [Related]

  • 13. Dibenzoxepinone hydroxylamines and hydroxamic acids: dual inhibitors of cyclooxygenase and 5-lipoxygenase with potent topical antiinflammatory activity.
    Hamer RR, Tegeler JJ, Kurtz ES, Allen RC, Bailey SC, Elliott ME, Hellyer L, Helsley GC, Przekop P, Freed BS, White J, Martin LL.
    J Med Chem; 1996 Jan 05; 39(1):246-52. PubMed ID: 8568814
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of leukocyte eicosanoid generation and radical scavenging activity by gnaphalin, a lipophilic flavonol isolated from Helichrysum picardii.
    de la Puerta R, Forder RA, Hoult JR.
    Planta Med; 1999 Aug 05; 65(6):507-11. PubMed ID: 10483368
    [Abstract] [Full Text] [Related]

  • 15. Computer-aided discovery of anti-inflammatory thiazolidinones with dual cyclooxygenase/lipoxygenase inhibition.
    Geronikaki AA, Lagunin AA, Hadjipavlou-Litina DI, Eleftheriou PT, Filimonov DA, Poroikov VV, Alam I, Saxena AK.
    J Med Chem; 2008 Mar 27; 51(6):1601-9. PubMed ID: 18311898
    [Abstract] [Full Text] [Related]

  • 16. Design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4-formation.
    Schühly W, Hüfner A, Pferschy-Wenzig EM, Prettner E, Adams M, Bodensieck A, Kunert O, Oluwemimo A, Haslinger E, Bauer R.
    Bioorg Med Chem; 2009 Jul 01; 17(13):4459-65. PubMed ID: 19481465
    [Abstract] [Full Text] [Related]

  • 17. The anti-inflammatory effects of ZLJ-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor.
    Li L, Ji H, Sheng L, Zhang Y, Lai Y, Chen X.
    Eur J Pharmacol; 2009 Apr 01; 607(1-3):244-50. PubMed ID: 19243697
    [Abstract] [Full Text] [Related]

  • 18. 5-Lipoxygenase inhibitors: synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones.
    Bhatia PA, Brooks CD, Basha A, Ratajczyk JD, Gunn BP, Bouska JB, Lanni C, Young PR, Bell RL, Carter GW.
    J Med Chem; 1996 Sep 27; 39(20):3938-50. PubMed ID: 8831760
    [Abstract] [Full Text] [Related]

  • 19. Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and whole blood.
    Ahmad S, Israf DA, Lajis NH, Shaari K, Mohamed H, Wahab AA, Ariffin KT, Hoo WY, Aziz NA, Kadir AA, Sulaiman MR, Somchit MN.
    Eur J Pharmacol; 2006 May 24; 538(1-3):188-94. PubMed ID: 16650843
    [Abstract] [Full Text] [Related]

  • 20. Inhibitory effects of Mannich bases of heterocyclic chalcones on NO production by activated RAW 264.7 macrophages and superoxide anion generation and elastase release by activated human neutrophils.
    Reddy MV, Hwang TL, Leu YL, Chiou WF, Wu TS.
    Bioorg Med Chem; 2011 Apr 15; 19(8):2751-6. PubMed ID: 21441032
    [Abstract] [Full Text] [Related]

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