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Journal Abstract Search

200 related items for PubMed ID: 16376076

  • 1. Synthesis of Tic-D-Phe Psi[CH2-CH2] isostere and its use in the development of melanocortin receptor agonists.
    Tian X, Chen X, Gan L, Hayes JC, Switzer AG, Solinsky MG, Ebetino FH, Wos JA, Pinney BB, Farmer JA, Crossdoersen D, Sheldon RJ.
    Bioorg Med Chem Lett; 2006 Mar 15; 16(6):1721-5. PubMed ID: 16376076
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  • 11. A concise synthesis of 1,4-dihydro-[1,4]diazepine-5,7-dione, a novel 7-TM receptor ligand core structure with melanocortin receptor agonist activity.
    Szewczyk JR, Laudeman CP, Sammond DM, Villeneuve M, Minick DJ, Grizzle MK, Daniels AJ, Andrews JL, Ignar DM.
    Bioorg Med Chem; 2010 Mar 01; 18(5):1822-33. PubMed ID: 20172734
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  • 12. N-terminal fatty acylated His-dPhe-Arg-Trp-NH(2) tetrapeptides: influence of fatty acid chain length on potency and selectivity at the mouse melanocortin receptors and human melanocytes.
    Todorovic A, Holder JR, Bauzo RM, Scott JW, Kavanagh R, Abdel-Malek Z, Haskell-Luevano C.
    J Med Chem; 2005 May 05; 48(9):3328-36. PubMed ID: 15857138
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  • 15. A predictive pharmacophore model of human melanocortin-4 receptor as derived from the solution structures of cyclic peptides.
    Sun H, Greeley DN, Chu XJ, Cheung A, Danho W, Swistok J, Wang Y, Zhao C, Chen L, Fry DC.
    Bioorg Med Chem; 2004 May 15; 12(10):2671-7. PubMed ID: 15110848
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  • 18. End-capping of the modified melanocortin tetrapeptide (p-Cl)Phe-D-Phe-Arg-Trp-NH2 as a route to hMC4R agonists.
    Koikov LN, Ebetino FH, Hayes JC, Cross-Doersen D, Knittel JJ.
    Bioorg Med Chem Lett; 2004 Oct 04; 14(19):4839-42. PubMed ID: 15341935
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  • 19. Melanocortin subtype 4 receptor agonists: structure-activity relationships about the 4-alkyl piperidine core.
    Sebhat IK, Lai Y, Barakat K, Ye Z, Tang R, Kalyani RN, Vongs A, Macneil T, Weinberg DH, Cabello MA, Maroto M, Teran A, Fong TM, Van der Ploeg LH, Patchett AA, Nargund RP.
    Bioorg Med Chem Lett; 2007 Oct 15; 17(20):5720-3. PubMed ID: 17768046
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  • 20. Synthesis and SAR of potent and orally bioavailable tert-butylpyrrolidine archetype derived melanocortin subtype-4 receptor modulators.
    Guo L, Ye Z, Ujjainwalla F, Sings HL, Sebhat IK, Huber J, Weinberg DH, Tang R, MacNeil T, Tamvakopoulos C, Peng Q, MacIntyre E, van der Ploeg LH, Goulet MT, Wyvratt MJ, Nargund RP.
    Bioorg Med Chem Lett; 2008 Jun 01; 18(11):3242-7. PubMed ID: 18479920
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