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227 related items for PubMed ID: 16377779

  • 1. Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb.
    Blazek D, Barboric M, Kohoutek J, Oven I, Peterlin BM.
    Nucleic Acids Res; 2005; 33(22):7000-10. PubMed ID: 16377779
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  • 2. A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb.
    Yik JH, Chen R, Pezda AC, Samford CS, Zhou Q.
    Mol Cell Biol; 2004 Jun; 24(12):5094-105. PubMed ID: 15169877
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  • 3. Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor.
    Michels AA, Fraldi A, Li Q, Adamson TE, Bonnet F, Nguyen VT, Sedore SC, Price JP, Price DH, Lania L, Bensaude O.
    EMBO J; 2004 Jul 07; 23(13):2608-19. PubMed ID: 15201869
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  • 4. Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb.
    Barboric M, Kohoutek J, Price JP, Blazek D, Price DH, Peterlin BM.
    EMBO J; 2005 Dec 21; 24(24):4291-303. PubMed ID: 16362050
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  • 5. Regulation of polymerase II transcription by 7SK snRNA: two distinct RNA elements direct P-TEFb and HEXIM1 binding.
    Egloff S, Van Herreweghe E, Kiss T.
    Mol Cell Biol; 2006 Jan 21; 26(2):630-42. PubMed ID: 16382153
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  • 6. Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression.
    Mbonye UR, Wang B, Gokulrangan G, Chance MR, Karn J.
    Proteomics; 2015 Jun 21; 15(12):2078-86. PubMed ID: 25900325
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  • 7. Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186.
    Li Q, Price JP, Byers SA, Cheng D, Peng J, Price DH.
    J Biol Chem; 2005 Aug 05; 280(31):28819-26. PubMed ID: 15965233
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  • 10. Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA.
    Chen R, Yang Z, Zhou Q.
    J Biol Chem; 2004 Feb 06; 279(6):4153-60. PubMed ID: 14627702
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  • 11. Specificity of Hexim1 and Hexim2 complex formation with cyclin T1/T2, importin alpha and 7SK snRNA.
    Czudnochowski N, Vollmuth F, Baumann S, Vogel-Bachmayr K, Geyer M.
    J Mol Biol; 2010 Jan 08; 395(1):28-41. PubMed ID: 19883659
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  • 15. Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator Tat.
    Muniz L, Egloff S, Ughy B, Jády BE, Kiss T.
    PLoS Pathog; 2010 Oct 14; 6(10):e1001152. PubMed ID: 20976203
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  • 16. Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR.
    Sedore SC, Byers SA, Biglione S, Price JP, Maury WJ, Price DH.
    Nucleic Acids Res; 2007 Oct 14; 35(13):4347-58. PubMed ID: 17576689
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