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Journal Abstract Search

176 related items for PubMed ID: 16378095

  • 1. A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference.
    Samakoglu S, Lisowski L, Budak-Alpdogan T, Usachenko Y, Acuto S, Di Marzo R, Maggio A, Zhu P, Tisdale JF, Rivière I, Sadelain M.
    Nat Biotechnol; 2006 Jan; 24(1):89-94. PubMed ID: 16378095
    [Abstract] [Full Text] [Related]

  • 2. Recent advances in globin gene transfer for the treatment of beta-thalassemia and sickle cell anemia.
    Sadelain M.
    Curr Opin Hematol; 2006 May; 13(3):142-8. PubMed ID: 16567956
    [Abstract] [Full Text] [Related]

  • 3. Globin gene transfer for treatment of the beta-thalassemias and sickle cell disease.
    Sadelain M, Rivella S, Lisowski L, Samakoglu S, Rivière I.
    Best Pract Res Clin Haematol; 2004 Sep; 17(3):517-34. PubMed ID: 15498721
    [Abstract] [Full Text] [Related]

  • 4. Expression of an anti-sickling beta-globin in human erythroblasts derived from retrovirally transduced primitive normal and sickle cell disease hematopoietic cells.
    Oh IH, Fabry ME, Humphries RK, Pawliuk R, Leboulch P, Hoffman R, Nagel RL, Eaves C.
    Exp Hematol; 2004 May; 32(5):461-9. PubMed ID: 15145214
    [Abstract] [Full Text] [Related]

  • 5. Targeted beta-globin gene conversion in human hematopoietic CD34(+ )and Lin(-)CD38(-)cells.
    Liu H, Agarwal S, Kmiec E, Davis BR.
    Gene Ther; 2002 Jan; 9(2):118-26. PubMed ID: 11857070
    [Abstract] [Full Text] [Related]

  • 6. Genetic treatment of severe hemoglobinopathies: the combat against transgene variegation and transgene silencing.
    Rivella S, Sadelain M.
    Semin Hematol; 1998 Apr; 35(2):112-25. PubMed ID: 9565154
    [Abstract] [Full Text] [Related]

  • 7. Progress toward the genetic treatment of the beta-thalassemias.
    Sadelain M, Lisowski L, Samakoglu S, Rivella S, May C, Riviere I.
    Ann N Y Acad Sci; 2005 Apr; 1054():78-91. PubMed ID: 16339654
    [Abstract] [Full Text] [Related]

  • 8. Correction of sickle cell disease in transgenic mouse models by gene therapy.
    Pawliuk R, Westerman KA, Fabry ME, Payen E, Tighe R, Bouhassira EE, Acharya SA, Ellis J, London IM, Eaves CJ, Humphries RK, Beuzard Y, Nagel RL, Leboulch P.
    Science; 2001 Dec 14; 294(5550):2368-71. PubMed ID: 11743206
    [Abstract] [Full Text] [Related]

  • 9. Anti-beta s-ribozyme reduces beta s mRNA levels in transgenic mice: potential application to the gene therapy of sickle cell anemia.
    Alami R, Gilman JG, Feng YQ, Marmorato A, Rochlin I, Suzuka SM, Fabry ME, Nagel RL, Bouhassira EE.
    Blood Cells Mol Dis; 1999 Apr 14; 25(2):110-9. PubMed ID: 10389593
    [Abstract] [Full Text] [Related]

  • 10. Current status of globin gene therapy for the treatment of beta-thalassaemia.
    Lisowski L, Sadelain M.
    Br J Haematol; 2008 May 14; 141(3):335-45. PubMed ID: 18410569
    [Abstract] [Full Text] [Related]

  • 11. Gene therapy for the hemoglobin disorders.
    Persons DA, Nienhuis AW.
    Curr Hematol Rep; 2003 Jul 14; 2(4):348-55. PubMed ID: 12901333
    [Abstract] [Full Text] [Related]

  • 12. Beta globin gene inhibition by antisense RNA transcripts.
    Xu L, Ferry AE, Monteiro C, Pace BS.
    Gene Ther; 2000 Mar 14; 7(5):438-44. PubMed ID: 10694826
    [Abstract] [Full Text] [Related]

  • 13. Gene therapy. Gene gemisch cures sickle cell in mice.
    Marshall E.
    Science; 2001 Dec 14; 294(5550):2268. PubMed ID: 11743172
    [No Abstract] [Full Text] [Related]

  • 14. Gene therapy for hemoglobinopathies: are we there yet?
    Puthenveetil G, Malik P.
    Curr Hematol Rep; 2004 Jul 14; 3(4):298-305. PubMed ID: 15217560
    [Abstract] [Full Text] [Related]

  • 15. Nonviral vector-mediated RNA interference: its gene silencing characteristics and important factors to achieve RNAi-based gene therapy.
    Takahashi Y, Nishikawa M, Takakura Y.
    Adv Drug Deliv Rev; 2009 Jul 25; 61(9):760-6. PubMed ID: 19386274
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of alpha-globin gene expression by RNAi.
    Sarakul O, Vattanaviboon P, Wilairat P, Fucharoen S, Abe Y, Muta K.
    Biochem Biophys Res Commun; 2008 May 09; 369(3):935-8. PubMed ID: 18328259
    [Abstract] [Full Text] [Related]

  • 17. Restoration of the balanced alpha/beta-globin gene expression in beta654-thalassemia mice using combined RNAi and antisense RNA approach.
    Xie SY, Ren ZR, Zhang JZ, Guo XB, Wang QX, Wang S, Lin D, Gong XL, Li W, Huang SZ, Zeng F, Zeng YT.
    Hum Mol Genet; 2007 Nov 01; 16(21):2616-25. PubMed ID: 17716993
    [Abstract] [Full Text] [Related]

  • 18. Application of SFHR to gene therapy of monogenic disorders.
    Goncz KK, Prokopishyn NL, Chow BL, Davis BR, Gruenert DC.
    Gene Ther; 2002 Jun 01; 9(11):691-4. PubMed ID: 12032689
    [Abstract] [Full Text] [Related]

  • 19. Modulation of gene expression by siRNA in hematopoietic cells.
    Scherr M, Eder M.
    Curr Opin Drug Discov Devel; 2005 Mar 01; 8(2):262-9. PubMed ID: 15782549
    [Abstract] [Full Text] [Related]

  • 20. The gamma-globin gene promoter progressively demethylates as the hematopoietic stem progenitor cells differentiate along the erythroid lineage in baboon fetal liver and adult bone marrow.
    Singh M, Lavelle D, Vaitkus K, Mahmud N, Hankewych M, DeSimone J.
    Exp Hematol; 2007 Jan 01; 35(1):48-55. PubMed ID: 17198873
    [Abstract] [Full Text] [Related]

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