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Journal Abstract Search

231 related items for PubMed ID: 16380384

  • 1. Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione.
    Bai J, Cederbaum AI.
    J Biol Chem; 2006 Feb 24; 281(8):5128-36. PubMed ID: 16380384
    [Abstract] [Full Text] [Related]

  • 2. Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1.
    Marí M, Bai J, Cederbaum AI.
    J Pharmacol Exp Ther; 2002 Apr 24; 301(1):111-8. PubMed ID: 11907164
    [Abstract] [Full Text] [Related]

  • 3. Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1.
    Wu D, Cederbaum AI.
    Alcohol Clin Exp Res; 2001 Apr 24; 25(4):619-28. PubMed ID: 11329505
    [Abstract] [Full Text] [Related]

  • 4. Mitochondria-targeted cytochrome P450 2E1 induces oxidative damage and augments alcohol-mediated oxidative stress.
    Bansal S, Liu CP, Sepuri NB, Anandatheerthavarada HK, Selvaraj V, Hoek J, Milne GL, Guengerich FP, Avadhani NG.
    J Biol Chem; 2010 Aug 06; 285(32):24609-19. PubMed ID: 20529841
    [Abstract] [Full Text] [Related]

  • 5. Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells.
    Pérez MJ, Cederbaum AI.
    Hepatology; 2003 Jun 06; 37(6):1395-404. PubMed ID: 12774019
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK.
    Wu D, Cederbaum AI.
    Redox Biol; 2013 Jun 06; 1(1):552-65. PubMed ID: 24273738
    [Abstract] [Full Text] [Related]

  • 7. Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1.
    Zhuge J, Cederbaum AI.
    Free Radic Biol Med; 2006 Jan 01; 40(1):63-74. PubMed ID: 16337880
    [Abstract] [Full Text] [Related]

  • 8. Differential role of ethanol and acetaldehyde in the induction of oxidative stress in HEP G2 cells: effect on transcription factors AP-1 and NF-kappaB.
    Román J, Colell A, Blasco C, Caballeria J, Parés A, Rodés J, Fernández-Checa JC.
    Hepatology; 1999 Dec 01; 30(6):1473-80. PubMed ID: 10573527
    [Abstract] [Full Text] [Related]

  • 9. Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes.
    Bansal S, Srinivasan S, Anandasadagopan S, Chowdhury AR, Selvaraj V, Kalyanaraman B, Joseph J, Avadhani NG.
    J Biol Chem; 2012 May 04; 287(19):15284-97. PubMed ID: 22396533
    [Abstract] [Full Text] [Related]

  • 10. Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo.
    Wang X, Wu D, Yang L, Gan L, Cederbaum AI.
    Free Radic Biol Med; 2013 Oct 04; 63():175-86. PubMed ID: 23669278
    [Abstract] [Full Text] [Related]

  • 11. Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat hepatocytes.
    Robin MA, Sauvage I, Grandperret T, Descatoire V, Pessayre D, Fromenty B.
    FEBS Lett; 2005 Dec 19; 579(30):6895-902. PubMed ID: 16337197
    [Abstract] [Full Text] [Related]

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  • 13. Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity.
    Pérez MJ, Cederbaum AI.
    Hepatology; 2003 Nov 19; 38(5):1146-58. PubMed ID: 14578853
    [Abstract] [Full Text] [Related]

  • 14. Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity.
    Wu D, Cederbaum A.
    Toxicol Appl Pharmacol; 2006 Oct 15; 216(2):282-92. PubMed ID: 16938321
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  • 16. Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity.
    Wu D, Cederbaum A.
    Mol Pharmacol; 2004 Sep 15; 66(3):749-60. PubMed ID: 15322268
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  • 19. Nrf2 and antioxidant defense against CYP2E1 toxicity.
    Cederbaum A.
    Expert Opin Drug Metab Toxicol; 2009 Oct 15; 5(10):1223-44. PubMed ID: 19671018
    [Abstract] [Full Text] [Related]

  • 20. Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway.
    Gong P, Cederbaum AI, Nieto N.
    J Biol Chem; 2003 Aug 08; 278(32):29693-700. PubMed ID: 12777398
    [Abstract] [Full Text] [Related]

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