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Journal Abstract Search


137 related items for PubMed ID: 16384676

  • 21. Minor compensatory changes in SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats do not detract from their utility in the study of transporter-mediated pharmacokinetics.
    Zamek-Gliszczynski MJ, Goldstein KM, Paulman A, Baker TK, Ryan TP.
    Drug Metab Dispos; 2013 Jun; 41(6):1174-8. PubMed ID: 23569176
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  • 22. Decrease in oral bioavailability of ciclosporin by intravenous pulse of methylprednisolone succinate in rats.
    Konishi H, Sumi M, Shibata N, Takada K, Minouchi T, Yamaji A.
    J Pharm Pharmacol; 2004 Oct; 56(10):1259-66. PubMed ID: 15482640
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  • 23. P-glycoprotein, CYP3A, and plasma carboxylesterase determine brain and blood disposition of the mTOR Inhibitor everolimus (Afinitor) in mice.
    Tang SC, Sparidans RW, Cheung KL, Fukami T, Durmus S, Wagenaar E, Yokoi T, van Vlijmen BJ, Beijnen JH, Schinkel AH.
    Clin Cancer Res; 2014 Jun 15; 20(12):3133-45. PubMed ID: 24727322
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  • 24. Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine.
    Lown KS, Mayo RR, Leichtman AB, Hsiao HL, Turgeon DK, Schmiedlin-Ren P, Brown MB, Guo W, Rossi SJ, Benet LZ, Watkins PB.
    Clin Pharmacol Ther; 1997 Sep 15; 62(3):248-60. PubMed ID: 9333100
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  • 25. Comparison of pharmacokinetics of cyclosporine A in cadaveric and living-related renal transplant recipients and in an experimental rat model of renal failure.
    Sugioka N, Fujimoto K, Tanaka Y, Fukushima K, Ito Y, Kokuhu T, Okamoto M, Yoshimura N, Takada K.
    Drug Metab Lett; 2009 Aug 15; 3(3):152-61. PubMed ID: 19702545
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  • 26. What kinds of substrates show P-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine.
    Ogihara T, Kamiya M, Ozawa M, Fujita T, Yamamoto A, Yamashita S, Ohnishi S, Isomura Y.
    Drug Metab Pharmacokinet; 2006 Jun 15; 21(3):238-44. PubMed ID: 16858128
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  • 27. Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy.
    Shimada T, Terada A, Yokogawa K, Kaneko H, Nomura M, Kaji K, Kaneko S, Kobayashi K, Miyamoto K.
    Transplantation; 2002 Nov 27; 74(10):1419-24. PubMed ID: 12451243
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  • 28. Expression profiles of drug-metabolizing enzyme CYP3A and drug efflux transporter multidrug resistance 1 subfamily mRNAS in small intestine.
    Takara K, Ohnishi N, Horibe S, Yokoyama T.
    Drug Metab Dispos; 2003 Oct 27; 31(10):1235-9. PubMed ID: 12975332
    [Abstract] [Full Text] [Related]

  • 29. Dextran sulfate sodium-induced colitis and ginseng intervention altered oral pharmacokinetics of cyclosporine A in rats.
    Yang Y, Hu N, Gao XJ, Li T, Yan ZX, Wang PP, Wei B, Li S, Zhang ZJ, Li SL, Yan R.
    J Ethnopharmacol; 2021 Jan 30; 265():113251. PubMed ID: 32810615
    [Abstract] [Full Text] [Related]

  • 30. Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.
    Vlaming ML, Teunissen SF, van de Steeg E, van Esch A, Wagenaar E, Brunsveld L, de Greef TF, Rosing H, Schellens JH, Beijnen JH, Schinkel AH.
    Mol Pharmacol; 2014 Mar 30; 85(3):520-30. PubMed ID: 24334255
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  • 31. Sequence-specific suppression of mdr1a/1b expression in mice via RNA interference.
    Matsui Y, Kobayashi N, Nishikawa M, Takakura Y.
    Pharm Res; 2005 Dec 30; 22(12):2091-8. PubMed ID: 16184445
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  • 32. The effect of breast cancer resistance protein and P-glycoprotein on the brain penetration of flavopiridol, imatinib mesylate (Gleevec), prazosin, and 2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid (PF-407288) in mice.
    Zhou L, Schmidt K, Nelson FR, Zelesky V, Troutman MD, Feng B.
    Drug Metab Dispos; 2009 May 30; 37(5):946-55. PubMed ID: 19225039
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  • 33. Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: in vitro-in vivo correlation.
    Fricker G, Drewe J, Huwyler J, Gutmann H, Beglinger C.
    Br J Pharmacol; 1996 Aug 30; 118(7):1841-7. PubMed ID: 8842452
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  • 34. Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption.
    Uhr M, Steckler T, Yassouridis A, Holsboer F.
    Neuropsychopharmacology; 2000 Apr 30; 22(4):380-7. PubMed ID: 10700657
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  • 35. Effect of Pregnenolone 16α-Carbonitrile on the Expression of P-Glycoprotein in the Intestine, Brain and Liver of Mice.
    Yamasaki Y, Kobayashi K, Chiba K.
    Biol Pharm Bull; 2018 Apr 30; 41(6):972-977. PubMed ID: 29863087
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  • 36. Impact of genetic deficiencies of P-glycoprotein and breast cancer resistance protein on pharmacokinetics of aripiprazole and dehydroaripiprazole.
    Nagasaka Y, Sano T, Oda K, Kawamura A, Usui T.
    Xenobiotica; 2014 Oct 30; 44(10):926-32. PubMed ID: 24666334
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  • 37. Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients.
    Yamagata T, Kusuhara H, Morishita M, Takayama K, Benameur H, Sugiyama Y.
    Drug Metab Dispos; 2007 Jul 30; 35(7):1142-8. PubMed ID: 17446265
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  • 38. Estimating Efflux Transporter-Mediated Disposition of Molecules beyond the Rule of Five (bRo5) Using Transporter Gene Knockout Rats.
    Miyake T.
    Biol Pharm Bull; 2020 Mar 01; 43(3):384-392. PubMed ID: 31685755
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  • 39. ATP binding cassette transporters in two distinct compartments of the skin contribute to transdermal absorption of a typical substrate.
    Hashimoto N, Nakamichi N, Uwafuji S, Yoshida K, Sugiura T, Tsuji A, Kato Y.
    J Control Release; 2013 Jan 10; 165(1):54-61. PubMed ID: 23089896
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  • 40. Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice.
    Uchida Y, Ohtsuki S, Kamiie J, Terasaki T.
    J Pharmacol Exp Ther; 2011 Nov 10; 339(2):579-88. PubMed ID: 21828264
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