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137 related items for PubMed ID: 16384676
21. Minor compensatory changes in SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats do not detract from their utility in the study of transporter-mediated pharmacokinetics. Zamek-Gliszczynski MJ, Goldstein KM, Paulman A, Baker TK, Ryan TP. Drug Metab Dispos; 2013 Jun; 41(6):1174-8. PubMed ID: 23569176 [Abstract] [Full Text] [Related]
22. Decrease in oral bioavailability of ciclosporin by intravenous pulse of methylprednisolone succinate in rats. Konishi H, Sumi M, Shibata N, Takada K, Minouchi T, Yamaji A. J Pharm Pharmacol; 2004 Oct; 56(10):1259-66. PubMed ID: 15482640 [Abstract] [Full Text] [Related]
23. P-glycoprotein, CYP3A, and plasma carboxylesterase determine brain and blood disposition of the mTOR Inhibitor everolimus (Afinitor) in mice. Tang SC, Sparidans RW, Cheung KL, Fukami T, Durmus S, Wagenaar E, Yokoi T, van Vlijmen BJ, Beijnen JH, Schinkel AH. Clin Cancer Res; 2014 Jun 15; 20(12):3133-45. PubMed ID: 24727322 [Abstract] [Full Text] [Related]
24. Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine. Lown KS, Mayo RR, Leichtman AB, Hsiao HL, Turgeon DK, Schmiedlin-Ren P, Brown MB, Guo W, Rossi SJ, Benet LZ, Watkins PB. Clin Pharmacol Ther; 1997 Sep 15; 62(3):248-60. PubMed ID: 9333100 [Abstract] [Full Text] [Related]
25. Comparison of pharmacokinetics of cyclosporine A in cadaveric and living-related renal transplant recipients and in an experimental rat model of renal failure. Sugioka N, Fujimoto K, Tanaka Y, Fukushima K, Ito Y, Kokuhu T, Okamoto M, Yoshimura N, Takada K. Drug Metab Lett; 2009 Aug 15; 3(3):152-61. PubMed ID: 19702545 [Abstract] [Full Text] [Related]
26. What kinds of substrates show P-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine. Ogihara T, Kamiya M, Ozawa M, Fujita T, Yamamoto A, Yamashita S, Ohnishi S, Isomura Y. Drug Metab Pharmacokinet; 2006 Jun 15; 21(3):238-44. PubMed ID: 16858128 [Abstract] [Full Text] [Related]
27. Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy. Shimada T, Terada A, Yokogawa K, Kaneko H, Nomura M, Kaji K, Kaneko S, Kobayashi K, Miyamoto K. Transplantation; 2002 Nov 27; 74(10):1419-24. PubMed ID: 12451243 [Abstract] [Full Text] [Related]
28. Expression profiles of drug-metabolizing enzyme CYP3A and drug efflux transporter multidrug resistance 1 subfamily mRNAS in small intestine. Takara K, Ohnishi N, Horibe S, Yokoyama T. Drug Metab Dispos; 2003 Oct 27; 31(10):1235-9. PubMed ID: 12975332 [Abstract] [Full Text] [Related]
29. Dextran sulfate sodium-induced colitis and ginseng intervention altered oral pharmacokinetics of cyclosporine A in rats. Yang Y, Hu N, Gao XJ, Li T, Yan ZX, Wang PP, Wei B, Li S, Zhang ZJ, Li SL, Yan R. J Ethnopharmacol; 2021 Jan 30; 265():113251. PubMed ID: 32810615 [Abstract] [Full Text] [Related]
30. Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites. Vlaming ML, Teunissen SF, van de Steeg E, van Esch A, Wagenaar E, Brunsveld L, de Greef TF, Rosing H, Schellens JH, Beijnen JH, Schinkel AH. Mol Pharmacol; 2014 Mar 30; 85(3):520-30. PubMed ID: 24334255 [Abstract] [Full Text] [Related]
31. Sequence-specific suppression of mdr1a/1b expression in mice via RNA interference. Matsui Y, Kobayashi N, Nishikawa M, Takakura Y. Pharm Res; 2005 Dec 30; 22(12):2091-8. PubMed ID: 16184445 [Abstract] [Full Text] [Related]
32. The effect of breast cancer resistance protein and P-glycoprotein on the brain penetration of flavopiridol, imatinib mesylate (Gleevec), prazosin, and 2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid (PF-407288) in mice. Zhou L, Schmidt K, Nelson FR, Zelesky V, Troutman MD, Feng B. Drug Metab Dispos; 2009 May 30; 37(5):946-55. PubMed ID: 19225039 [Abstract] [Full Text] [Related]
33. Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: in vitro-in vivo correlation. Fricker G, Drewe J, Huwyler J, Gutmann H, Beglinger C. Br J Pharmacol; 1996 Aug 30; 118(7):1841-7. PubMed ID: 8842452 [Abstract] [Full Text] [Related]
34. Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption. Uhr M, Steckler T, Yassouridis A, Holsboer F. Neuropsychopharmacology; 2000 Apr 30; 22(4):380-7. PubMed ID: 10700657 [Abstract] [Full Text] [Related]
35. Effect of Pregnenolone 16α-Carbonitrile on the Expression of P-Glycoprotein in the Intestine, Brain and Liver of Mice. Yamasaki Y, Kobayashi K, Chiba K. Biol Pharm Bull; 2018 Apr 30; 41(6):972-977. PubMed ID: 29863087 [Abstract] [Full Text] [Related]
36. Impact of genetic deficiencies of P-glycoprotein and breast cancer resistance protein on pharmacokinetics of aripiprazole and dehydroaripiprazole. Nagasaka Y, Sano T, Oda K, Kawamura A, Usui T. Xenobiotica; 2014 Oct 30; 44(10):926-32. PubMed ID: 24666334 [Abstract] [Full Text] [Related]
37. Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients. Yamagata T, Kusuhara H, Morishita M, Takayama K, Benameur H, Sugiyama Y. Drug Metab Dispos; 2007 Jul 30; 35(7):1142-8. PubMed ID: 17446265 [Abstract] [Full Text] [Related]
38. Estimating Efflux Transporter-Mediated Disposition of Molecules beyond the Rule of Five (bRo5) Using Transporter Gene Knockout Rats. Miyake T. Biol Pharm Bull; 2020 Mar 01; 43(3):384-392. PubMed ID: 31685755 [Abstract] [Full Text] [Related]
39. ATP binding cassette transporters in two distinct compartments of the skin contribute to transdermal absorption of a typical substrate. Hashimoto N, Nakamichi N, Uwafuji S, Yoshida K, Sugiura T, Tsuji A, Kato Y. J Control Release; 2013 Jan 10; 165(1):54-61. PubMed ID: 23089896 [Abstract] [Full Text] [Related]
40. Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice. Uchida Y, Ohtsuki S, Kamiie J, Terasaki T. J Pharmacol Exp Ther; 2011 Nov 10; 339(2):579-88. PubMed ID: 21828264 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]