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765 related items for PubMed ID: 1638680

  • 1. Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice.
    Csanády GA, Guengerich FP, Bond JA.
    Carcinogenesis; 1992 Jul; 13(7):1143-53. PubMed ID: 1638680
    [Abstract] [Full Text] [Related]

  • 2. Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes.
    Seaton MJ, Follansbee MH, Bond JA.
    Carcinogenesis; 1995 Oct; 16(10):2287-93. PubMed ID: 7586124
    [Abstract] [Full Text] [Related]

  • 3. Glutathione conjugation of 1,2:3,4- diepoxybutane in human liver and rat and mouse liver and lung in vitro.
    Boogaard PJ, Sumner SC, Bond JA.
    Toxicol Appl Pharmacol; 1996 Feb; 136(2):307-16. PubMed ID: 8619238
    [Abstract] [Full Text] [Related]

  • 4. Research strategy for assessing target tissue dosimetry of 1,3-butadiene in laboratory animals and humans.
    Bond JA, Csanády GA, Leavens T, Medinsky MA.
    IARC Sci Publ; 1993 Feb; (127):45-55. PubMed ID: 8070886
    [Abstract] [Full Text] [Related]

  • 5. Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation.
    Himmelstein MW, Turner MJ, Asgharian B, Bond JA.
    Carcinogenesis; 1994 Aug; 15(8):1479-86. PubMed ID: 8055623
    [Abstract] [Full Text] [Related]

  • 6. Stereochemical aspects of 1,3-butadiene metabolism and toxicity in rat and mouse liver microsomes and freshly isolated rat hepatocytes.
    Nieusma JL, Claffey DJ, Maniglier-Poulet C, Imiolczyk T, Ross D, Ruth JA.
    Chem Res Toxicol; 1997 Apr; 10(4):450-6. PubMed ID: 9114983
    [Abstract] [Full Text] [Related]

  • 7. Species and tissue differences in the microsomal oxidation of 1,3-butadiene and the glutathione conjugation of butadiene monoxide in mice and rats. Possible role in 1,3-butadiene-induced toxicity.
    Sharer JE, Duescher RJ, Elfarra AA.
    Drug Metab Dispos; 1992 Apr; 20(5):658-64. PubMed ID: 1358569
    [Abstract] [Full Text] [Related]

  • 8. In vivo metabolism of butadiene by mice and rats: a comparison of physiological model predictions and experimental data.
    Medinsky MA, Leavens TL, Csanády GA, Gargas ML, Bond JA.
    Carcinogenesis; 1994 Jul; 15(7):1329-40. PubMed ID: 8033308
    [Abstract] [Full Text] [Related]

  • 9. High concentrations of butadiene epoxides in livers and lungs of mice compared to rats exposed to 1,3-butadiene.
    Himmelstein MW, Asgharian B, Bond JA.
    Toxicol Appl Pharmacol; 1995 Jun; 132(2):281-8. PubMed ID: 7785055
    [Abstract] [Full Text] [Related]

  • 10. In vitro metabolism of 4-vinylcyclohexene in rat and mouse liver, lung, and ovary.
    Keller DA, Carpenter SC, Cagen SZ, Reitman FA.
    Toxicol Appl Pharmacol; 1997 May; 144(1):36-44. PubMed ID: 9169067
    [Abstract] [Full Text] [Related]

  • 11. A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation.
    Johanson G, Filser JG.
    Arch Toxicol; 1993 May; 67(3):151-63. PubMed ID: 8494494
    [Abstract] [Full Text] [Related]

  • 12. Kinetic modeling of beta-chloroprene metabolism: I. In vitro rates in liver and lung tissue fractions from mice, rats, hamsters, and humans.
    Himmelstein MW, Carpenter SC, Hinderliter PM.
    Toxicol Sci; 2004 May; 79(1):18-27. PubMed ID: 14976339
    [Abstract] [Full Text] [Related]

  • 13. Determination of mutagenicity in tissues of transgenic mice following exposure to 1,3-butadiene and N-ethyl-N-nitrosourea.
    Recio L, Osterman-Golkar S, Csanády GA, Turner MJ, Myhr B, Moss O, Bond JA.
    Toxicol Appl Pharmacol; 1992 Nov; 117(1):58-64. PubMed ID: 1440614
    [Abstract] [Full Text] [Related]

  • 14. In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach.
    Motwani HV, Törnqvist M.
    Toxicol Appl Pharmacol; 2014 Dec 15; 281(3):276-84. PubMed ID: 25448046
    [Abstract] [Full Text] [Related]

  • 15. Hepatic and pulmonary glutathione conjugation of 1,2:3,4-diepoxybutane in human, rat, and mouse in vitro.
    Boogaard PJ, Sumner SC, Turner MJ, Bond JA.
    Toxicology; 1996 Oct 28; 113(1-3):297-9. PubMed ID: 8901912
    [Abstract] [Full Text] [Related]

  • 16. Disposition of butadiene monoepoxide and butadiene diepoxide in various tissues of rats and mice following a low-level inhalation exposure to 1,3-butadiene.
    Thornton-Manning JR, Dahl AR, Bechtold WE, Griffith WC, Henderson RF.
    Carcinogenesis; 1995 Aug 28; 16(8):1723-31. PubMed ID: 7634396
    [Abstract] [Full Text] [Related]

  • 17. Stereochemical aspects of the conjugation of epoxide metabolites of butadiene with glutathione in rat liver cytosol and freshly isolated rat hepatocytes.
    Nieusma JL, Claffey DJ, Ruth JA, Ross D.
    Toxicol Sci; 1998 Jun 28; 43(2):102-9. PubMed ID: 9710951
    [Abstract] [Full Text] [Related]

  • 18. Oxidation of 1,3-butadiene to (R)- and (S)-butadiene monoxide by purified recombinant cytochrome P450 2E1 from rabbit, rat and human.
    Nieusma JL, Claffey DJ, Koop DR, Chen W, Peter RM, Nelson SD, Ruth JA, Ross D.
    Toxicol Lett; 1998 Mar 31; 95(2):123-9. PubMed ID: 9635416
    [Abstract] [Full Text] [Related]

  • 19. Metabolism of 1,3-butadiene to butadiene monoxide in mouse and human bone marrow cells.
    Maniglier-Poulet C, Cheng X, Ruth JA, Ross D.
    Chem Biol Interact; 1995 Jul 14; 97(2):119-29. PubMed ID: 7606811
    [Abstract] [Full Text] [Related]

  • 20. Cellular and molecular basis for species, sex and tissue differences in 1,3-butadiene metabolism.
    Elfarra AA, Krause RJ, Kemper RA.
    Chem Biol Interact; 2001 Jun 01; 135-136():239-48. PubMed ID: 11397394
    [Abstract] [Full Text] [Related]


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