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343 related items for PubMed ID: 16388594
1. Mutations at leucine 215 of beta-tubulin affect paclitaxel sensitivity by two distinct mechanisms. Wang Y, Yin S, Blade K, Cooper G, Menick DR, Cabral F. Biochemistry; 2006 Jan 10; 45(1):185-94. PubMed ID: 16388594 [Abstract] [Full Text] [Related]
2. Intra-allelic suppression of a mutation that stabilizes microtubules and confers resistance to colcemid. Wang Y, Veeraraghavan S, Cabral F. Biochemistry; 2004 Jul 20; 43(28):8965-73. PubMed ID: 15248754 [Abstract] [Full Text] [Related]
3. Amino acid substitutions at proline 220 of beta-tubulin confer resistance to paclitaxel and colcemid. Yin S, Cabral F, Veeraraghavan S. Mol Cancer Ther; 2007 Oct 20; 6(10):2798-806. PubMed ID: 17938271 [Abstract] [Full Text] [Related]
4. Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel. Hari M, Yang H, Zeng C, Canizales M, Cabral F. Cell Motil Cytoskeleton; 2003 Sep 20; 56(1):45-56. PubMed ID: 12905530 [Abstract] [Full Text] [Related]
5. Paclitaxel selects for mutant or pseudo-null p53 in drug resistance associated with tubulin mutations in human cancer. Giannakakou P, Poy G, Zhan Z, Knutsen T, Blagosklonny MV, Fojo T. Oncogene; 2000 Jun 22; 19(27):3078-85. PubMed ID: 10871860 [Abstract] [Full Text] [Related]
6. Overexpression of an epitope-tagged beta-tubulin in Chinese hamster ovary cells causes an increase in endogenous alpha-tubulin synthesis. Gonzalez-Garay ML, Cabral F. Cell Motil Cytoskeleton; 1995 Jun 22; 31(4):259-72. PubMed ID: 7553913 [Abstract] [Full Text] [Related]
14. Tumor cells resistant to a microtubule-depolymerizing hemiasterlin analogue, HTI-286, have mutations in alpha- or beta-tubulin and increased microtubule stability. Poruchynsky MS, Kim JH, Nogales E, Annable T, Loganzo F, Greenberger LM, Sackett DL, Fojo T. Biochemistry; 2004 Nov 09; 43(44):13944-54. PubMed ID: 15518543 [Abstract] [Full Text] [Related]
15. Expression of beta-tubulin isotypes in human ovarian carcinoma xenografts and in a sub-panel of human cancer cell lines from the NCI-Anticancer Drug Screen: correlation with sensitivity to microtubule active agents. Nicoletti MI, Valoti G, Giannakakou P, Zhan Z, Kim JH, Lucchini V, Landoni F, Mayo JG, Giavazzi R, Fojo T. Clin Cancer Res; 2001 Sep 09; 7(9):2912-22. PubMed ID: 11555610 [Abstract] [Full Text] [Related]
16. Heightened sensitivity to paclitaxel in Class IVa beta-tubulin-transfected cells is lost as expression increases. Yang H, Cabral F. J Biol Chem; 2007 Sep 14; 282(37):27058-27066. PubMed ID: 17627938 [Abstract] [Full Text] [Related]
17. Suppression of microtubule dynamics by epothilone B is associated with mitotic arrest. Kamath K, Jordan MA. Cancer Res; 2003 Sep 15; 63(18):6026-31. PubMed ID: 14522931 [Abstract] [Full Text] [Related]
19. Paclitaxel resistance in cells with reduced beta-tubulin. Wang Y, Cabral F. Biochim Biophys Acta; 2005 Jun 30; 1744(2):245-55. PubMed ID: 15950754 [Abstract] [Full Text] [Related]
20. Human mutations that confer paclitaxel resistance. Yin S, Bhattacharya R, Cabral F. Mol Cancer Ther; 2010 Feb 30; 9(2):327-35. PubMed ID: 20103599 [Abstract] [Full Text] [Related] Page: [Next] [New Search]