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343 related items for PubMed ID: 16388594

  • 21. βI-tubulin mutations in the laulimalide/peloruside binding site mediate drug sensitivity by altering drug-tubulin interactions and microtubule stability.
    Kanakkanthara A, Rowe MR, Field JJ, Northcote PT, Teesdale-Spittle PH, Miller JH.
    Cancer Lett; 2015 Sep 01; 365(2):251-60. PubMed ID: 26052091
    [Abstract] [Full Text] [Related]

  • 22. Differential assembly kinetics of alpha-tubulin isoforms in the presence of paclitaxel.
    Banerjee A, Kasmala LT.
    Biochem Biophys Res Commun; 1998 Apr 17; 245(2):349-51. PubMed ID: 9571153
    [Abstract] [Full Text] [Related]

  • 23. Differential regulation of the cytotoxicity activity of paclitaxel by orobol and platelet derived growth factor in human ovarian carcinoma cells.
    Isonishi S, Saitou M, Saitou M, Yasuda M, Tanaka T.
    Oncol Rep; 2007 Jul 17; 18(1):195-201. PubMed ID: 17549368
    [Abstract] [Full Text] [Related]

  • 24. Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry.
    Verdier-Pinard P, Wang F, Martello L, Burd B, Orr GA, Horwitz SB.
    Biochemistry; 2003 May 13; 42(18):5349-57. PubMed ID: 12731876
    [Abstract] [Full Text] [Related]

  • 25. Random mutagenesis of β-tubulin defines a set of dispersed mutations that confer paclitaxel resistance.
    Yin S, Zeng C, Hari M, Cabral F.
    Pharm Res; 2012 Nov 13; 29(11):2994-3006. PubMed ID: 22669706
    [Abstract] [Full Text] [Related]

  • 26. Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified beta-tubulin isotypes.
    Derry WB, Wilson L, Khan IA, Luduena RF, Jordan MA.
    Biochemistry; 1997 Mar 25; 36(12):3554-62. PubMed ID: 9132006
    [Abstract] [Full Text] [Related]

  • 27. Control mechanisms of tubulin gene expression in Trypanosoma cruzi.
    da Silva RA, Bartholomeu DC, Teixeira SM.
    Int J Parasitol; 2006 Jan 25; 36(1):87-96. PubMed ID: 16233898
    [Abstract] [Full Text] [Related]

  • 28. Increased levels of tyrosinated alpha-, beta(III)-, and beta(IV)-tubulin isotypes in paclitaxel-resistant MCF-7 breast cancer cells.
    Banerjee A.
    Biochem Biophys Res Commun; 2002 Apr 26; 293(1):598-601. PubMed ID: 12054644
    [Abstract] [Full Text] [Related]

  • 29. beta-Tubulin mutations are associated with resistance to 2-methoxyestradiol in MDA-MB-435 cancer cells.
    Gökmen-Polar Y, Escuin D, Walls CD, Soule SE, Wang Y, Sanders KL, Lavallee TM, Wang M, Guenther BD, Giannakakou P, Sledge GW.
    Cancer Res; 2005 Oct 15; 65(20):9406-14. PubMed ID: 16230404
    [Abstract] [Full Text] [Related]

  • 30. Cyclostreptin (FR182877), an antitumor tubulin-polymerizing agent deficient in enhancing tubulin assembly despite its high affinity for the taxoid site.
    Edler MC, Buey RM, Gussio R, Marcus AI, Vanderwal CD, Sorensen EJ, Díaz JF, Giannakakou P, Hamel E.
    Biochemistry; 2005 Aug 30; 44(34):11525-38. PubMed ID: 16114889
    [Abstract] [Full Text] [Related]

  • 31. BetaIII-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability.
    Kamath K, Wilson L, Cabral F, Jordan MA.
    J Biol Chem; 2005 Apr 01; 280(13):12902-7. PubMed ID: 15695826
    [Abstract] [Full Text] [Related]

  • 32. Identification and characterization of an intermediate taxol binding site within microtubule nanopores and a mechanism for tubulin isotype binding selectivity.
    Freedman H, Huzil JT, Luchko T, Ludueña RF, Tuszynski JA.
    J Chem Inf Model; 2009 Feb 01; 49(2):424-36. PubMed ID: 19434843
    [Abstract] [Full Text] [Related]

  • 33. Microtubule disruption induced in vivo by alkylation of beta-tubulin by 1-aryl-3-(2-chloroethyl)ureas, a novel class of soft alkylating agents.
    Legault J, Gaulin JF, Mounetou E, Bolduc S, Lacroix J, Poyet P, Gaudreault RC.
    Cancer Res; 2000 Feb 15; 60(4):985-92. PubMed ID: 10706114
    [Abstract] [Full Text] [Related]

  • 34. Overexpression of class I, II or IVb beta-tubulin isotypes in CHO cells is insufficient to confer resistance to paclitaxel.
    Blade K, Menick DR, Cabral F.
    J Cell Sci; 1999 Jul 15; 112 ( Pt 13)():2213-21. PubMed ID: 10362551
    [Abstract] [Full Text] [Related]

  • 35. Estramustine depolymerizes microtubules by binding to tubulin.
    Dahllöf B, Billström A, Cabral F, Hartley-Asp B.
    Cancer Res; 1993 Oct 01; 53(19):4573-81. PubMed ID: 8402630
    [Abstract] [Full Text] [Related]

  • 36. Mutagenesis of beta-tubulin cysteine residues in Saccharomyces cerevisiae: mutation of cysteine 354 results in cold-stable microtubules.
    Gupta ML, Bode CJ, Dougherty CA, Marquez RT, Himes RH.
    Cell Motil Cytoskeleton; 2001 Jun 01; 49(2):67-77. PubMed ID: 11443737
    [Abstract] [Full Text] [Related]

  • 37. Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity.
    Buey RM, Barasoain I, Jackson E, Meyer A, Giannakakou P, Paterson I, Mooberry S, Andreu JM, Díaz JF.
    Chem Biol; 2005 Dec 01; 12(12):1269-79. PubMed ID: 16356844
    [Abstract] [Full Text] [Related]

  • 38. Taxol resistance among the different histological subtypes of ovarian cancer may be associated with the expression of class III beta-tubulin.
    Umezu T, Shibata K, Kajiyama H, Terauchi M, Ino K, Nawa A, Kikkawa F.
    Int J Gynecol Pathol; 2008 Apr 01; 27(2):207-12. PubMed ID: 18317222
    [Abstract] [Full Text] [Related]

  • 39. Cytoskeletons and antimitotic agents developed in Japan.
    Nishio K, Saijo N.
    Anticancer Drug Des; 1999 Apr 01; 14(2):133-41. PubMed ID: 10405640
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  • 40. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin.
    Gupta K, Bishop J, Peck A, Brown J, Wilson L, Panda D.
    Biochemistry; 2004 Jun 01; 43(21):6645-55. PubMed ID: 15157098
    [Abstract] [Full Text] [Related]

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