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Journal Abstract Search


202 related items for PubMed ID: 16393727

  • 1. Roflumilast inhibition of pulmonary leukotriene production and bronchoconstriction in ovalbumin-sensitized and -challenged Guinea pigs.
    Wollin L, Marx D, Wohlsen A, Beume R.
    J Asthma; 2005 Dec; 42(10):873-8. PubMed ID: 16393727
    [Abstract] [Full Text] [Related]

  • 2. In vivo efficacy in airway disease models of roflumilast, a novel orally active PDE4 inhibitor.
    Bundschuh DS, Eltze M, Barsig J, Wollin L, Hatzelmann A, Beume R.
    J Pharmacol Exp Ther; 2001 Apr; 297(1):280-90. PubMed ID: 11259555
    [Abstract] [Full Text] [Related]

  • 3. Effect of inhaled roflumilast on the prevention and resolution of allergen-induced late phase airflow obstruction in Brown Norway rats.
    Chapman RW, House A, Jones H, Richard J, Celly C, Prelusky D, Ting P, Hunter JC, Lamca J, Phillips JE.
    Eur J Pharmacol; 2007 Oct 01; 571(2-3):215-21. PubMed ID: 17610865
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  • 5. Inhaled montelukast inhibits cysteinyl-leukotriene-induced bronchoconstriction in ovalbumin-sensitized guinea-pigs: the potential as a new asthma medication.
    Muraki M, Imbe S, Sato R, Ikeda Y, Yamagata S, Iwanaga T, Tohda Y.
    Int Immunopharmacol; 2009 Oct 01; 9(11):1337-41. PubMed ID: 19706339
    [Abstract] [Full Text] [Related]

  • 6. L-454,560, a potent and selective PDE4 inhibitor with in vivo efficacy in animal models of asthma and cognition.
    Huang Z, Dias R, Jones T, Liu S, Styhler A, Claveau D, Otu F, Ng K, Laliberte F, Zhang L, Goetghebeur P, Abraham WM, Macdonald D, Dubé D, Gallant M, Lacombe P, Girard Y, Young RN, Turner MJ, Nicholson DW, Mancini JA.
    Biochem Pharmacol; 2007 Jun 15; 73(12):1971-81. PubMed ID: 17428447
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  • 8. Inhibition of antigen-induced bronchoconstriction and eosinophil infiltration in the guinea pig by the cyclic AMP-specific phosphodiesterase inhibitor, rolipram.
    Underwood DC, Osborn RR, Novak LB, Matthews JK, Newsholme SJ, Undem BJ, Hand JM, Torphy TJ.
    J Pharmacol Exp Ther; 1993 Jul 15; 266(1):306-13. PubMed ID: 8392555
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  • 10. The inhibitory effect of TMK688, a novel anti-allergic drug having both 5-lipoxygenase inhibitory activity and anti-histamine activity, against bronchoconstriction, leukotriene production and inflammatory cell infiltration in sensitized guinea pigs.
    Tohda Y, Nakajima S, Shizawa T, Maeda K, Ohmori S, Satoh H, Ishii T, Kamitani T.
    Clin Exp Allergy; 1997 Jan 15; 27(1):110-8. PubMed ID: 9117875
    [Abstract] [Full Text] [Related]

  • 11. Influence of roflumilast on airway reactivity and apoptosis in ovalbumin-sensitized Guinea pigs.
    Medvedova I, Prso M, Eichlerova A, Mokra D, Mikolka P, Mokry J.
    Adv Exp Med Biol; 2015 Jan 15; 838():11-8. PubMed ID: 25310957
    [Abstract] [Full Text] [Related]

  • 12. Effect of the lipoxygenase inhibitor N-hydroxy-N-(6-methoxy-3,4-dihydro-2-naphthylmethyl)urea on bronchoconstriction and lung vascular permeability in anaphylactic guinea pigs.
    Geist C, Schneider J, Zimmer O.
    Arzneimittelforschung; 1995 Feb 15; 45(2):155-8. PubMed ID: 7710438
    [Abstract] [Full Text] [Related]

  • 13. Dose dependent effects of tadalafil and roflumilast on ovalbumin-induced airway hyperresponsiveness in guinea pigs.
    Urbanova A, Medvedova I, Kertys M, Mikolka P, Kosutova P, Mokra D, Mokrý J.
    Exp Lung Res; 2017 Feb 15; 43(9-10):407-416. PubMed ID: 29220595
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  • 14. Effects of ciclamilast, a new PDE 4 PDE4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma.
    Deng YM, Xie QM, Tang HF, Sun JG, Deng JF, Chen JQ, Yang SY.
    Eur J Pharmacol; 2006 Oct 10; 547(1-3):125-35. PubMed ID: 16956605
    [Abstract] [Full Text] [Related]

  • 15. Interactions among three classes of mediators explain antigen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung.
    Sundström E, Låstbom L, Ryrfeldt A, Dahlén SE.
    J Pharmacol Exp Ther; 2003 Oct 10; 307(1):408-18. PubMed ID: 12954791
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  • 17. Effects of the phosphodiesterase type 4 inhibitor roflumilast on early and late allergic response and airway hyperresponsiveness in Aspergillus-fumigatus-sensitized mice.
    Hoymann HG, Wollin L, Muller M, Korolewitz R, Krug N, Braun A, Beume R.
    Pharmacology; 2009 Oct 10; 83(3):188-95. PubMed ID: 19176983
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  • 18. Roflumilast Altana Pharma.
    Reid P.
    Curr Opin Investig Drugs; 2002 Aug 10; 3(8):1165-70. PubMed ID: 12211409
    [Abstract] [Full Text] [Related]

  • 19. The influence of endogenous catecholamines on the inhibitory effects of rolipram against early- and late-phase response to antigen in the guinea pig.
    Underwood DC, Matthews JK, Osborn RR, Bochnowicz S, Torphy TJ.
    J Pharmacol Exp Ther; 1997 Jan 10; 280(1):210-9. PubMed ID: 8996198
    [Abstract] [Full Text] [Related]

  • 20. A comparison of antiasthma drugs between acute and chronic ovalbumin-challenged guinea-pig models of asthma.
    Evans RL, Nials AT, Knowles RG, Kidd EJ, Ford WR, Broadley KJ.
    Pulm Pharmacol Ther; 2012 Dec 10; 25(6):453-64. PubMed ID: 23046662
    [Abstract] [Full Text] [Related]


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