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3. Structural and functional characterization of mutants of recombinant single-chain urokinase-type plasminogen activator obtained by site-specific mutagenesis of Lys158, Ile159 and Ile160. Lijnen HR, Nelles L, Van Hoef B, Demarsin E, Collen D. Eur J Biochem; 1988 Nov 15; 177(3):575-82. PubMed ID: 2973984 [Abstract] [Full Text] [Related]
4. The effects of fibrinogen and its cleavage products on the kinetics of plasminogen activation by urokinase and subsequent plasmin activity. Lucas MA, Straight DL, Fretto LJ, McKee PA. J Biol Chem; 1983 Oct 25; 258(20):12171-7. PubMed ID: 6226655 [Abstract] [Full Text] [Related]
6. Pro-urokinase: a study of its stability in plasma and of a mechanism for its selective fibrinolytic effect. Pannell R, Gurewich V. Blood; 1986 May 25; 67(5):1215-23. PubMed ID: 3083889 [Abstract] [Full Text] [Related]
7. The kinetics of plasminogen activation by thrombin-cleaved pro-urokinase and promotion of its activity by fibrin fragment E-2 and by tissue plasminogen activator. Liu JN, Gurewich V. Blood; 1993 Feb 15; 81(4):980-7. PubMed ID: 8428004 [Abstract] [Full Text] [Related]
8. Mechanism of the enhanced intrinsic activity of single-chain urokinase-type plasminogen activator during ongoing fibrinolysis. Fleury V, Lijnen HR, Anglés-Cano E. J Biol Chem; 1993 Sep 05; 268(25):18554-9. PubMed ID: 8103046 [Abstract] [Full Text] [Related]
9. Plasminogen activation with single-chain urokinase-type plasminogen activator (scu-PA). Studies with active site mutagenized plasminogen (Ser740----Ala) and plasmin-resistant scu-PA (Lys158----Glu). Lijnen HR, Van Hoef B, Nelles L, Collen D. J Biol Chem; 1990 Mar 25; 265(9):5232-6. PubMed ID: 1969415 [Abstract] [Full Text] [Related]
10. Activation of plasminogen by pro-urokinase. I. Mechanism. Lijnen HR, Zamarron C, Blaber M, Winkler ME, Collen D. J Biol Chem; 1986 Jan 25; 261(3):1253-8. PubMed ID: 2935528 [Abstract] [Full Text] [Related]
11. Activation of plasminogen by pro-urokinase. II. Kinetics. Collen D, Zamarron C, Lijnen HR, Hoylaerts M. J Biol Chem; 1986 Jan 25; 261(3):1259-66. PubMed ID: 2935529 [Abstract] [Full Text] [Related]
12. Activation of plasminogen by single-chain urokinase or by two-chain urokinase--a demonstration that single-chain urokinase has a low catalytic activity (pro-urokinase). Pannell R, Gurewich V. Blood; 1987 Jan 25; 69(1):22-6. PubMed ID: 3790724 [Abstract] [Full Text] [Related]
13. Plasminogen activation by single-chain urokinase in functional isolation. A kinetic study. Ellis V, Scully MF, Kakkar VV. J Biol Chem; 1987 Nov 05; 262(31):14998-5003. PubMed ID: 3667621 [Abstract] [Full Text] [Related]
14. The effect of the carboxy-terminal lysine of urokinase on the catalysis of plasminogen activation. Lenich C, Pannell R, Gurewich V. Thromb Res; 1991 Oct 01; 64(1):69-80. PubMed ID: 1776140 [Abstract] [Full Text] [Related]
15. Single-chain urokinase-type plasminogen activator does not possess measurable intrinsic amidolytic or plasminogen activator activities. Husain SS. Biochemistry; 1991 Jun 11; 30(23):5797-805. PubMed ID: 1828371 [Abstract] [Full Text] [Related]
16. Characterization of the binding of urokinase-type plasminogen activator (u-PA) to plasminogen, to plasminogen-activator inhibitor-1 and to the u-PA receptor. Lijnen HR, De Cock F, Collen D. Eur J Biochem; 1994 Sep 01; 224(2):567-74. PubMed ID: 7925373 [Abstract] [Full Text] [Related]
17. Kinetic analyses of the activation of Glu-plasminogen by urokinase in the presence of fibrin, fibrinogen or its degradation products. Watahiki Y, Takada Y, Takada A. Thromb Res; 1987 Apr 01; 46(1):9-18. PubMed ID: 3590117 [Abstract] [Full Text] [Related]
18. Characterization of the high-affinity interaction between human plasminogen and pro-urokinase. Lijnen HR, Zamarron C, Collen D. Eur J Biochem; 1985 Jul 01; 150(1):141-4. PubMed ID: 3926492 [Abstract] [Full Text] [Related]
19. Activation of fibrin-bound plasminogen by pro-urokinase and its complementariness with that by tissue plasminogen activator. Gurewich V. Enzyme; 1988 Jul 01; 40(2-3):97-108. PubMed ID: 2971533 [Abstract] [Full Text] [Related]
20. Proteolytic cleavage of single-chain pro-urokinase induces conformational change which follows activation of the zymogen and reduction of its high affinity for fibrin. Kasai S, Arimura H, Nishida M, Suyama T. J Biol Chem; 1985 Oct 05; 260(22):12377-81. PubMed ID: 3930494 [Abstract] [Full Text] [Related] Page: [Next] [New Search]