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Journal Abstract Search


473 related items for PubMed ID: 1639793

  • 1. Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells.
    Arora N, Klimpel KR, Singh Y, Leppla SH.
    J Biol Chem; 1992 Aug 05; 267(22):15542-8. PubMed ID: 1639793
    [Abstract] [Full Text] [Related]

  • 2. Residues 1-254 of anthrax toxin lethal factor are sufficient to cause cellular uptake of fused polypeptides.
    Arora N, Leppla SH.
    J Biol Chem; 1993 Feb 15; 268(5):3334-41. PubMed ID: 8429009
    [Abstract] [Full Text] [Related]

  • 3. Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity.
    Chaudhary VK, Jinno Y, FitzGerald D, Pastan I.
    Proc Natl Acad Sci U S A; 1990 Jan 15; 87(1):308-12. PubMed ID: 2104981
    [Abstract] [Full Text] [Related]

  • 4. Anthrax toxin-mediated delivery of the Pseudomonas exotoxin A enzymatic domain to the cytosol of tumor cells via cleavable ubiquitin fusions.
    Bachran C, Morley T, Abdelazim S, Fattah RJ, Liu S, Leppla SH.
    mBio; 2013 Apr 30; 4(3):e00201-13. PubMed ID: 23631917
    [Abstract] [Full Text] [Related]

  • 5. Fusions of anthrax toxin lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells.
    Arora N, Leppla SH.
    Infect Immun; 1994 Nov 30; 62(11):4955-61. PubMed ID: 7927776
    [Abstract] [Full Text] [Related]

  • 6. Translocation mediated by domain II of Pseudomonas exotoxin A: transport of barnase into the cytosol.
    Prior TI, FitzGerald DJ, Pastan I.
    Biochemistry; 1992 Apr 14; 31(14):3555-9. PubMed ID: 1567815
    [Abstract] [Full Text] [Related]

  • 7. A recombinant form of Pseudomonas exotoxin directed at the epidermal growth factor receptor that is cytotoxic without requiring proteolytic processing.
    Theuer CP, FitzGerald D, Pastan I.
    J Biol Chem; 1992 Aug 25; 267(24):16872-7. PubMed ID: 1512230
    [Abstract] [Full Text] [Related]

  • 8. Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol.
    Ogata M, Fryling CM, Pastan I, FitzGerald DJ.
    J Biol Chem; 1992 Dec 15; 267(35):25396-401. PubMed ID: 1460035
    [Abstract] [Full Text] [Related]

  • 9. Alanine scanning mutagenesis identifies surface amino acids on domain II of Pseudomonas exotoxin required for cytotoxicity, proper folding, and secretion into periplasm.
    Kasturi S, Kihara A, FitzGerald D, Pastan I.
    J Biol Chem; 1992 Nov 15; 267(32):23427-33. PubMed ID: 1429683
    [Abstract] [Full Text] [Related]

  • 10. Domain II mutants of Pseudomonas exotoxin deficient in translocation.
    Jinno Y, Ogata M, Chaudhary VK, Willingham MC, Adhya S, FitzGerald D, Pastan I.
    J Biol Chem; 1989 Sep 25; 264(27):15953-9. PubMed ID: 2506173
    [Abstract] [Full Text] [Related]

  • 11. Barnase toxin: a new chimeric toxin composed of pseudomonas exotoxin A and barnase.
    Prior TI, FitzGerald DJ, Pastan I.
    Cell; 1991 Mar 08; 64(5):1017-23. PubMed ID: 1900455
    [Abstract] [Full Text] [Related]

  • 12. Protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus.
    Milne JC, Blanke SR, Hanna PC, Collier RJ.
    Mol Microbiol; 1995 Feb 08; 15(4):661-6. PubMed ID: 7783638
    [Abstract] [Full Text] [Related]

  • 13. Systematic comparison of single-chain Fv antibody-fusion toxin constructs containing Pseudomonas Exotoxin A or saporin produced in different microbial expression systems.
    Della Cristina P, Castagna M, Lombardi A, Barison E, Tagliabue G, Ceriotti A, Koutris I, Di Leandro L, Giansanti F, Vago R, Ippoliti R, Flavell SU, Flavell DJ, Colombatti M, Fabbrini MS.
    Microb Cell Fact; 2015 Feb 13; 14():19. PubMed ID: 25889802
    [Abstract] [Full Text] [Related]

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  • 15. Internalization and translocation of a new chimeric protein composed of Pseudomonas aeruginosa exotoxin A and mouse dihydrofolate reductase as a model system.
    Guidi-Rontani C.
    Protein Eng; 1996 Jul 13; 9(7):611-6. PubMed ID: 8844833
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  • 17. Redirecting Pseudomonas exotoxin.
    FitzGerald D, Pastan I.
    Semin Cell Biol; 1991 Feb 13; 2(1):31-7. PubMed ID: 1954341
    [Abstract] [Full Text] [Related]

  • 18. Identification of the carboxyl-terminal amino acids important for the ADP-ribosylation activity of Pseudomonas exotoxin A.
    Chow JT, Chen MS, Wu HC, Hwang J.
    J Biol Chem; 1989 Nov 05; 264(31):18818-23. PubMed ID: 2553721
    [Abstract] [Full Text] [Related]

  • 19. Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases.
    Gordon VM, Klimpel KR, Arora N, Henderson MA, Leppla SH.
    Infect Immun; 1995 Jan 05; 63(1):82-7. PubMed ID: 7806387
    [Abstract] [Full Text] [Related]

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