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196 related items for PubMed ID: 16405966

  • 1. Thiorphan, tiopronin, and related analogs as substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase (PAM).
    McIntyre NR, Lowe EW, Chew GH, Owen TC, Merkler DJ.
    FEBS Lett; 2006 Jan 23; 580(2):521-32. PubMed ID: 16405966
    [Abstract] [Full Text] [Related]

  • 2. The enzymatic formation of novel bile acid primary amides.
    King L, Barnes S, Glufke U, Henz ME, Kirk M, Merkler KA, Vederas JC, Wilcox BJ, Merkler DJ.
    Arch Biochem Biophys; 2000 Feb 15; 374(2):107-17. PubMed ID: 10666288
    [Abstract] [Full Text] [Related]

  • 3. Ubiquitin and ubiquitin-derived peptides as substrates for peptidylglycine alpha-amidating monooxygenase.
    Chew GH, Galloway LC, McIntyre NR, Schroder LA, Richards KM, Miller SA, Wright DW, Merkler DJ.
    FEBS Lett; 2005 Aug 29; 579(21):4678-84. PubMed ID: 16098968
    [Abstract] [Full Text] [Related]

  • 4. Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin.
    DeBlassio JL, deLong MA, Glufke U, Kulathila R, Merkler KA, Vederas JC, Merkler DJ.
    Arch Biochem Biophys; 2000 Nov 01; 383(1):46-55. PubMed ID: 11097175
    [Abstract] [Full Text] [Related]

  • 5. Fatty acid amide biosynthesis: a possible new role for peptidylglycine alpha-amidating enzyme and acyl-coenzyme A: glycine N-acyltransferase.
    Merkler DJ, Merkler KA, Stern W, Fleming FF.
    Arch Biochem Biophys; 1996 Jun 15; 330(2):430-4. PubMed ID: 8660675
    [Abstract] [Full Text] [Related]

  • 6. Investigation of the pathway for inter-copper electron transfer in peptidylglycine alpha-amidating monooxygenase.
    Francisco WA, Wille G, Smith AJ, Merkler DJ, Klinman JP.
    J Am Chem Soc; 2004 Oct 20; 126(41):13168-9. PubMed ID: 15479039
    [Abstract] [Full Text] [Related]

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  • 8. Inhibition of peptidylglycine alpha-amidating monooxygenase by exploitation of factors affecting the stability and ease of formation of glycyl radicals.
    Barratt BJ, Easton CJ, Henry DJ, Li IH, Radom L, Simpson JS.
    J Am Chem Soc; 2004 Oct 20; 126(41):13306-11. PubMed ID: 15479085
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  • 10. Use of reversed phase HP liquid chromatography to assay conversion of N-acylglycines to primary fatty acid amides by peptidylglycine-alpha-amidating monooxygenase.
    Carpenter T, Poore DD, Gee AJ, Deshpande P, Merkler DJ, Johnson ME.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2004 Sep 25; 809(1):15-21. PubMed ID: 15282088
    [Abstract] [Full Text] [Related]

  • 11. Evidence for substrate preorganization in the peptidylglycine α-amidating monooxygenase reaction describing the contribution of ground state structure to hydrogen tunneling.
    McIntyre NR, Lowe EW, Belof JL, Ivkovic M, Shafer J, Space B, Merkler DJ.
    J Am Chem Soc; 2010 Nov 24; 132(46):16393-402. PubMed ID: 21043511
    [Abstract] [Full Text] [Related]

  • 12. Mechanistic investigation of peptidylglycine alpha-hydroxylating monooxygenase via intrinsic tryptophan fluorescence and mutagenesis.
    Bell J, El Meskini R, D'Amato D, Mains RE, Eipper BA.
    Biochemistry; 2003 Jun 17; 42(23):7133-42. PubMed ID: 12795609
    [Abstract] [Full Text] [Related]

  • 13. Peptide alpha-amidation and peptidylglycine alpha-hydroxylating monooxygenase: control by disulfiram.
    Mueller GP, Husten EJ, Mains RE, Eipper BA.
    Mol Pharmacol; 1993 Nov 17; 44(5):972-80. PubMed ID: 8246921
    [Abstract] [Full Text] [Related]

  • 14. Dioxygen binds end-on to mononuclear copper in a precatalytic enzyme complex.
    Prigge ST, Eipper BA, Mains RE, Amzel LM.
    Science; 2004 May 07; 304(5672):864-7. PubMed ID: 15131304
    [Abstract] [Full Text] [Related]

  • 15. 60 YEARS OF POMC: From POMC and α-MSH to PAM, molecular oxygen, copper, and vitamin C.
    Kumar D, Mains RE, Eipper BA.
    J Mol Endocrinol; 2016 May 07; 56(4):T63-76. PubMed ID: 26667899
    [Abstract] [Full Text] [Related]

  • 16. Oleic acid derived metabolites in mouse neuroblastoma N18TG2 cells.
    Merkler DJ, Chew GH, Gee AJ, Merkler KA, Sorondo JP, Johnson ME.
    Biochemistry; 2004 Oct 05; 43(39):12667-74. PubMed ID: 15449956
    [Abstract] [Full Text] [Related]

  • 17. Peptidyl-glycine alpha-amidating monooxygenase targeting and shaping of atrial secretory vesicles: inhibition by mutated N-terminal ProANP and PBA.
    Labrador V, Brun C, König S, Roatti A, Baertschi AJ.
    Circ Res; 2004 Dec 10; 95(12):e98-109. PubMed ID: 15539631
    [Abstract] [Full Text] [Related]

  • 18. Structural and functional investigations on the role of zinc in bifunctional rat peptidylglycine alpha-amidating enzyme.
    Bell J, Ash DE, Snyder LM, Kulathila R, Blackburn NJ, Merkler DJ.
    Biochemistry; 1997 Dec 23; 36(51):16239-46. PubMed ID: 9405058
    [Abstract] [Full Text] [Related]

  • 19. Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs.
    McIntyre NR, Lowe EW, Battistini MR, Leahy JW, Merkler DJ.
    J Enzyme Inhib Med Chem; 2016 Aug 23; 31(4):551-62. PubMed ID: 26024288
    [Abstract] [Full Text] [Related]

  • 20. Glutathione, S-substituted glutathiones, and leukotriene C4 as substrates for peptidylglycine alpha-amidating monooxygenase.
    Miller LA, Baumgart LE, Chew GH, deLong MA, Galloway LC, Jung KW, Merkler KA, Nagle AS, Poore DD, Yoon CH, Merkler DJ.
    Arch Biochem Biophys; 2003 Apr 01; 412(1):3-12. PubMed ID: 12646261
    [Abstract] [Full Text] [Related]

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