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Journal Abstract Search


715 related items for PubMed ID: 16407241

  • 1. Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation.
    Vaughan DJ, Millman EE, Godines V, Friedman J, Tran TM, Dai W, Knoll BJ, Clark RB, Moore RH.
    J Biol Chem; 2006 Mar 17; 281(11):7684-92. PubMed ID: 16407241
    [Abstract] [Full Text] [Related]

  • 2. Localization of the sites mediating desensitization of the beta(2)-adrenergic receptor by the GRK pathway.
    Seibold A, Williams B, Huang ZF, Friedman J, Moore RH, Knoll BJ, Clark RB.
    Mol Pharmacol; 2000 Nov 17; 58(5):1162-73. PubMed ID: 11040066
    [Abstract] [Full Text] [Related]

  • 3. Characterization of agonist stimulation of cAMP-dependent protein kinase and G protein-coupled receptor kinase phosphorylation of the beta2-adrenergic receptor using phosphoserine-specific antibodies.
    Tran TM, Friedman J, Qunaibi E, Baameur F, Moore RH, Clark RB.
    Mol Pharmacol; 2004 Jan 17; 65(1):196-206. PubMed ID: 14722251
    [Abstract] [Full Text] [Related]

  • 4. Beta-arrestin mediates desensitization and internalization but does not affect dephosphorylation of the thyrotropin-releasing hormone receptor.
    Jones BW, Hinkle PM.
    J Biol Chem; 2005 Nov 18; 280(46):38346-54. PubMed ID: 16183993
    [Abstract] [Full Text] [Related]

  • 5. Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase.
    Freedman NJ, Liggett SB, Drachman DE, Pei G, Caron MG, Lefkowitz RJ.
    J Biol Chem; 1995 Jul 28; 270(30):17953-61. PubMed ID: 7629102
    [Abstract] [Full Text] [Related]

  • 6. beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor.
    Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, Madabushi S, Reiter E, Premont RT, Lichtarge O, Lefkowitz RJ.
    J Biol Chem; 2006 Jan 13; 281(2):1261-73. PubMed ID: 16280323
    [Abstract] [Full Text] [Related]

  • 7. Effect of different G protein-coupled receptor kinases on phosphorylation and desensitization of the alpha1B-adrenergic receptor.
    Diviani D, Lattion AL, Larbi N, Kunapuli P, Pronin A, Benovic JL, Cotecchia S.
    J Biol Chem; 1996 Mar 01; 271(9):5049-58. PubMed ID: 8617782
    [Abstract] [Full Text] [Related]

  • 8. Interaction with beta-arrestin determines the difference in internalization behavor between beta1- and beta2-adrenergic receptors.
    Shiina T, Kawasaki A, Nagao T, Kurose H.
    J Biol Chem; 2000 Sep 15; 275(37):29082-90. PubMed ID: 10862778
    [Abstract] [Full Text] [Related]

  • 9. Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways.
    Rapacciuolo A, Suvarna S, Barki-Harrington L, Luttrell LM, Cong M, Lefkowitz RJ, Rockman HA.
    J Biol Chem; 2003 Sep 12; 278(37):35403-11. PubMed ID: 12821660
    [Abstract] [Full Text] [Related]

  • 10. A phosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for beta-arrestin-mediated ERK activation.
    Kara E, Crépieux P, Gauthier C, Martinat N, Piketty V, Guillou F, Reiter E.
    Mol Endocrinol; 2006 Nov 12; 20(11):3014-26. PubMed ID: 16887887
    [Abstract] [Full Text] [Related]

  • 11. Regulation of corticotropin-releasing hormone receptor type 1alpha signaling: structural determinants for G protein-coupled receptor kinase-mediated phosphorylation and agonist-mediated desensitization.
    Teli T, Markovic D, Levine MA, Hillhouse EW, Grammatopoulos DK.
    Mol Endocrinol; 2005 Feb 12; 19(2):474-90. PubMed ID: 15498832
    [Abstract] [Full Text] [Related]

  • 12. The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation.
    Estall JL, Koehler JA, Yusta B, Drucker DJ.
    J Biol Chem; 2005 Jun 10; 280(23):22124-34. PubMed ID: 15817468
    [Abstract] [Full Text] [Related]

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  • 14. Desensitization of beta2-adrenergic receptors with mutations of the proposed G protein-coupled receptor kinase phosphorylation sites.
    Seibold A, January BG, Friedman J, Hipkin RW, Clark RB.
    J Biol Chem; 1998 Mar 27; 273(13):7637-42. PubMed ID: 9516468
    [Abstract] [Full Text] [Related]

  • 15. G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer.
    Violin JD, Ren XR, Lefkowitz RJ.
    J Biol Chem; 2006 Jul 21; 281(29):20577-88. PubMed ID: 16687412
    [Abstract] [Full Text] [Related]

  • 16. Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors.
    Pippig S, Andexinger S, Daniel K, Puzicha M, Caron MG, Lefkowitz RJ, Lohse MJ.
    J Biol Chem; 1993 Feb 15; 268(5):3201-8. PubMed ID: 8381421
    [Abstract] [Full Text] [Related]

  • 17. Rapid agonist-induced desensitization and internalization of the A(2B) adenosine receptor is mediated by a serine residue close to the COOH terminus.
    Matharu AL, Mundell SJ, Benovic JL, Kelly E.
    J Biol Chem; 2001 Aug 10; 276(32):30199-207. PubMed ID: 11333255
    [Abstract] [Full Text] [Related]

  • 18. G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR.
    Miller WE, Houtz DA, Nelson CD, Kolattukudy PE, Lefkowitz RJ.
    J Biol Chem; 2003 Jun 13; 278(24):21663-71. PubMed ID: 12668664
    [Abstract] [Full Text] [Related]

  • 19. Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*.
    Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG.
    J Biol Chem; 2001 Jun 01; 276(22):19452-60. PubMed ID: 11279203
    [Abstract] [Full Text] [Related]

  • 20. Beta-arrestin1 and beta-arrestin2 are differentially required for phosphorylation-dependent and -independent internalization of delta-opioid receptors.
    Zhang X, Wang F, Chen X, Li J, Xiang B, Zhang YQ, Li BM, Ma L.
    J Neurochem; 2005 Oct 01; 95(1):169-78. PubMed ID: 16181421
    [Abstract] [Full Text] [Related]


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