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Journal Abstract Search

89 related items for PubMed ID: 16410307

  • 1. An aromatic environment in the vicinity of serine 281 is a structural requirement for thyrotropin receptor function.
    Jaeschke H, Neumann S, Kleinau G, Mueller S, Claus M, Krause G, Paschke R.
    Endocrinology; 2006 Apr; 147(4):1753-60. PubMed ID: 16410307
    [Abstract] [Full Text] [Related]

  • 2. Interactions between the extracellular domain and the extracellular loops as well as the 6th transmembrane domain are necessary for TSH receptor activation.
    Neumann S, Claus M, Paschke R.
    Eur J Endocrinol; 2005 Apr; 152(4):625-34. PubMed ID: 15817920
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  • 4. A free carboxylate oxygen in the side chain of position 674 in transmembrane domain 7 is necessary for TSH receptor activation.
    Neumann S, Krause G, Chey S, Paschke R.
    Mol Endocrinol; 2001 Aug; 15(8):1294-305. PubMed ID: 11463854
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  • 6. Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist.
    Vlaeminck-Guillem V, Ho SC, Rodien P, Vassart G, Costagliola S.
    Mol Endocrinol; 2002 Apr; 16(4):736-46. PubMed ID: 11923470
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  • 7. Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.
    Kosugi S, Okajima F, Ban T, Hidaka A, Shenker A, Kohn LD.
    Mol Endocrinol; 1993 Aug; 7(8):1009-20. PubMed ID: 7901757
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  • 8. Structural determinants for g protein activation and selectivity in the second intracellular loop of the thyrotropin receptor.
    Neumann S, Krause G, Claus M, Paschke R.
    Endocrinology; 2005 Jan; 146(1):477-85. PubMed ID: 15498884
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  • 9. Functional role of transmembrane helix 7 in the activation of the heptahelical lutropin receptor.
    Angelova K, Narayan P, Simon JP, Puett D.
    Mol Endocrinol; 2000 Apr; 14(4):459-71. PubMed ID: 10770485
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  • 10. Characterization of soluble, disulfide bond-stabilized, prokaryotically expressed human thyrotropin receptor ectodomain.
    Bobovnikova Y, Graves PN, Vlase H, Davies TF.
    Endocrinology; 1997 Feb; 138(2):588-93. PubMed ID: 9002990
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  • 11. Extended hormone binding site of the human thyroid stimulating hormone receptor: distinctive acidic residues in the hinge region are involved in bovine thyroid stimulating hormone binding and receptor activation.
    Mueller S, Kleinau G, Jaeschke H, Paschke R, Krause G.
    J Biol Chem; 2008 Jun 27; 283(26):18048-55. PubMed ID: 18441013
    [Abstract] [Full Text] [Related]

  • 12. On the functional importance of thyrotropin receptor intramolecular cleavage.
    Chazenbalk GD, Tanaka K, McLachlan SM, Rapoport B.
    Endocrinology; 1999 Oct 27; 140(10):4516-20. PubMed ID: 10499506
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  • 13. Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades.
    Parma J, Van Sande J, Swillens S, Tonacchera M, Dumont J, Vassart G.
    Mol Endocrinol; 1995 Jun 27; 9(6):725-33. PubMed ID: 8592518
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  • 14. The middle portion in the second cytoplasmic loop of the thyrotropin receptor plays a crucial role in adenylate cyclase activation.
    Kosugi S, Kohn LD, Akamizu T, Mori T.
    Mol Endocrinol; 1994 Apr 27; 8(4):498-509. PubMed ID: 7914349
    [Abstract] [Full Text] [Related]

  • 15. The hinge region of the TSH receptor stabilizes ligand binding and determines different signaling profiles of human and bovine TSH.
    Jaeschke H, Schaarschmidt J, Günther R, Mueller S.
    Endocrinology; 2011 Oct 27; 152(10):3986-96. PubMed ID: 21846801
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  • 17. An intracellular loop (IL2) residue confers different basal constitutive activities to the human lutropin receptor and human thyrotropin receptor through structural communication between IL2 and helix 6, via helix 3.
    Feng X, Müller T, Mizrachi D, Fanelli F, Segaloff DL.
    Endocrinology; 2008 Apr 27; 149(4):1705-17. PubMed ID: 18162522
    [Abstract] [Full Text] [Related]

  • 18. Folding of the recombinant human thyrotropin (TSH) receptor extracellular domain: identification of folded monomeric and tetrameric complexes that bind TSH receptor autoantibodies.
    Graves PN, Vlase H, Davies TF.
    Endocrinology; 1995 Feb 27; 136(2):521-7. PubMed ID: 7530646
    [Abstract] [Full Text] [Related]

  • 19. Characterization of a region of the lutropin receptor extracellular domain near transmembrane helix 1 that is important in ligand-mediated signaling.
    Alvarez CA, Narayan P, Huang J, Puett D.
    Endocrinology; 1999 Apr 27; 140(4):1775-82. PubMed ID: 10098515
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  • 20. Lysine 183 and glutamic acid 157 of the TSH receptor: two interacting residues with a key role in determining specificity toward TSH and human CG.
    Smits G, Govaerts C, Nubourgh I, Pardo L, Vassart G, Costagliola S.
    Mol Endocrinol; 2002 Apr 27; 16(4):722-35. PubMed ID: 11923469
    [Abstract] [Full Text] [Related]

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