These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. The design and synthesis of potent inhibitors of hepatitis C virus NS3-4A proteinase. Attwood MR, Bennett JM, Campbell AD, Canning GG, Carr MG, Conway E, Dunsdon RM, Greening JR, Jones PS, Kay PB, Handa BK, Hurst DN, Jennings NS, Jordan S, Keech E, O'Brien MA, Overton HA, King-Underwood J, Raynham TM, Stenson KP, Wilkinson CS, Wilkinson TC, Wilson FX. Antivir Chem Chemother; 1999 Sep 15; 10(5):259-73. PubMed ID: 10574181 [Abstract] [Full Text] [Related]
6. Synthesis and antiviral evaluation of a novel series of homoserine-based inhibitors of the hepatitis C virus NS3/4A serine protease. Alexandre FR, Brandt G, Caillet C, Chaves D, Convard T, Derock M, Gloux D, Griffon Y, Lallos L, Leroy F, Liuzzi M, Loi AG, Moulat L, Musiu C, Parsy C, Rahali H, Roques V, Seifer M, Standring D, Surleraux D. Bioorg Med Chem Lett; 2015 Sep 15; 25(18):3984-91. PubMed ID: 26231161 [Abstract] [Full Text] [Related]
10. Novel 2-oxoimidazolidine-4-carboxylic acid derivatives as hepatitis C virus NS3-4A serine protease inhibitors: synthesis, activity, and X-ray crystal structure of an enzyme inhibitor complex. Arasappan A, Njoroge FG, Parekh TN, Yang X, Pichardo J, Butkiewicz N, Prongay A, Yao N, Girijavallabhan V. Bioorg Med Chem Lett; 2004 Dec 06; 14(23):5751-5. PubMed ID: 15501035 [Abstract] [Full Text] [Related]
11. Discovery of GS-9451: an acid inhibitor of the hepatitis C virus NS3/4A protease. Sheng XC, Appleby T, Butler T, Cai R, Chen X, Cho A, Clarke MO, Cottell J, Delaney WE, Doerffler E, Link J, Ji M, Pakdaman R, Pyun HJ, Wu Q, Xu J, Kim CU. Bioorg Med Chem Lett; 2012 Apr 01; 22(7):2629-34. PubMed ID: 22366653 [Abstract] [Full Text] [Related]
12. Novel azapeptide inhibitors of hepatitis C virus serine protease. Bailey MD, Halmos T, Goudreau N, Lescop E, Llinàs-Brunet M. J Med Chem; 2004 Jul 15; 47(15):3788-99. PubMed ID: 15239657 [Abstract] [Full Text] [Related]
14. A novel high throughput screening assay for HCV NS3 serine protease inhibitors. Berdichevsky Y, Zemel R, Bachmatov L, Abramovich A, Koren R, Sathiyamoorthy P, Golan-Goldhirsh A, Tur-Kaspa R, Benhar I. J Virol Methods; 2003 Feb 15; 107(2):245-55. PubMed ID: 12505640 [Abstract] [Full Text] [Related]
15. Potent inhibitors of HCV-NS3 protease derived from boronic acids. Venkatraman S, Wu W, Prongay A, Girijavallabhan V, George Njoroge F. Bioorg Med Chem Lett; 2009 Jan 01; 19(1):180-3. PubMed ID: 19022670 [Abstract] [Full Text] [Related]
16. Synthesis and antiviral activity of novel HCV NS3 protease inhibitors with P4 capping groups. Li X, Liu Y, Zhang YK, Plattner JJ, Baker SJ, Bu W, Liu L, Zhou Y, Ding CZ, Zhang S, Kazmierski WM, Hamatake R, Duan M, Wright LL, Smith GK, Jarvest RL, Ji JJ, Cooper JP, Tallant MD, Crosby RM, Creech K, Wang A. Bioorg Med Chem Lett; 2012 Dec 15; 22(24):7351-6. PubMed ID: 23142614 [Abstract] [Full Text] [Related]
17. The hepatitis C virus NS3 proteinase: structure and function of a zinc-containing serine proteinase. De Francesco R, Pessi A, Steinkühler C. Antivir Ther; 1998 Dec 15; 3(Suppl 3):99-109. PubMed ID: 10726060 [Abstract] [Full Text] [Related]
18. Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease. Llinàs-Brunet M, Bailey M, Déziel R, Fazal G, Gorys V, Goulet S, Halmos T, Maurice R, Poirier M, Poupart MA, Rancourt J, Thibeault D, Wernic D, Lamarre D. Bioorg Med Chem Lett; 1998 Oct 06; 8(19):2719-24. PubMed ID: 9873610 [Abstract] [Full Text] [Related]