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183 related items for PubMed ID: 16434500

  • 1. Inhibition of hepatocarcinogenesis by the deletion of the p50 subunit of NF-kappaB in mice administered the peroxisome proliferator Wy-14,643.
    Glauert HP, Eyigor A, Tharappel JC, Cooper S, Lee EY, Spear BT.
    Toxicol Sci; 2006 Apr; 90(2):331-6. PubMed ID: 16434500
    [Abstract] [Full Text] [Related]

  • 2. Cell proliferation and apoptosis are altered in mice deficient in the NF-kappaB p50 subunit after treatment with the peroxisome proliferator ciprofibrate.
    Tharappel JC, Nalca A, Owens AB, Ghabrial L, Konz EC, Glauert HP, Spear BT.
    Toxicol Sci; 2003 Oct; 75(2):300-8. PubMed ID: 12883078
    [Abstract] [Full Text] [Related]

  • 3. WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase.
    Woods CG, Burns AM, Bradford BU, Ross PK, Kosyk O, Swenberg JA, Cunningham ML, Rusyn I.
    Toxicol Sci; 2007 Aug; 98(2):366-74. PubMed ID: 17483499
    [Abstract] [Full Text] [Related]

  • 4. Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.
    Rusyn I, Yamashina S, Segal BH, Schoonhoven R, Holland SM, Cattley RC, Swenberg JA, Thurman RG.
    Cancer Res; 2000 Sep 01; 60(17):4798-803. PubMed ID: 10987289
    [Abstract] [Full Text] [Related]

  • 5. Differences between the promoting activities of the peroxisome proliferator WY-14,643 and phenobarbital in rat liver.
    Cattley RC, Popp JA.
    Cancer Res; 1989 Jun 15; 49(12):3246-51. PubMed ID: 2566380
    [Abstract] [Full Text] [Related]

  • 6. Dietary glycine prevents increases in hepatocyte proliferation caused by the peroxisome proliferator WY-14,643.
    Rose ML, Germolec D, Arteel GE, Schoonhoven R, Thurman RG.
    Chem Res Toxicol; 1997 Oct 15; 10(10):1198-204. PubMed ID: 9348444
    [Abstract] [Full Text] [Related]

  • 7. WY-14,643-mediated promotion of hepatocarcinogenesis in connexin32-wild-type and connexin32-null mice.
    Moennikes O, Stahl S, Bannasch P, Buchmann A, Schwarz M.
    Carcinogenesis; 2003 Sep 15; 24(9):1561-5. PubMed ID: 12819187
    [Abstract] [Full Text] [Related]

  • 8. Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats.
    Marsman DS, Cattley RC, Conway JG, Popp JA.
    Cancer Res; 1988 Dec 01; 48(23):6739-44. PubMed ID: 3180084
    [Abstract] [Full Text] [Related]

  • 9. Role of the p50 subunit of NF-kappaB in vitamin E-induced changes in mice treated with the peroxisome proliferator, ciprofibrate.
    Calfee-Mason KG, Lee EY, Spear BT, Glauert HP.
    Food Chem Toxicol; 2008 Jun 01; 46(6):2062-73. PubMed ID: 18336980
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of the promotion of hepatocarcinogenesis by 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-kappa B in mice.
    Glauert HP, Tharappel JC, Banerjee S, Chan NL, Kania-Korwel I, Lehmler HJ, Lee EY, Robertson LW, Spear BT.
    Toxicol Appl Pharmacol; 2008 Oct 15; 232(2):302-8. PubMed ID: 18644402
    [Abstract] [Full Text] [Related]

  • 11. Activation of peroxisome proliferator-activated receptor alpha enhances apoptosis in the mouse liver.
    Xiao S, Anderson SP, Swanson C, Bahnemann R, Voss KA, Stauber AJ, Corton JC.
    Toxicol Sci; 2006 Aug 15; 92(2):368-77. PubMed ID: 16687391
    [Abstract] [Full Text] [Related]

  • 12. Effect of phenobarbital on hepatic cell proliferation and apoptosis in mice deficient in the p50 subunit of NF-kappaB.
    Tharappel JC, Spear BT, Glauert HP.
    Toxicol Appl Pharmacol; 2008 Feb 01; 226(3):338-44. PubMed ID: 17963809
    [Abstract] [Full Text] [Related]

  • 13. Mechanisms for the pancreatic oncogenic effects of the peroxisome proliferator Wyeth-14,643.
    Obourn JD, Frame SR, Bell RH, Longnecker DS, Elliott GS, Cook JC.
    Toxicol Appl Pharmacol; 1997 Aug 01; 145(2):425-36. PubMed ID: 9266817
    [Abstract] [Full Text] [Related]

  • 14. Evidence that reduction of hepatocyte growth factor (HGF) is not required for peroxisome proliferator-induced hepatocyte proliferation.
    Kiss A, Ortiz-Aguayo R, Sharp R, Merlino G, Thorgeirsson SS, Gonzalez FJ, Peters JM.
    Carcinogenesis; 2001 Jun 01; 22(6):975-9. PubMed ID: 11375907
    [Abstract] [Full Text] [Related]

  • 15. Epigenetic effects of the continuous exposure to peroxisome proliferator WY-14,643 in mouse liver are dependent upon peroxisome proliferator activated receptor alpha.
    Pogribny IP, Tryndyak VP, Woods CG, Witt SE, Rusyn I.
    Mutat Res; 2007 Dec 01; 625(1-2):62-71. PubMed ID: 17586532
    [Abstract] [Full Text] [Related]

  • 16. Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis.
    Hays T, Rusyn I, Burns AM, Kennett MJ, Ward JM, Gonzalez FJ, Peters JM.
    Carcinogenesis; 2005 Jan 01; 26(1):219-27. PubMed ID: 15447978
    [Abstract] [Full Text] [Related]

  • 17. Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes.
    Ammerschlaeger M, Beigel J, Klein KU, Mueller SO.
    Toxicol Sci; 2004 Apr 01; 78(2):229-40. PubMed ID: 14976357
    [Abstract] [Full Text] [Related]

  • 18. Mechanisms of extrahepatic tumor induction by peroxisome proliferators in male CD rats.
    Biegel LB, Hurtt ME, Frame SR, O'Connor JC, Cook JC.
    Toxicol Sci; 2001 Mar 01; 60(1):44-55. PubMed ID: 11222872
    [Abstract] [Full Text] [Related]

  • 19. Cell death and proliferation in NF-kappaB p50 knockout mouse after cerebral ischemia.
    Li J, Lu Z, Li WL, Yu SP, Wei L.
    Brain Res; 2008 Sep 16; 1230():281-9. PubMed ID: 18657523
    [Abstract] [Full Text] [Related]

  • 20. Toxic effects of fumonisin in mouse liver are independent of the peroxisome proliferator-activated receptor alpha.
    Voss KA, Liu J, Anderson SP, Dunn C, Miller JD, Owen JR, Riley RT, Bacon CW, Corton JC.
    Toxicol Sci; 2006 Jan 16; 89(1):108-19. PubMed ID: 16221962
    [Abstract] [Full Text] [Related]


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