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336 related items for PubMed ID: 16436379

  • 1. Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation.
    Yamasaki E, Wada A, Kumatori A, Nakagawa I, Funao J, Nakayama M, Hisatsune J, Kimura M, Moss J, Hirayama T.
    J Biol Chem; 2006 Apr 21; 281(16):11250-9. PubMed ID: 16436379
    [Abstract] [Full Text] [Related]

  • 2. Cellular vacuolation and mitochondrial cytochrome c release are independent outcomes of Helicobacter pylori vacuolating cytotoxin activity that are each dependent on membrane channel formation.
    Willhite DC, Cover TL, Blanke SR.
    J Biol Chem; 2003 Nov 28; 278(48):48204-9. PubMed ID: 13129933
    [Abstract] [Full Text] [Related]

  • 3. Endosome-mitochondria juxtaposition during apoptosis induced by H. pylori VacA.
    Calore F, Genisset C, Casellato A, Rossato M, Codolo G, Esposti MD, Scorrano L, de Bernard M.
    Cell Death Differ; 2010 Nov 28; 17(11):1707-16. PubMed ID: 20431599
    [Abstract] [Full Text] [Related]

  • 4. Helicobacter pylori VacA activates the p38/activating transcription factor 2-mediated signal pathway in AZ-521 cells.
    Nakayama M, Kimura M, Wada A, Yahiro K, Ogushi K, Niidome T, Fujikawa A, Shirasaka D, Aoyama N, Kurazono H, Noda M, Moss J, Hirayama T.
    J Biol Chem; 2004 Feb 20; 279(8):7024-8. PubMed ID: 14630932
    [Abstract] [Full Text] [Related]

  • 5. Subtilase cytotoxin induces apoptosis in HeLa cells by mitochondrial permeabilization via activation of Bax/Bak, independent of C/EBF-homologue protein (CHOP), Ire1alpha or JNK signaling.
    Yahiro K, Morinaga N, Moss J, Noda M.
    Microb Pathog; 2010 Oct 20; 49(4):153-63. PubMed ID: 20561923
    [Abstract] [Full Text] [Related]

  • 6. Helicobacter pylori VacA reduces the cellular expression of STAT3 and pro-survival Bcl-2 family proteins, Bcl-2 and Bcl-XL, leading to apoptosis in gastric epithelial cells.
    Matsumoto A, Isomoto H, Nakayama M, Hisatsune J, Nishi Y, Nakashima Y, Matsushima K, Kurazono H, Nakao K, Hirayama T, Kohno S.
    Dig Dis Sci; 2011 Apr 20; 56(4):999-1006. PubMed ID: 20927590
    [Abstract] [Full Text] [Related]

  • 7. Helicobacter pylori vacuolating cytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death.
    Jain P, Luo ZQ, Blanke SR.
    Proc Natl Acad Sci U S A; 2011 Sep 20; 108(38):16032-7. PubMed ID: 21903925
    [Abstract] [Full Text] [Related]

  • 8. Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells.
    Choi SY, Kim MJ, Kang CM, Bae S, Cho CK, Soh JW, Kim JH, Kang S, Chung HY, Lee YS, Lee SJ.
    J Biol Chem; 2006 Mar 17; 281(11):7049-59. PubMed ID: 16410245
    [Abstract] [Full Text] [Related]

  • 9. Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK.
    Ling YH, Lin R, Perez-Soler R.
    Mol Pharmacol; 2008 Sep 17; 74(3):793-806. PubMed ID: 18524889
    [Abstract] [Full Text] [Related]

  • 10. Dual effects of Helicobacter pylori vacuolating cytotoxin on human eosinophil apoptosis in early and late periods of stimulation.
    Kim JM, Kim JS, Lee JY, Sim YS, Kim YJ, Oh YK, Yoon HJ, Kang JS, Youn J, Kim N, Jung HC, Kim S.
    Eur J Immunol; 2010 Jun 17; 40(6):1651-62. PubMed ID: 20333629
    [Abstract] [Full Text] [Related]

  • 11. The multidomain proapoptotic molecules Bax and Bak are directly activated by heat.
    Pagliari LJ, Kuwana T, Bonzon C, Newmeyer DD, Tu S, Beere HM, Green DR.
    Proc Natl Acad Sci U S A; 2005 Dec 13; 102(50):17975-80. PubMed ID: 16330765
    [Abstract] [Full Text] [Related]

  • 12. Enterovirus 71 2B Induces Cell Apoptosis by Directly Inducing the Conformational Activation of the Proapoptotic Protein Bax.
    Cong H, Du N, Yang Y, Song L, Zhang W, Tien P.
    J Virol; 2016 Nov 01; 90(21):9862-9877. PubMed ID: 27558414
    [Abstract] [Full Text] [Related]

  • 13. Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin.
    Li Y, Wandinger-Ness A, Goldenring JR, Cover TL.
    Mol Biol Cell; 2004 Apr 01; 15(4):1946-59. PubMed ID: 14742715
    [Abstract] [Full Text] [Related]

  • 14. Involvement of syntaxin 7 in human gastric epithelial cell vacuolation induced by the Helicobacter pylori-produced cytotoxin VacA.
    Suzuki J, Ohnishi H, Wada A, Hirayama T, Ohno H, Ueda N, Yasuda H, Iiri T, Wada Y, Futai M, Mashima H.
    J Biol Chem; 2003 Jul 11; 278(28):25585-90. PubMed ID: 12730232
    [Abstract] [Full Text] [Related]

  • 15. Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release.
    Sheridan C, Delivani P, Cullen SP, Martin SJ.
    Mol Cell; 2008 Aug 22; 31(4):570-585. PubMed ID: 18722181
    [Abstract] [Full Text] [Related]

  • 16. Benzo(a)pyrene-7,8-diol-9,10-epoxide induced p53-independent necrosis via the mitochondria-associated pathway involving Bax and Bak activation.
    Zhang W, Liu N, Wang X, Jin X, Du H, Peng G, Xue J.
    Hum Exp Toxicol; 2015 Feb 22; 34(2):179-90. PubMed ID: 24837741
    [Abstract] [Full Text] [Related]

  • 17. Helicobacter pylori vacuolating cytotoxin enters cells, localizes to the mitochondria, and induces mitochondrial membrane permeability changes correlated to toxin channel activity.
    Willhite DC, Blanke SR.
    Cell Microbiol; 2004 Feb 22; 6(2):143-54. PubMed ID: 14706100
    [Abstract] [Full Text] [Related]

  • 18. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A, Brady NR.
    J Biol Chem; 2015 Sep 04; 290(36):22005-18. PubMed ID: 26134559
    [Abstract] [Full Text] [Related]

  • 19. Bak and Bax are non-redundant during infection- and DNA damage-induced apoptosis.
    Kepp O, Rajalingam K, Kimmig S, Rudel T.
    EMBO J; 2007 Feb 07; 26(3):825-34. PubMed ID: 17235284
    [Abstract] [Full Text] [Related]

  • 20. Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K.
    Sundararajan R, Cuconati A, Nelson D, White E.
    J Biol Chem; 2001 Nov 30; 276(48):45120-7. PubMed ID: 11571294
    [Abstract] [Full Text] [Related]

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