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Journal Abstract Search

201 related items for PubMed ID: 16446176

  • 1. Parasite cysteine proteinase interactions with alpha 2-macroglobulin or kininogens: differential pathways modulating inflammation and innate immunity in infection by pathogenic trypanosomatids.
    Scharfstein J.
    Immunobiology; 2006; 211(1-2):117-25. PubMed ID: 16446176
    [Abstract] [Full Text] [Related]

  • 2. Kininogens coordinate adaptive immunity through the proteolytic release of bradykinin, an endogenous danger signal driving dendritic cell maturation.
    Scharfstein J, Schmitz V, Svensjö E, Granato A, Monteiro AC.
    Scand J Immunol; 2007; 66(2-3):128-36. PubMed ID: 17635790
    [Abstract] [Full Text] [Related]

  • 3. Angiotensin-converting enzyme limits inflammation elicited by Trypanosoma cruzi cysteine proteases: a peripheral mechanism regulating adaptive immunity via the innate kinin pathway.
    Scharfstein J, Monteiro AC, Schmitz V, Svensjö E.
    Biol Chem; 2008 Aug; 389(8):1015-24. PubMed ID: 18979626
    [Abstract] [Full Text] [Related]

  • 4. Roles of naturally occurring protease inhibitors in the modulation of host cell signaling and cellular invasion by Trypanosoma cruzi.
    Scharfstein J, Lima AP.
    Subcell Biochem; 2008 Aug; 47():140-54. PubMed ID: 18512348
    [Abstract] [Full Text] [Related]

  • 5. Cooperative activation of TLR2 and bradykinin B2 receptor is required for induction of type 1 immunity in a mouse model of subcutaneous infection by Trypanosoma cruzi.
    Monteiro AC, Schmitz V, Svensjo E, Gazzinelli RT, Almeida IC, Todorov A, de Arruda LB, Torrecilhas AC, Pesquero JB, Morrot A, Bouskela E, Bonomo A, Lima AP, Müller-Esterl W, Scharfstein J.
    J Immunol; 2006 Nov 01; 177(9):6325-35. PubMed ID: 17056563
    [Abstract] [Full Text] [Related]

  • 6. Infection-associated vasculopathy in experimental chagas disease pathogenic roles of endothelin and kinin pathways.
    Scharfstein J, Andrade D.
    Adv Parasitol; 2011 Nov 01; 76():101-27. PubMed ID: 21884889
    [Abstract] [Full Text] [Related]

  • 7. Human T cell responses against the major cysteine proteinase (cruzipain) of Trypanosoma cruzi: role of the multifunctional alpha 2-macroglobulin receptor in antigen presentation by monocytes.
    Morrot A, Strickland DK, Higuchi Mde L, Reis M, Pedrosa R, Scharfstein J.
    Int Immunol; 1997 Jun 01; 9(6):825-34. PubMed ID: 9199965
    [Abstract] [Full Text] [Related]

  • 8. Proteolytic generation of kinins in tissues infected by Trypanosoma cruzi depends on CXC chemokine secretion by macrophages activated via Toll-like 2 receptors.
    Schmitz V, Svensjö E, Serra RR, Teixeira MM, Scharfstein J.
    J Leukoc Biol; 2009 Jun 01; 85(6):1005-14. PubMed ID: 19293401
    [Abstract] [Full Text] [Related]

  • 9. Host cell invasion by Trypanosoma cruzi is potentiated by activation of bradykinin B(2) receptors.
    Scharfstein J, Schmitz V, Morandi V, Capella MM, Lima AP, Morrot A, Juliano L, Müller-Esterl W.
    J Exp Med; 2000 Nov 06; 192(9):1289-300. PubMed ID: 11067878
    [Abstract] [Full Text] [Related]

  • 10. Trypanosoma cruzi: cruzipain and membrane-bound cysteine proteinase isoform(s) interacts with human alpha(2)-macroglobulin and pregnancy zone protein.
    Ramos AM, Duschak VG, Gerez de Burgos NM, Barboza M, Remedi MS, Vides MA, Chiabrando GA.
    Exp Parasitol; 2002 Feb 06; 100(2):121-30. PubMed ID: 12054702
    [Abstract] [Full Text] [Related]

  • 11. Chagasin, the endogenous cysteine-protease inhibitor of Trypanosoma cruzi, modulates parasite differentiation and invasion of mammalian cells.
    Santos CC, Sant'anna C, Terres A, Cunha-e-Silva NL, Scharfstein J, de A Lima AP.
    J Cell Sci; 2005 Mar 01; 118(Pt 5):901-15. PubMed ID: 15713748
    [Abstract] [Full Text] [Related]

  • 12. Immune system recognition of Trypanosoma cruzi.
    Tarleton RL.
    Curr Opin Immunol; 2007 Aug 01; 19(4):430-4. PubMed ID: 17651955
    [Abstract] [Full Text] [Related]

  • 13. Subverting bradykinin-evoked inflammation by co-opting the contact system: lessons from survival strategies of Trypanosoma cruzi.
    Scharfstein J.
    Curr Opin Hematol; 2018 Sep 01; 25(5):347-357. PubMed ID: 30028741
    [Abstract] [Full Text] [Related]

  • 14. Innate and acquired immunity in the pathogenesis of Chagas disease.
    Golgher D, Gazzinelli RT.
    Autoimmunity; 2004 Aug 01; 37(5):399-409. PubMed ID: 15621564
    [Abstract] [Full Text] [Related]

  • 15. Heparan sulfate modulates kinin release by Trypanosoma cruzi through the activity of cruzipain.
    Lima AP, Almeida PC, Tersariol IL, Schmitz V, Schmaier AH, Juliano L, Hirata IY, Müller-Esterl W, Chagas JR, Scharfstein J.
    J Biol Chem; 2002 Feb 22; 277(8):5875-81. PubMed ID: 11726662
    [Abstract] [Full Text] [Related]

  • 16. C5a and bradykinin receptor cross-talk regulates innate and adaptive immunity in Trypanosoma cruzi infection.
    Schmitz V, Almeida LN, Svensjö E, Monteiro AC, Köhl J, Scharfstein J.
    J Immunol; 2014 Oct 01; 193(7):3613-23. PubMed ID: 25187655
    [Abstract] [Full Text] [Related]

  • 17. Crystal structure of chagasin, the endogenous cysteine-protease inhibitor from Trypanosoma cruzi.
    Figueiredo da Silva AA, de Carvalho Vieira L, Krieger MA, Goldenberg S, Zanchin NI, Guimarães BG.
    J Struct Biol; 2007 Feb 01; 157(2):416-23. PubMed ID: 17011790
    [Abstract] [Full Text] [Related]

  • 18. Development of alpha-keto-based inhibitors of cruzain, a cysteine protease implicated in Chagas disease.
    Choe Y, Brinen LS, Price MS, Engel JC, Lange M, Grisostomi C, Weston SG, Pallai PV, Cheng H, Hardy LW, Hartsough DS, McMakin M, Tilton RF, Baldino CM, Craik CS.
    Bioorg Med Chem; 2005 Mar 15; 13(6):2141-56. PubMed ID: 15727867
    [Abstract] [Full Text] [Related]

  • 19. The role of Toll-like receptors and adaptive immunity in the development of protective or pathological immune response triggered by the Trypanosoma cruzi protozoan.
    Pellegrini A, Guiñazu N, Giordanengo L, Cano RC, Gea S.
    Future Microbiol; 2011 Dec 15; 6(12):1521-33. PubMed ID: 22122446
    [Abstract] [Full Text] [Related]

  • 20. A new cruzipain-mediated pathway of human cell invasion by Trypanosoma cruzi requires trypomastigote membranes.
    Aparicio IM, Scharfstein J, Lima AP.
    Infect Immun; 2004 Oct 15; 72(10):5892-902. PubMed ID: 15385491
    [Abstract] [Full Text] [Related]

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