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264 related items for PubMed ID: 16448134

  • 1. Substrate specificity of an active dinuclear Zn(II) catalyst for cleavage of RNA analogues and a dinucleoside.
    O'Donoghue A, Pyun SY, Yang MY, Morrow JR, Richard JP.
    J Am Chem Soc; 2006 Feb 08; 128(5):1615-21. PubMed ID: 16448134
    [Abstract] [Full Text] [Related]

  • 2. Structure-activity studies on the cleavage of an RNA analogue by a potent dinuclear metal ion catalyst: effect of changing the metal ion.
    Iranzo O, Richard JP, Morrow JR.
    Inorg Chem; 2004 Mar 08; 43(5):1743-50. PubMed ID: 14989667
    [Abstract] [Full Text] [Related]

  • 3. Dinuclear Zn(II) complex catalyzed phosphodiester cleavage proceeds via a concerted mechanism: a density functional theory study.
    Gao H, Ke Z, DeYonker NJ, Wang J, Xu H, Mao ZW, Phillips DL, Zhao C.
    J Am Chem Soc; 2011 Mar 09; 133(9):2904-15. PubMed ID: 21319769
    [Abstract] [Full Text] [Related]

  • 4. Physical and kinetic analysis of the cooperative role of metal ions in catalysis of phosphodiester cleavage by a dinuclear Zn(II) complex.
    Iranzo O, Kovalevsky AY, Morrow JR, Richard JP.
    J Am Chem Soc; 2003 Feb 19; 125(7):1988-93. PubMed ID: 12580627
    [Abstract] [Full Text] [Related]

  • 5. Cleavage of a RNA analog containing uridine by a bifunctional dinuclear Zn(II) catalyst.
    Rossiter CS, Mathews RA, del Mundo IM, Morrow JR.
    J Inorg Biochem; 2009 Jan 19; 103(1):64-71. PubMed ID: 18952297
    [Abstract] [Full Text] [Related]

  • 6. Cooperativity between metal ions in the cleavage of phosphate diesters and RNA by dinuclear Zn(II) catalysts.
    Iranzo O, Elmer T, Richard JP, Morrow JR.
    Inorg Chem; 2003 Dec 01; 42(24):7737-46. PubMed ID: 14632489
    [Abstract] [Full Text] [Related]

  • 7. The dinuclear Zn(II) complex catalyzed cyclization of a series of 2-hydroxypropyl aryl phosphate RNA models: progressive change in mechanism from rate-limiting P-O bond cleavage to substrate binding.
    Bunn SE, Liu CT, Lu ZL, Neverov AA, Brown RS.
    J Am Chem Soc; 2007 Dec 26; 129(51):16238-48. PubMed ID: 18047345
    [Abstract] [Full Text] [Related]

  • 8. A minimalist approach to understanding the efficiency of mononuclear Zn(II) complexes as catalysts of cleavage of an RNA analog.
    Mathews RA, Rossiter CS, Morrow JR, Richard JP.
    Dalton Trans; 2007 Sep 14; (34):3804-11. PubMed ID: 17712447
    [Abstract] [Full Text] [Related]

  • 9. Biomimetic cleavage of RNA models promoted by a dinuclear Zn(II) complex in ethanol. Greater than 30 kcal/mol stabilization of the transition state for cleavage of a phosphate diester.
    Liu CT, Neverov AA, Brown RS.
    J Am Chem Soc; 2008 Dec 10; 130(49):16711-20. PubMed ID: 19554695
    [Abstract] [Full Text] [Related]

  • 10. A transition state analog for phosphate diester cleavage catalyzed by a small enzyme-like metal ion complex.
    Yang MY, Morrow JR, Richard JP.
    Bioorg Chem; 2007 Oct 10; 35(5):366-74. PubMed ID: 17434205
    [Abstract] [Full Text] [Related]

  • 11. A simple DNase model system comprising a dinuclear Zn(II) complex in methanol accelerates the cleavage of a series of methyl aryl phosphate diesters by 10(11)-10(13).
    Neverov AA, Liu CT, Bunn SE, Edwards D, White CJ, Melnychuk SA, Brown RS.
    J Am Chem Soc; 2008 May 21; 130(20):6639-49. PubMed ID: 18479083
    [Abstract] [Full Text] [Related]

  • 12. An azacrown-functionalized peptide as a metal ion based catalyst for the cleavage of a RNA-model substrate.
    Rossi P, Felluga F, Tecilla P, Formaggio F, Crisma M, Toniolo C, Scrimin P.
    Biopolymers; 2000 May 21; 55(6):496-501. PubMed ID: 11304677
    [Abstract] [Full Text] [Related]

  • 13. Rapid three-step cleavage of RNA and DNA model systems promoted by a dinuclear Cu(II) complex in methanol. energetic origins of the catalytic efficacy.
    Lu ZL, Liu CT, Neverov AA, Brown RS.
    J Am Chem Soc; 2007 Sep 19; 129(37):11642-52. PubMed ID: 17715924
    [Abstract] [Full Text] [Related]

  • 14. Investigation of the effect of oxy bridging groups in dinuclear Zn(II) complexes that catalyze the cleavage of a simple phosphate diester RNA analogue.
    Mohamed MF, Neverov AA, Brown RS.
    Inorg Chem; 2009 Dec 07; 48(23):11425-33. PubMed ID: 19874005
    [Abstract] [Full Text] [Related]

  • 15. Solvent deuterium isotope effects on phosphodiester cleavage catalyzed by an extraordinarily active Zn(II) complex.
    Yang MY, Iranzo O, Richard JP, Morrow JR.
    J Am Chem Soc; 2005 Feb 02; 127(4):1064-5. PubMed ID: 15669821
    [Abstract] [Full Text] [Related]

  • 16. Cleavage of an RNA model catalyzed by dinuclear Zn(II) complexes containing rate-accelerating pendants. Comparison of the catalytic benefits of H-bonding and hydrophobic substituents.
    Mohamed MF, Brown RS.
    J Org Chem; 2010 Dec 17; 75(24):8471-7. PubMed ID: 21087029
    [Abstract] [Full Text] [Related]

  • 17. Uridine binding by Zn(II) macrocyclic complexes: diversion of RNA cleavage catalysts.
    Rossiter CS, Mathews RA, Morrow JR.
    Inorg Chem; 2005 Dec 12; 44(25):9397-404. PubMed ID: 16323926
    [Abstract] [Full Text] [Related]

  • 18. Cleavage and isomerization of UpU promoted by dinuclear metal ion complexes.
    Linjalahti H, Feng G, Mareque-Rivas JC, Mikkola S, Williams NH.
    J Am Chem Soc; 2008 Apr 02; 130(13):4232-3. PubMed ID: 18324817
    [Abstract] [Full Text] [Related]

  • 19. An asymmetric dizinc phosphodiesterase model with phenolate and carboxylate bridges.
    Chen J, Wang X, Zhu Y, Lin J, Yang X, Li Y, Lu Y, Guo Z.
    Inorg Chem; 2005 May 16; 44(10):3422-30. PubMed ID: 15877422
    [Abstract] [Full Text] [Related]

  • 20. Complex formation of divalent metal ions with uridine 5'-O-thiomonophosphate or methyl thiophosphate: comparison of complex stabilities with those of the parent phosphate ligands.
    Da Costa CP, Okruszek A, Sigel H.
    Chembiochem; 2003 Jul 07; 4(7):593-602. PubMed ID: 12851928
    [Abstract] [Full Text] [Related]

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