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294 related items for PubMed ID: 16452469

  • 1. Extracellular signal-regulated kinase-dependent proliferation is mediated through the protein kinase A/B-Raf pathway in human uveal melanoma cells.
    Calipel A, Mouriaux F, Glotin AL, Malecaze F, Faussat AM, Mascarelli F.
    J Biol Chem; 2006 Apr 07; 281(14):9238-50. PubMed ID: 16452469
    [Abstract] [Full Text] [Related]

  • 2. 17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines.
    Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F.
    Invest Ophthalmol Vis Sci; 2008 Jun 07; 49(6):2348-56. PubMed ID: 18281615
    [Abstract] [Full Text] [Related]

  • 3. The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK.
    Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F.
    Invest Ophthalmol Vis Sci; 2010 Jan 07; 51(1):421-9. PubMed ID: 19661225
    [Abstract] [Full Text] [Related]

  • 4. cAMP inhibits the proliferation of retinal pigmented epithelial cells through the inhibition of ERK1/2 in a PKA-independent manner.
    Hecquet C, Lefevre G, Valtink M, Engelmann K, Mascarelli F.
    Oncogene; 2002 Sep 05; 21(39):6101-12. PubMed ID: 12203122
    [Abstract] [Full Text] [Related]

  • 5. Elastin peptides activate extracellular signal-regulated kinase 1/2 via a Ras-independent mechanism requiring both p110gamma/Raf-1 and protein kinase A/B-Raf signaling in human skin fibroblasts.
    Duca L, Lambert E, Debret R, Rothhut B, Blanchevoye C, Delacoux F, Hornebeck W, Martiny L, Debelle L.
    Mol Pharmacol; 2005 Apr 05; 67(4):1315-24. PubMed ID: 15653554
    [Abstract] [Full Text] [Related]

  • 6. Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation.
    Li Y, Takahashi M, Stork PJS.
    J Biol Chem; 2013 Sep 20; 288(38):27646-27657. PubMed ID: 23893412
    [Abstract] [Full Text] [Related]

  • 7. Activation of the FGF2/FGFR1 autocrine loop for cell proliferation and survival in uveal melanoma cells.
    Lefèvre G, Babchia N, Calipel A, Mouriaux F, Faussat AM, Mrzyk S, Mascarelli F.
    Invest Ophthalmol Vis Sci; 2009 Mar 20; 50(3):1047-57. PubMed ID: 19029025
    [Abstract] [Full Text] [Related]

  • 8. Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway.
    Calipel A, Lefevre G, Pouponnot C, Mouriaux F, Eychène A, Mascarelli F.
    J Biol Chem; 2003 Oct 24; 278(43):42409-18. PubMed ID: 12917419
    [Abstract] [Full Text] [Related]

  • 9. Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase) pathway.
    Kim EJ, Juhnn YS.
    J Biol Chem; 2015 Apr 10; 290(15):9604-13. PubMed ID: 25713071
    [Abstract] [Full Text] [Related]

  • 10. Protein kinase A and B-Raf mediate extracellular signal-regulated kinase activation by thyrotropin.
    Vuchak LA, Tsygankova OM, Prendergast GV, Meinkoth JL.
    Mol Pharmacol; 2009 Nov 10; 76(5):1123-9. PubMed ID: 19720729
    [Abstract] [Full Text] [Related]

  • 11. Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.
    Marzec M, Kasprzycka M, Liu X, Raghunath PN, Wlodarski P, Wasik MA.
    Oncogene; 2007 Feb 08; 26(6):813-21. PubMed ID: 16909118
    [Abstract] [Full Text] [Related]

  • 12. Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.
    Ehses JA, Pelech SL, Pederson RA, McIntosh CH.
    J Biol Chem; 2002 Oct 04; 277(40):37088-97. PubMed ID: 12138104
    [Abstract] [Full Text] [Related]

  • 13. ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells.
    Cesi G, Walbrecq G, Zimmer A, Kreis S, Haan C.
    Mol Cancer; 2017 Jun 08; 16(1):102. PubMed ID: 28595656
    [Abstract] [Full Text] [Related]

  • 14. Protein Kinase A-independent Ras Protein Activation Cooperates with Rap1 Protein to Mediate Activation of the Extracellular Signal-regulated Kinases (ERK) by cAMP.
    Li Y, Dillon TJ, Takahashi M, Earley KT, Stork PJ.
    J Biol Chem; 2016 Oct 07; 291(41):21584-21595. PubMed ID: 27531745
    [Abstract] [Full Text] [Related]

  • 15. Antitumor efficacy of the novel RAF inhibitor GDC-0879 is predicted by BRAFV600E mutational status and sustained extracellular signal-regulated kinase/mitogen-activated protein kinase pathway suppression.
    Hoeflich KP, Herter S, Tien J, Wong L, Berry L, Chan J, O'Brien C, Modrusan Z, Seshagiri S, Lackner M, Stern H, Choo E, Murray L, Friedman LS, Belvin M.
    Cancer Res; 2009 Apr 01; 69(7):3042-51. PubMed ID: 19276360
    [Abstract] [Full Text] [Related]

  • 16. Flagellin and lipopolysaccharide stimulate the MEK-ERK signaling pathway in chicken heterophils through differential activation of the small GTPases, Ras and Rap1.
    Kogut MH, Genovese KJ, He H.
    Mol Immunol; 2007 Mar 01; 44(7):1729-36. PubMed ID: 17045653
    [Abstract] [Full Text] [Related]

  • 17. Cyclic AMP signaling as a mediator of vasculogenic mimicry in aggressive human melanoma cells in vitro.
    Lissitzky JC, Parriaux D, Ristorcelli E, Vérine A, Lombardo D, Verrando P.
    Cancer Res; 2009 Feb 01; 69(3):802-9. PubMed ID: 19176384
    [Abstract] [Full Text] [Related]

  • 18. Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib.
    Spirli C, Morell CM, Locatelli L, Okolicsanyi S, Ferrero C, Kim AK, Fabris L, Fiorotto R, Strazzabosco M.
    Hepatology; 2012 Dec 01; 56(6):2363-74. PubMed ID: 22653837
    [Abstract] [Full Text] [Related]

  • 19. Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS.
    Zuidervaart W, van Nieuwpoort F, Stark M, Dijkman R, Packer L, Borgstein AM, Pavey S, van der Velden P, Out C, Jager MJ, Hayward NK, Gruis NA.
    Br J Cancer; 2005 Jun 06; 92(11):2032-8. PubMed ID: 15928660
    [Abstract] [Full Text] [Related]

  • 20. Identification of aurora kinase B and Wee1-like protein kinase as downstream targets of (V600E)B-RAF in melanoma.
    Sharma A, Madhunapantula SV, Gowda R, Berg A, Neves RI, Robertson GP.
    Am J Pathol; 2013 Apr 06; 182(4):1151-62. PubMed ID: 23416158
    [Abstract] [Full Text] [Related]

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