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Journal Abstract Search

294 related items for PubMed ID: 16452469

  • 21. Identification of unique MEK-dependent genes in GNAQ mutant uveal melanoma involved in cell growth, tumor cell invasion, and MEK resistance.
    Ambrosini G, Pratilas CA, Qin LX, Tadi M, Surriga O, Carvajal RD, Schwartz GK.
    Clin Cancer Res; 2012 Jul 01; 18(13):3552-61. PubMed ID: 22550165
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  • 22. Renal activation of extracellular signal-regulated kinase in rats with autosomal-dominant polycystic kidney disease.
    Nagao S, Yamaguchi T, Kusaka M, Maser RL, Takahashi H, Cowley BD, Grantham JJ.
    Kidney Int; 2003 Feb 01; 63(2):427-37. PubMed ID: 12631108
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  • 23. Pyrophosphorolysis detects B-RAF mutations in primary uveal melanoma.
    Maat W, Kilic E, Luyten GP, de Klein A, Jager MJ, Gruis NA, Van der Velden PA.
    Invest Ophthalmol Vis Sci; 2008 Jan 01; 49(1):23-7. PubMed ID: 18172070
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  • 24. Phosphorylation of Rap1 by cAMP-dependent Protein Kinase (PKA) Creates a Binding Site for KSR to Sustain ERK Activation by cAMP.
    Takahashi M, Li Y, Dillon TJ, Stork PJ.
    J Biol Chem; 2017 Jan 27; 292(4):1449-1461. PubMed ID: 28003362
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  • 25. Active notch protects MAPK activated melanoma cell lines from MEK inhibitor cobimetinib.
    Porcelli L, Mazzotta A, Garofoli M, Di Fonte R, Guida G, Guida M, Tommasi S, Azzariti A.
    Biomed Pharmacother; 2021 Jan 27; 133():111006. PubMed ID: 33202284
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  • 26. Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells.
    Conner SR, Scott G, Aplin AE.
    J Biol Chem; 2003 Sep 05; 278(36):34548-54. PubMed ID: 12821662
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  • 27. Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling.
    Huntington JT, Shields JM, Der CJ, Wyatt CA, Benbow U, Slingluff CL, Brinckerhoff CE.
    J Biol Chem; 2004 Aug 06; 279(32):33168-76. PubMed ID: 15184373
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  • 28. C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).
    Karreth FA, DeNicola GM, Winter SP, Tuveson DA.
    Mol Cell; 2009 Nov 13; 36(3):477-86. PubMed ID: 19917255
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  • 29. Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress.
    Martinez R, Huang W, Samadani R, Mackowiak B, Centola G, Chen L, Conlon IL, Hom K, Kane MA, Fletcher S, Shapiro P.
    J Pharmacol Exp Ther; 2021 Jan 13; 376(1):84-97. PubMed ID: 33109619
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  • 30. Tumor-derived fibronectin is involved in melanoma cell invasion and regulated by V600E B-Raf signaling pathway.
    Gaggioli C, Robert G, Bertolotto C, Bailet O, Abbe P, Spadafora A, Bahadoran P, Ortonne JP, Baron V, Ballotti R, Tartare-Deckert S.
    J Invest Dermatol; 2007 Feb 13; 127(2):400-10. PubMed ID: 16960555
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  • 31. Roles of stem cell factor/c-Kit and effects of Glivec/STI571 in human uveal melanoma cell tumorigenesis.
    Lefevre G, Glotin AL, Calipel A, Mouriaux F, Tran T, Kherrouche Z, Maurage CA, Auclair C, Mascarelli F.
    J Biol Chem; 2004 Jul 23; 279(30):31769-79. PubMed ID: 15145934
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  • 32. Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth.
    Hao H, Muniz-Medina VM, Mehta H, Thomas NE, Khazak V, Der CJ, Shields JM.
    Mol Cancer Ther; 2007 Aug 23; 6(8):2220-9. PubMed ID: 17699719
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  • 33. Protein kinase C alpha trigger Ras and Raf-independent MEK/ERK activation for TPA-induced growth inhibition of human hepatoma cell HepG2.
    Wen-Sheng W.
    Cancer Lett; 2006 Jul 28; 239(1):27-35. PubMed ID: 16169661
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  • 34. Akt3 and mutant V600E B-Raf cooperate to promote early melanoma development.
    Cheung M, Sharma A, Madhunapantula SV, Robertson GP.
    Cancer Res; 2008 May 01; 68(9):3429-39. PubMed ID: 18451171
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  • 35. Protein kinase C inhibitor AEB071 targets ocular melanoma harboring GNAQ mutations via effects on the PKC/Erk1/2 and PKC/NF-κB pathways.
    Wu X, Li J, Zhu M, Fletcher JA, Hodi FS.
    Mol Cancer Ther; 2012 Sep 01; 11(9):1905-14. PubMed ID: 22653968
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  • 36. Involvement of PI3K/Akt signaling pathway in hepatocyte growth factor-induced migration of uveal melanoma cells.
    Ye M, Hu D, Tu L, Zhou X, Lu F, Wen B, Wu W, Lin Y, Zhou Z, Qu J.
    Invest Ophthalmol Vis Sci; 2008 Feb 01; 49(2):497-504. PubMed ID: 18234991
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  • 37. Targeting mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases.
    Sharma A, Tran MA, Liang S, Sharma AK, Amin S, Smith CD, Dong C, Robertson GP.
    Cancer Res; 2006 Aug 15; 66(16):8200-9. PubMed ID: 16912199
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  • 38. Cyclic AMP differentially regulates cell proliferation of normal human keratinocytes through ERK activation depending on the expression pattern of B-Raf.
    Takahashi H, Honma M, Miyauchi Y, Nakamura S, Ishida-Yamamoto A, Iizuka H.
    Arch Dermatol Res; 2004 Jul 15; 296(2):74-82. PubMed ID: 15278365
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  • 39. The protein kinase C inhibitor enzastaurin exhibits antitumor activity against uveal melanoma.
    Wu X, Zhu M, Fletcher JA, Giobbie-Hurder A, Hodi FS.
    PLoS One; 2012 Jul 15; 7(1):e29622. PubMed ID: 22253748
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  • 40. KRas-ERK signalling promotes the onset and maintenance of uveal melanoma through regulating JMJD6-mediated H2A.X phosphorylation at tyrosine 39.
    Li Y, Yu P, Zou Y, Cai W, Sun W, Han N.
    Artif Cells Nanomed Biotechnol; 2019 Dec 15; 47(1):4257-4265. PubMed ID: 31736361
    [Abstract] [Full Text] [Related]

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