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569 related items for PubMed ID: 16459298

  • 1. Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway.
    Svärd J, Heby-Henricson K, Persson-Lek M, Rozell B, Lauth M, Bergström A, Ericson J, Toftgård R, Teglund S.
    Dev Cell; 2006 Feb; 10(2):187-97. PubMed ID: 16459298
    [Abstract] [Full Text] [Related]

  • 2. Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved.
    Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, Gacayan R, Zhang X, Hui CC, Chuang PT.
    Genes Dev; 2009 Aug 15; 23(16):1910-28. PubMed ID: 19684112
    [Abstract] [Full Text] [Related]

  • 3. Hedgehog signaling is synergistically enhanced by nutritional deprivation and ligand stimulation in human fibroblasts of Gorlin syndrome.
    Mizuochi H, Fujii K, Shiohama T, Uchikawa H, Shimojo N.
    Biochem Biophys Res Commun; 2015 Feb 13; 457(3):318-23. PubMed ID: 25576868
    [Abstract] [Full Text] [Related]

  • 4. Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.
    Lin C, Yao E, Wang K, Nozawa Y, Shimizu H, Johnson JR, Chen JN, Krogan NJ, Chuang PT.
    Genes Dev; 2014 Nov 15; 28(22):2547-63. PubMed ID: 25403183
    [Abstract] [Full Text] [Related]

  • 5. Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures.
    Cohen JR, Resnick DZ, Niewiadomski P, Dong H, Liau LM, Waschek JA.
    BMC Cancer; 2010 Dec 09; 10():676. PubMed ID: 21143927
    [Abstract] [Full Text] [Related]

  • 6. Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling.
    Zhang Z, Shen L, Law K, Zhang Z, Liu X, Hua H, Li S, Huang H, Yue S, Hui CC, Cheng SY.
    Mol Cell Biol; 2017 Feb 01; 37(3):. PubMed ID: 27849569
    [Abstract] [Full Text] [Related]

  • 7. Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused.
    Cooper AF, Yu KP, Brueckner M, Brailey LL, Johnson L, McGrath JM, Bale AE.
    Development; 2005 Oct 01; 132(19):4407-17. PubMed ID: 16155214
    [Abstract] [Full Text] [Related]

  • 8. A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes.
    Tukachinsky H, Lopez LV, Salic A.
    J Cell Biol; 2010 Oct 18; 191(2):415-28. PubMed ID: 20956384
    [Abstract] [Full Text] [Related]

  • 9. A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response.
    Oh S, Kato M, Zhang C, Guo Y, Beachy PA.
    PLoS One; 2015 Oct 18; 10(8):e0135804. PubMed ID: 26271100
    [Abstract] [Full Text] [Related]

  • 10. HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth.
    Pandolfi S, Montagnani V, Lapucci A, Stecca B.
    Cell Death Differ; 2015 Dec 18; 22(12):2006-19. PubMed ID: 26024388
    [Abstract] [Full Text] [Related]

  • 11. Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists.
    Frank-Kamenetsky M, Zhang XM, Bottega S, Guicherit O, Wichterle H, Dudek H, Bumcrot D, Wang FY, Jones S, Shulok J, Rubin LL, Porter JA.
    J Biol; 2002 Nov 06; 1(2):10. PubMed ID: 12437772
    [Abstract] [Full Text] [Related]

  • 12. Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.
    Lipinski RJ, Gipp JJ, Zhang J, Doles JD, Bushman W.
    Exp Cell Res; 2006 Jul 01; 312(11):1925-38. PubMed ID: 16571352
    [Abstract] [Full Text] [Related]

  • 13. Mouse Rab23 regulates hedgehog signaling from smoothened to Gli proteins.
    Eggenschwiler JT, Bulgakov OV, Qin J, Li T, Anderson KV.
    Dev Biol; 2006 Feb 01; 290(1):1-12. PubMed ID: 16364285
    [Abstract] [Full Text] [Related]

  • 14. Sonic hedgehog signaling by the patched-smoothened receptor complex.
    Murone M, Rosenthal A, de Sauvage FJ.
    Curr Biol; 1999 Jan 28; 9(2):76-84. PubMed ID: 10021362
    [Abstract] [Full Text] [Related]

  • 15. Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site.
    Agren M, Kogerman P, Kleman MI, Wessling M, Toftgård R.
    Gene; 2004 Apr 14; 330():101-14. PubMed ID: 15087129
    [Abstract] [Full Text] [Related]

  • 16. Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.
    Lin C, Chen MH, Yao E, Song H, Gacayan R, Hui CC, Chuang PT.
    Dev Biol; 2014 Aug 15; 392(2):324-33. PubMed ID: 24886827
    [Abstract] [Full Text] [Related]

  • 17. Expression of hedgehog signalling components in adult mouse testis.
    Szczepny A, Hime GR, Loveland KL.
    Dev Dyn; 2006 Nov 15; 235(11):3063-70. PubMed ID: 16958114
    [Abstract] [Full Text] [Related]

  • 18. Cilia and Hedgehog responsiveness in the mouse.
    Huangfu D, Anderson KV.
    Proc Natl Acad Sci U S A; 2005 Aug 09; 102(32):11325-30. PubMed ID: 16061793
    [Abstract] [Full Text] [Related]

  • 19. Hedgehog signaling promotes the degradation of tumor suppressor Sufu through the ubiquitin-proteasome pathway.
    Yue S, Chen Y, Cheng SY.
    Oncogene; 2009 Jan 29; 28(4):492-9. PubMed ID: 18997815
    [Abstract] [Full Text] [Related]

  • 20. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers.
    Long J, Li B, Rodriguez-Blanco J, Pastori C, Volmar CH, Wahlestedt C, Capobianco A, Bai F, Pei XH, Ayad NG, Robbins DJ.
    J Biol Chem; 2014 Dec 19; 289(51):35494-502. PubMed ID: 25355313
    [Abstract] [Full Text] [Related]

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