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255 related items for PubMed ID: 1646219

  • 1. Specificity of low dose fadrozole hydrochloride (CGS 16949A) as an aromatase inhibitor.
    Santen RJ, Demers LM, Lynch J, Harvey H, Lipton A, Mulagha M, Hanagan J, Garber JE, Henderson IC, Navari RM.
    J Clin Endocrinol Metab; 1991 Jul; 73(1):99-106. PubMed ID: 1646219
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of aromatase with CGS 16949A in postmenopausal women.
    Santen RJ, Demers LM, Adlercreutz H, Harvey H, Santner S, Sanders S, Lipton A.
    J Clin Endocrinol Metab; 1989 Jan; 68(1):99-106. PubMed ID: 2521224
    [Abstract] [Full Text] [Related]

  • 3. The effects of CGS 16949A, an aromatase inhibitor on adrenal mineralocorticoid biosynthesis.
    Demers LM, Melby JC, Wilson TE, Lipton A, Harvey HA, Santen RJ.
    J Clin Endocrinol Metab; 1990 Apr; 70(4):1162-6. PubMed ID: 2156889
    [Abstract] [Full Text] [Related]

  • 4. The new aromatase inhibitor CGS-16949A suppresses aldosterone and cortisol production by human adrenal cells in vitro.
    Lamberts SW, Bruining HA, Marzouk H, Zuiderwijk J, Uitterlinden P, Blijd JJ, Hackeng WH, De Jong FH.
    J Clin Endocrinol Metab; 1989 Oct; 69(4):896-901. PubMed ID: 2550511
    [Abstract] [Full Text] [Related]

  • 5. Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in healthy postmenopausal women.
    Iveson TJ, Smith IE, Ahern J, Smithers DA, Trunet PF, Dowsett M.
    J Clin Endocrinol Metab; 1993 Aug; 77(2):324-31. PubMed ID: 8345035
    [Abstract] [Full Text] [Related]

  • 6. Potency and selectivity of the non-steroidal aromatase inhibitor CGS 16949A in postmenopausal breast cancer patients.
    Dowsett M, Stein RC, Mehta A, Coombes RC.
    Clin Endocrinol (Oxf); 1990 May; 32(5):623-34. PubMed ID: 2142026
    [Abstract] [Full Text] [Related]

  • 7. Preliminary study of the treatment of advanced breast cancer in postmenopausal women with the aromatase inhibitor CGS 16949A.
    Stein RC, Dowsett M, Davenport J, Hedley A, Ford HT, Gazet JC, Coombes RC.
    Cancer Res; 1990 Mar 01; 50(5):1381-4. PubMed ID: 2137367
    [Abstract] [Full Text] [Related]

  • 8. Effects of Fadrozole (CGS 16949A) and Letrozole (CGS 20267) on the inhibition of aromatase activity in breast cancer patients.
    Demers LM.
    Breast Cancer Res Treat; 1994 Mar 01; 30(1):95-102. PubMed ID: 7949208
    [Abstract] [Full Text] [Related]

  • 9. In vitro and in vivo studies demonstrating potent and selective estrogen inhibition with the nonsteroidal aromatase inhibitor CGS 16949A.
    Steele RE, Mellor LB, Sawyer WK, Wasvary JM, Browne LJ.
    Steroids; 1987 Mar 01; 50(1-3):147-61. PubMed ID: 2973160
    [Abstract] [Full Text] [Related]

  • 10. A phase I trial of CGS 16949A. A new aromatase inhibitor.
    Lipton A, Harvey HA, Demers LM, Hanagan JR, Mulagha MT, Kochak GM, Fitzsimmons S, Sanders SI, Santen RJ.
    Cancer; 1990 Mar 15; 65(6):1279-85. PubMed ID: 2137721
    [Abstract] [Full Text] [Related]

  • 11. The effects of fadrozole hydrochloride on aldosterone secretion in healthy male subjects.
    Trunet PF, Mueller P, Girard F, Aupetit B, Bhatnagar AS, Zognbi F, Ezzet F, Menard J.
    J Clin Endocrinol Metab; 1992 Mar 15; 74(3):571-6. PubMed ID: 1531483
    [Abstract] [Full Text] [Related]

  • 12. The efficacy of CGS 20267 in suppressing estrogen biosynthesis in patients with advanced stage breast cancer.
    Demers LM, Lipton A, Harvey HA, Kambic KB, Grossberg H, Brady C, Santen RJ.
    J Steroid Biochem Mol Biol; 1993 Mar 15; 44(4-6):687-91. PubMed ID: 8476785
    [Abstract] [Full Text] [Related]

  • 13. Effect of aromatase inhibitors on estrogen 2-hydroxylase in rat liver.
    Purba HS, King EJ, Richert P, Bhatnagar AS.
    J Steroid Biochem Mol Biol; 1994 Feb 15; 48(2-3):215-9. PubMed ID: 8142297
    [Abstract] [Full Text] [Related]

  • 14. The influence of CGS 16949A on peripheral aromatisation in breast cancer patients.
    Lønning PE, Jacobs S, Jones A, Haynes B, Powles T, Dowsett M.
    Br J Cancer; 1991 May 15; 63(5):789-93. PubMed ID: 1828173
    [Abstract] [Full Text] [Related]

  • 15. Evidence that corticosterone is not an obligatory intermediate in aldosterone biosynthesis in the rat adrenal.
    Häusler A, Monnet G, Borer C, Bhatnagar AS.
    J Steroid Biochem; 1989 May 15; 34(1-6):567-70. PubMed ID: 2533953
    [Abstract] [Full Text] [Related]

  • 16. The effect of the aromatase inhibitor, rogletimide (pyridoglutethimide), on guinea pig adrenal cell steroidogenesis and placental microsomal aromatase activity: comparison with aminoglutethimide and CGS 16949A.
    Newton CJ, Mehta A, Dowsett M.
    J Steroid Biochem Mol Biol; 1991 Nov 15; 39(5A):723-7. PubMed ID: 1659868
    [Abstract] [Full Text] [Related]

  • 17. Highly selective inhibition of estrogen biosynthesis by CGS 20267, a new non-steroidal aromatase inhibitor.
    Bhatnagar AS, Häusler A, Schieweck K, Lang M, Bowman R.
    J Steroid Biochem Mol Biol; 1990 Dec 20; 37(6):1021-7. PubMed ID: 2149502
    [Abstract] [Full Text] [Related]

  • 18. Antiproliferative effect of the new aromatase inhibitor fadrozole on pre- and postmenopausal models of rat mammary tumor.
    Tanaka M, Yano S, Hasegawa Y, Nakao K.
    Arzneimittelforschung; 1994 Jun 20; 44(6):774-8. PubMed ID: 8053980
    [Abstract] [Full Text] [Related]

  • 19. Recent progress in development of aromatase inhibitors.
    Santen RJ.
    J Steroid Biochem Mol Biol; 1990 Dec 20; 37(6):1029-35. PubMed ID: 2149503
    [Abstract] [Full Text] [Related]

  • 20. Antitumor effects of a nonsteroidal aromatase inhibitor (CGS 16949A) on 7, 12-dimethylbenz[alpha]anthracene-induced mammary tumors in rats.
    Iino Y, Sugamata N, Owada S, Tago T, Sato H, Yokoe T, Maemura M, Morishita Y, Horiuchi R.
    Jpn J Clin Oncol; 1991 Jun 20; 21(3):153-9. PubMed ID: 1834875
    [Abstract] [Full Text] [Related]

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